Detailed information of TA system TA186602

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-sprA1AS/-
• Location: 27008..27156
• Replicon: plasmid unnamed1
• Accession: NZ_CP068080
• Organism: Staphylococcus carnosus strain FDAARGOS_1147

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: -
• Locus tag: I6J04_RS13090
• Protein ID: WP_011276848.1
• Coordinates: 27008..27103 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	27121..27156 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
I6J04_RS13060	23082..24074	+	993	WP_046100644.1	replication initiator protein A	-
I6J04_RS13065	24080..24286	+	207	Protein_20	protein rep	-
I6J04_RS13070	24997..25167	+	171	WP_160149154.1	hypothetical protein	-
I6J04_RS13075	25189..25617	+	429	WP_046100646.1	Hsp20/alpha crystallin family protein	-
I6J04_RS13080	25922..26119	+	198	WP_039069675.1	helix-turn-helix transcriptional regulator	-
I6J04_RS13085	26139..26681	+	543	WP_082080603.1	peptide deformylase	-
I6J04_RS13090	27008..27103	+	96	WP_011276848.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	27121..27156	+	36	NuclAT_0	-	Antitoxin
I6J04_RS13095	27363..29121	-	1759	Protein_26	retron Ec67 family RNA-directed DNA polymerase/endonuclease	-
I6J04_RS13100	29369..29977	+	609	WP_046100649.1	recombinase family protein	-
I6J04_RS13105	30346..32121	+	1776	WP_046100650.1	oleate hydratase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..33436	33436

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3623.38 Da
• Isoelectric Point: 9.5124

>T186602 WP_011276848.1 NZ_CP068080:27008-27103 [Staphylococcus carnosus]
MLEILVHITTTVISGCIIALFTHWLRNRKDK

Nucleotide

• Length: 96 bp

>T186602 NZ_CP089610:c2239397-2239053 [Mycobacterium tuberculosis]
GTGGTGATTAGTCGTGCCGAGATCTACTGGGCTGACCTCGGGCCGCCATCAGGCAGTCAGCCGGCGAAGCGCCGCCCGGT
GCTCGTAATCCAGTCAGATCCGTACAACGCAAGTCGCCTTGCCACTGTGATCGCAGCGGTGATCACGTCCAATACGGCGC
TGGCGGCAATGCCCGGCAACGTGTTCTTGCCCGCGACCACAACGCGACTGCCACGTGACTCGGTCGTCAACGTCACGGCG
ATTGTCACGCTCAACAAGACTGACCTCACCGACCGAGTTGGGGAGGTGCCAGCGAGCTTGATGCACGAGGTTGACCGAGG
ACTTCGTCGCGTACTGGACCTTTGA

Antitoxin

Nucleotide

• Length: 36 bp

>AT186602 NZ_CP068080:27121-27156 [Staphylococcus carnosus]
TACAAAAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin