Detailed information of TA system TA186327

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yefM-yoeB (relBE)/YoeB-YefM
• Location: 5321817..5322385
• Replicon: chromosome
• Accession: NZ_CP067420
• Organism: Skermanella sp. TT6

Toxin (Protein)

• Gene name: yoeB
• Uniprot ID: -
• Locus tag: IGS68_RS24825
• Protein ID: WP_201075119.1
• Coordinates: 5322116..5322385 (+)
• Length: 90 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: IGS68_RS24820
• Protein ID: WP_201075117.1
• Coordinates: 5321817..5322119 (+)
• Length: 101 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (6-89)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-74)

Sequences

Toxin

Protein

• Length: 90 a.a.
• Molecular weight: 10772.06 Da
• Isoelectric Point: 8.0245

>T186327 WP_201075119.1 NZ_CP067420:5322116-5322385 [Skermanella sp. TT6]
MTRLAWTDAAWEDYTWWQENDRKTARRINELIKSTLRTPFDGVGKPEPLRGDWAGWWSRRITLEHRLVYRNFGNGDDETL
IIAQCRYHY

Nucleotide

• Length: 270 bp

>T186327 NZ_CP089325:3985639-3985857 [Klebsiella pneumoniae]
ATGTCTGATAAGCCATTAACTAAAACAGACTATTTGATGCGCTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGCGT
CATTGAAAAAAATAAATATGAACTGTCTGATAATGAGCTGGCGGTATTTTACTCAGCTGCCGACCATCGTCTGGCGGAAC
TGACCATGAATAAGCTATACGATAAAATCCCGACTTCTGTCTGGAAATTTATCCGCTAA

Antitoxin

Protein

• Length: 101 a.a.
• Molecular weight: 11192.48 Da
• Isoelectric Point: 4.2972

>AT186327 WP_201075117.1 NZ_CP067420:5321817-5322119 [Skermanella sp. TT6]
MGHVSYTELRQNLARYMDEVCDSNAPLVVTRQNARPVVMISQDEYESMAATLHLIKSPRNALRLIESMEDAKAGRVSERG
LIEVDDEAETDLRTGDGEPD

Nucleotide

• Length: 303 bp

>AT186327 NZ_CP089325:3985238-3985612 [Klebsiella pneumoniae]
ATGGACGAATACTCGCCAAAAAGACATGATATTGCACAGCTACGCTTTCTCTGCGAAACGCTGTATCATGACTGCCTTGC
AAACCTGGAAGAGAGCAACCATGGCTGGGTCAACGACCCGACGTCGGCTGTCAATCTCCAGTTAAATGAATTGATCGAGC
ACATTGCCACATTCGCTCTTAATTATAAAATTAAGTATGCAGAGGATAATAAGCTGATCGCTCAGGTTGACGAATATCTG
GACGACACTTTTACGTTGTTCAGTAACTACGGCATTAACTCTACGGATTTGCAAAAGTGGAAAAAATCCGGTAACCGACT
ATTTCGTTGCTTTGTCAACGCCAGCCGGGAAAACCCGGCCAGTCTATCGTGTTAG