185706

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 1611589..1612103 Replicon chromosome
Accession NZ_CP067088
Organism Limosilactobacillus fermentum strain B44

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag JIO03_RS08090 Protein ID WP_200548460.1
Coordinates 1611589..1611852 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag JIO03_RS08095 Protein ID WP_035437201.1
Coordinates 1611849..1612103 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JIO03_RS08070 1606761..1607267 - 507 WP_200548459.1 prolyl-tRNA synthetase associated domain-containing protein -
JIO03_RS08075 1607343..1608087 + 745 Protein_1544 dimethylargininase -
JIO03_RS08080 1608475..1609872 + 1398 WP_024271998.1 sodium:proton antiporter -
JIO03_RS08085 1610298..1611419 + 1122 WP_021350111.1 PTS sugar transporter subunit IIC -
JIO03_RS08090 1611589..1611852 - 264 WP_200548460.1 Txe/YoeB family addiction module toxin Toxin
JIO03_RS08095 1611849..1612103 - 255 WP_035437201.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
JIO03_RS08100 1612334..1613686 - 1353 WP_200548461.1 transposase -
JIO03_RS08105 1614068..1615438 - 1371 WP_200548462.1 FAD-dependent oxidoreductase -
JIO03_RS08110 1615665..1616096 + 432 Protein_1551 IS30 family transposase -
JIO03_RS08115 1616181..1616468 + 288 WP_003688751.1 transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(4-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-55)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10313.00 Da        Isoelectric Point: 10.4139

>T185706 WP_200548460.1 NZ_CP067088:c1611852-1611589 [Limosilactobacillus fermentum]
MSYAIKLKRSANRDLKKIKGSYLEKSFLQIIEQLRKDPLAPNQGFEKLVPPIKGFYSRRINIQHRLVYKVDQDTQTVIIY
SAWSHYE

Download         Length: 264 bp

>T185706 NZ_CP089000:c199200-198757 [Klebsiella pneumoniae]
ATGAAGAAAACCTGGATGCTCGACACTAACATCTGCTCGTTCATCATGCGCGAGCAGCCGGCAGCGGTGCTGAAGCGCCT
GGAACAGGCGGTGCTGCGCGGTGATCGCATCGTGGTCTCGGCCGTGACGTATGCCGAGATGCGCTTCGGCGCCACCGGCC
CGAAGGCCTCGCCGCGCCATATTCAGCTGGTCGACGCGTTCTGCGCGCGCCTCGATGCCATCCTGCCCTGGGACCGGGCC
GCGGTGGACGCCACGACGGACATCCGGGTGGCGCTGCGCCTCGCCGGGACGCCGATCGGCCCGAACGACACGGCCATTGC
TGGGCACGCTATCGCGGCCGGCGCCGTCCTAGTGACGAACAATGTGAGAGAGTTTGAGCGGGTGCCGGGTCTGGTGCTGG
AAGACTGGGTGAAGAAAGCCGCTCTCTGCAGGGTAATTTCTTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9773.05 Da        Isoelectric Point: 4.4237

>AT185706 WP_035437201.1 NZ_CP067088:c1612103-1611849 [Limosilactobacillus fermentum]
MDQIVTPTQARKDLFKIIKRINENNEPVVIKPTRADEKSVVVIGEDDWKAIQETLFLVNHGVDKQIKERENEPLDDFDDV
WGQL

Download         Length: 255 bp

>AT185706 NZ_CP089000:c199427-199197 [Klebsiella pneumoniae]
ATGCGCACAGTTTCGATATTTAAAAACGGCAATAACCGCGCCATCCGTCTGCCCCGGGACCTGGATTTTGACGGCGTCAG
CGAGCTGGAGATCGTCCGGGAAGGGGACAGCATCATTCTGCGTCCCGTCCGGCCGACCTGGGGCTCGTTCGCGCAGCTGG
ACAGGGCCGCTCCGGACTTTATGGCGGAGCGTGAGGATGTGGTCAGCGATGAAGGACGCTTTGAGCCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References