Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 2863000..2863508 Replicon chromosome
Accession NZ_CP067394
Organism Cryobacterium sp. SO1

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag BJQ95_RS13510 Protein ID WP_130178713.1
Coordinates 2863248..2863508 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag BJQ95_RS13505 Protein ID WP_130178714.1
Coordinates 2863000..2863251 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BJQ95_RS13480 2858923..2859747 + 825 WP_130178718.1 PhnD/SsuA/transferrin family substrate-binding protein -
BJQ95_RS13485 2859750..2860739 + 990 WP_205750202.1 radical SAM protein -
BJQ95_RS13490 2860757..2861302 + 546 WP_130178717.1 DoxX family protein -
BJQ95_RS13495 2861299..2861679 + 381 WP_130178716.1 hypothetical protein -
BJQ95_RS13500 2861938..2862570 + 633 WP_130178715.1 HNH endonuclease family protein -
BJQ95_RS13505 2863000..2863251 + 252 WP_130178714.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
BJQ95_RS13510 2863248..2863508 + 261 WP_130178713.1 Txe/YoeB family addiction module toxin Toxin
BJQ95_RS13515 2863656..2865473 - 1818 WP_130178712.1 glycoside hydrolase family 15 protein -
BJQ95_RS13520 2865470..2866759 - 1290 WP_130178711.1 bifunctional alpha/beta hydrolase/OsmC family protein -
BJQ95_RS13525 2866843..2866980 + 138 WP_256041383.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(7-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10234.53 Da        Isoelectric Point: 8.4495

>T186238 WP_130178713.1 NZ_CP067394:2863248-2863508 [Cryobacterium sp. SO1]
VSRTIAFDPNGWEDYVYWQTQDRKTLKRINQLITDTLRDPFAGIGKPEPLRHVLSGAWSRRIDDTNRLVYYVTDDRIVIL
QAREHY

Download         Length: 261 bp

>T186238 NZ_CP089301:c309073-308804 [Novosphingobium kaempferiae]
ATGAAGATCGTCTTCGCTTCCCGCGCCTGGGAAGATTATCAACATTGGGTAGCGAACGATCGCGCGACGCTGGAGCGCCT
AAACGCGCTGGTCGAGCAATGTCGGCACACTCCGTTCAAGGGCACCGGCAAGCCCGAGCCGCTCAAGGGCGAATTGCAGG
GCTGGTGGTCCCGGCGGATCAATCAGGCGGATCGGCTGGTCTATCGTGTCGCGGGCACCGGTGCCGAGCAGCGGCTCGAA
ATCGCGCAATGCCGGTTCCATTACGCCTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9247.37 Da        Isoelectric Point: 4.8000

>AT186238 WP_130178714.1 NZ_CP067394:2863000-2863251 [Cryobacterium sp. SO1]
MSAITATEARKSLFGLIQQVNDDHTAIEVVSRHGNAVILSKEDYDALTETAFLLRNPANAERLLAAIERVRRGEFEQHDL
LDA

Download         Length: 252 bp

>AT186238 NZ_CP089301:c309335-309081 [Novosphingobium kaempferiae]
ATGGATGTGCTCTCGTTCTCCGAAGCGCGCGCCAATTTCAAGGCGCTGATGGATCATGTGGTGGACGATCGTTCGCCCGT
GATCGTCACGCGCCAGAAGGCGGAAGCGGTCGTGATGGTTTCCCTGTCCGACTGGAACGCCATGGCCGAAACCATGCATC
TGCTTTCCACGCCCGCGAACTCGCAGCGGCTCCGCGACGCTGTTCGGGAATTCGATATGGGCGAGGGCGAGGAACACGAT
CTCGTCCAGCCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References