186803

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 215208..215713 Replicon chromosome
Accession NZ_CP068162
Organism Corynebacterium glucuronolyticum strain FDAARGOS_1111

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag I6I68_RS00945 Protein ID WP_070741463.1
Coordinates 215208..215462 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag I6I68_RS00950 Protein ID WP_070741466.1
Coordinates 215459..215713 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6I68_RS00925 211082..212257 + 1176 WP_005394564.1 LCP family protein -
I6I68_RS00930 212237..212989 - 753 WP_201840457.1 type 1 glutamine amidotransferase domain-containing protein -
I6I68_RS00935 213621..214730 - 1110 WP_201840459.1 acyltransferase family protein -
I6I68_RS00940 215017..215211 + 195 WP_141759689.1 hypothetical protein -
I6I68_RS00945 215208..215462 - 255 WP_070741463.1 Txe/YoeB family addiction module toxin Toxin
I6I68_RS00950 215459..215713 - 255 WP_070741466.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
I6I68_RS00955 216508..216855 - 348 WP_005388132.1 metallopeptidase family protein -
I6I68_RS00960 216852..217838 - 987 WP_084036192.1 septum formation family protein -
I6I68_RS00965 217850..218584 - 735 WP_005388134.1 GntR family transcriptional regulator -
I6I68_RS00970 218626..219882 + 1257 WP_201840461.1 serine--tRNA ligase -
I6I68_RS00975 219879..220652 + 774 WP_005388136.1 HAD family hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10303.68 Da        Isoelectric Point: 9.1653

>T186803 WP_070741463.1 NZ_CP068162:c215462-215208 [Corynebacterium glucuronolyticum]
MKYIWSTQAWNDYLYWQETDRKTVKRINALIKDISRNGNDGIGKPEPLKYELSGYWSRRITDEHRLVYKYTDEALYLAMC
RYHY

Download         Length: 255 bp

>T186803 NZ_CP089772:c3135834-3134950 [Mycobacterium tuberculosis]
GTGGCCGGTCTGACCCGTGCGCTCGTTGCGCGTCACGCTCTTGGTCGGGCCGAGGCATACGACGCCGCTCTGCTCGACGT
CGCCCAGGACCACCTGCTGTACCTGCTGTCGCAGACCGTCCAGTTCGGCGATAACCGCCTGGTGTTCAAAGGCGGTACCA
GCTTACGGAAGTGCCGGCTGGGCAACGTCGGGCGGTTCTCCACTGATCTGGACTTCAGCGCGCCCGACGATGAGGTCGTG
CTGGAGGTGTGCGAGCTGATCGACGGCGCCCGTGTCGGCGGCTTCGAATTCGGCGTGCAGAGCACACGAGGCGACGGCCG
GCATTGGCAGTTGCGGGTGCGGCACACGGAATTGGGCGAGCCCCGGATCGTCGCCAGCGTCGAGTTCGCACGGCGGCCGT
TGGCTTTGCCGTCTGAGCTGCTCGCATTCATCCAGTTGCCGATCCATAAGGCTTACGGTTTTGGGCTGCCGACACTGCCG
GTCGTGGCAGAAGCGGAAGCCTGCGCAGAGAAACTCGCGCGGTACCGCCGCGTTGCGCTGGCACGGGACCTGTACGACCT
GAACCACTTCGCCTCGCGAACGATTGACGAACCGCTCGTGCGGCGGCTGTGGGTGCTCAAGGTGTGGGGTGATGTCGTCG
ATGACCGGCGCGGCACCCGGCCACTACGCGTCGAAGACGTCCTCGCCGCCCGCAGCGAGCACGACTTCCAGCCCGACTCG
ATCGGCGTGCTGACCCGTCCTGTCGCTATGGCTGCCTGGGAAGCTCGCGTTCGGAAGCGATTTGCGTTCCTCACTGACCT
CGACGCCGACGAGCAGCGGTGGGCCGCCTGCGACGAACGGCACCGCCGCGAAGTGGAGAACGCGCTGGCGGTGCTGCGGT
CCTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9496.58 Da        Isoelectric Point: 4.3566

>AT186803 WP_070741466.1 NZ_CP068162:c215713-215459 [Corynebacterium glucuronolyticum]
MKTMSYSESRARYAEVLQSVVDDREEIVITRSGHESAVILSLDDYNSLRETAYLMRSPRNAQLLFEAVTELESGNGTARD
LLPE

Download         Length: 255 bp

>AT186803 NZ_CP089772:c3136724-3135837 [Mycobacterium tuberculosis]
GTGGTGAGCCCAGCCGGCGCCGATCGGCGCATCCCCACGTGGGCGTCACGGGTGGTGTCCGGCCTCGCTCGCGATCGGCC
CGTAGTCGTCACGAAAGAGGATCTGACGCAACGGCTTACAGAGGCTGGGTGTGGACGCGACCCCGACTCCGCCATCCGCG
AACTGCGCCGCATTGGGTGGCTGGTCCAACTGCCGGTGAAAGGCACCTGGGCATTCATTCCCCCCGGCGAGGCCGCCATC
TCGGACCCGTATCTACCGCTGCGCTCGTGGCTGGCCCGTGACCAGAACGCGGGCTTCATGCTGGCCGGTGCATCCGCAGC
GTGGCACCTCGGATACCTGGACCGCCAACCCGACGGCCGCATCCCGATCTGGCTGCCGCCGGCCAAAAGGCTGCCCGACG
GCCTAGCATCGTATGTGTCCGTCGTGCGCATCCCCTGGAACGCGGCGGACACCGCACTGCTGGCTCCGCGTCCCGCGTTG
CTGGTCCGGCGGCGGCTCGACCTCGTCGCGTGGGCGACCGGGTTACCGGCGCTAGGACCAGAAGCATTACTTGTGCAAAT
CGCCACGCGCCCGGCCTCGTTCGGGCCGTGGGCCGACCTTGTCCCCCACCTTGACGACCTCGTCGCCGACTGCAGTGACG
AGCGCCTGGAGCGTCTACTGTCGGGCCGGCCGACATCGGCCTGGCAGCGTGCAAGCTACCTGCTGGACTCGGGCGGTGAA
CCGGCACGAGGCCAGGCGCTGCTGGCCAAGCGGCACACCGAAGTGATGCCGGTGACTCGATTCACCACCGCGCACAGCCG
CGACCGTGGCGAGAGTGTCTGGGCTCCCGAGTATCAGCTTGTCGACGAGCTCGTCGTACCGCTGCTGCGCGTGATCGGCA
AGGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References