Detailed information of TA system TA186593

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 1601867..1602126
• Replicon: chromosome
• Accession: NZ_CP068069
• Organism: Staphylococcus equorum strain FDAARGOS_1149

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: I6J06_RS07905
• Protein ID: WP_002511402.1
• Coordinates: 1602019..1602126 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF1
Locus tag	-
Coordinates	1601867..1602029 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
I6J06_RS07880	1597299..1598336	-	1038	WP_021339833.1	lactonase family protein	-
I6J06_RS07885	1598513..1598923	+	411	WP_002507169.1	YolD-like family protein	-
I6J06_RS07890	1599548..1599718	-	171	WP_002507168.1	hypothetical protein	-
I6J06_RS07895	1600213..1601253	+	1041	WP_021339984.1	choloylglycine hydrolase	-
I6J06_RS07900	1601561..1601731	+	171	WP_021339983.1	tyrosine-type recombinase/integrase	-
-	1601867..1602029	+	163	-	-	Antitoxin
I6J06_RS07905	1602019..1602126	-	108	WP_002511402.1	putative holin-like toxin	Toxin
I6J06_RS07910	1602492..1603343	-	852	WP_021339982.1	DUF4097 family beta strand repeat protein	-
I6J06_RS07915	1603340..1603900	-	561	WP_002511403.1	DUF1700 domain-containing protein	-
I6J06_RS07920	1603995..1604480	-	486	WP_021339981.1	hypothetical protein	-
I6J06_RS07925	1604651..1605211	+	561	WP_002507158.1	thioredoxin family protein	-
I6J06_RS07930	1605294..1606022	-	729	WP_002507157.1	ABC transporter permease subunit	-
I6J06_RS07935	1606022..1606894	-	873	WP_002507156.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (4-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3756.72 Da
• Isoelectric Point: 10.4997

>T186593 WP_002511402.1 NZ_CP068069:c1602126-1602019 [Staphylococcus equorum]
VVPIVEALHLMLGFGTFIVTLLGLVVAIVKLSHKK

Nucleotide

• Length: 108 bp

>T186593 NZ_CP089610:1693294-1693611 [Mycobacterium tuberculosis]
GTGAACGCGCCGTTGCGTGGTCAGGTCTATCGATGCGACCTCGGATACGGGGCCAAACCGTGGCTCATCGTCTCCAACAA
CGCCCGCAACCGTCACACCGCCGACGTGGTGGCTGTGCGCCTGACAACAACGCGGAGAACCATACCGACCTGGGTCGCCA
TGGGCCCCAGCGATCCATTGACCGGATACGTCAACGCGGACAACATCGAGACCCTCGGCAAAGACGAGCTCGGTGACTAC
CTCGGTGAGGTCACGCCGGCGACGATGAACAAAATCAACACGGCGCTCGCGACCGCGCTGGGGCTACCGTGGCCATGA

Antitoxin

Nucleotide

• Length: 163 bp

>AT186593 NZ_CP068069:1601867-1602029 [Staphylococcus equorum]
ATTTGATAATATTTTTATGTTGTGGTAATTTATATATAGAAAAAGGGCAACACACCATAAGTGTATCGCCCTAATGAGCC
CGTTAAAAAGACGGTGGCTGGAATTTAATAATGATTAAATAATCATCTCATCCTCGCCAAAGTTAGAGATGGTTATTTTT
TAT

Structures

Antitoxin