Detailed information of TA system TA186587

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 456921..457180
• Replicon: chromosome
• Accession: NZ_CP068063
• Organism: Staphylococcus equorum strain FDAARGOS_1150

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: I6J07_RS02325
• Protein ID: WP_002511402.1
• Coordinates: 456921..457028 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF1
Locus tag	-
Coordinates	457018..457180 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
I6J07_RS02295	452163..453035	+	873	WP_002507156.1	ABC transporter ATP-binding protein	-
I6J07_RS02300	453035..453763	+	729	WP_002507157.1	ABC transporter permease subunit	-
I6J07_RS02305	453846..454406	-	561	WP_103170485.1	thioredoxin family protein	-
I6J07_RS02310	454577..455062	+	486	WP_069819006.1	hypothetical protein	-
I6J07_RS02315	455156..455716	+	561	WP_002511403.1	DUF1700 domain-containing protein	-
I6J07_RS02320	455713..456564	+	852	WP_103170566.1	DUF4097 family beta strand repeat protein	-
I6J07_RS02325	456921..457028	+	108	WP_002511402.1	putative holin-like toxin	Toxin
-	457018..457180	-	163	-	-	Antitoxin
I6J07_RS02330	457486..458229	+	744	WP_069827917.1	HAD-IIB family hydrolase	-
I6J07_RS02335	458249..458404	+	156	WP_002507163.1	hypothetical protein	-
I6J07_RS02340	458514..458807	+	294	WP_040762580.1	hypothetical protein	-
I6J07_RS02345	458785..459435	+	651	WP_103169961.1	cytochrome P450	-
I6J07_RS02350	460018..461058	-	1041	WP_103169960.1	acyl-CoA--6-aminopenicillanic acid acyltransferase	-
I6J07_RS02355	461553..461723	+	171	WP_002507168.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (4-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3756.72 Da
• Isoelectric Point: 10.4997

>T186587 WP_002511402.1 NZ_CP068063:456921-457028 [Staphylococcus equorum]
VVPIVEALHLMLGFGTFIVTLLGLVVAIVKLSHKK

Nucleotide

• Length: 108 bp

>T186587 NZ_CP089610:c1235999-1235688 [Mycobacterium tuberculosis]
ATGCGACCTATCCACATCGCACAGCTTGACAAGGCTAGACCCGTCCTGATCCTTACCCGCGAGGTCGTACGTCCGCACCT
CACGAACGTCACCGTCGCCCCGATCACGACAACCGTGCGTGGGCTAGCCACCGAAGTCCCGGTAGACGCGGTGAACGGGC
TGAATCAACCGTCAGTCGTCAGCTGCGACAACACCCAAACGATCCCGGTGTGTGACCTTGGTCGTCAAATCGGCTACCTG
CTCGCGTCGCAGGAGCCGGCTCTAGCCGAGGCCATCGGCAACGCGTTCGACCTCGATTGGGTGGTGGCATAG

Antitoxin

Nucleotide

• Length: 163 bp

>AT186587 NZ_CP068063:c457180-457018 [Staphylococcus equorum]
ATTTGATAATATTTTTATGTTGTGGTAATTTATATATAGAAAAAGGGCAACACACCATAAGTGTATCGCCCTAATGAGCC
CGTTAAAAAGACGGTGGCTGGAATTTAATAATGATTAAATAATCATCTCATCCTCGCCAAAGTTAGAGATGGTTATTTTT
TAT

Structures

Antitoxin