Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 174085..174784 Replicon plasmid pPlas1
Accession NZ_CP067058
Organism Rahnella aceris strain ZF458

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag JHW33_RS23265 Protein ID WP_200227412.1
Coordinates 174085..174381 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID A0A0H3FHC0
Locus tag JHW33_RS23270 Protein ID WP_013578313.1
Coordinates 174383..174784 (+) Length 134 a.a.

Genomic Context


JHW33_RS23240JHW33_RS23245JHW33_RS23250JHW33_RS23255JHW33_RS23260JHW33_RS23265JHW33_RS23270JHW33_RS23275JHW33_RS23280JHW33_RS23285JHW33_RS23290JHW33_RS23295JHW33_RS23300JHW33_RS23305JHW33_RS23310JHW33_RS23315JHW33_RS23235
Location: 171406..171912 (507 bp)
Type: Others
Protein ID: WP_041689224.1
Location: 171954..172154 (201 bp)
Type: Others
Protein ID: WP_013578318.1
Location: 172985..173227 (243 bp)
Type: Others
Protein ID: WP_013578317.1
Location: 173230..173535 (306 bp)
Type: Others
Protein ID: WP_013578316.1
Location: 173532..173990 (459 bp)
Type: Others
Protein ID: WP_200227410.1
Location: 174085..174381 (297 bp)
Type: Toxin
Protein ID: WP_200227412.1
Location: 174383..174784 (402 bp)
Type: Antitoxin
Protein ID: WP_013578313.1
Location: 175147..175338 (192 bp)
Type: Others
Protein ID: WP_200227414.1
Location: 175449..175823 (375 bp)
Type: Others
Protein ID: WP_200227417.1
Location: 175886..176227 (342 bp)
Type: Others
Protein ID: WP_200227579.1
Location: 176316..176561 (246 bp)
Type: Others
Protein ID: WP_200227420.1
Location: 176612..176986 (375 bp)
Type: Others
Protein ID: WP_147423476.1
Location: 177212..177349 (138 bp)
Type: Others
Protein ID: WP_200227422.1
Location: 178028..178378 (351 bp)
Type: Others
Protein ID: WP_200227424.1
Location: 178429..178566 (138 bp)
Type: Others
Protein ID: WP_200227427.1
Location: 178578..179201 (624 bp)
Type: Others
Protein ID: WP_200227433.1
Location: 170057..171013 (957 bp)
Type: Others
Protein ID: WP_200227407.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
JHW33_RS23235170057..171013-957WP_200227407.1IS110 family transposase-
JHW33_RS23240171406..171912+507WP_041689224.1antirestriction protein ArdA-
JHW33_RS23245171954..172154+201WP_013578318.1hypothetical protein-
JHW33_RS23250172985..173227+243WP_013578317.1DUF905 family protein-
JHW33_RS23255173230..173535+306WP_013578316.1hypothetical protein-
JHW33_RS23260173532..173990+459WP_200227410.1hypothetical protein-
JHW33_RS23265174085..174381+297WP_200227412.1type II toxin-antitoxin system MqsR family toxinToxin
JHW33_RS23270174383..174784+402WP_013578313.1type II toxin-antitoxin system MqsA family antitoxinAntitoxin
JHW33_RS23275175147..175338+192WP_200227414.1hypothetical protein-
JHW33_RS23280175449..175823+375WP_200227417.1hypothetical protein-
JHW33_RS23285175886..176227+342WP_200227579.1hypothetical protein-
JHW33_RS23290176316..176561+246WP_200227420.1hypothetical protein-
JHW33_RS23295176612..176986+375WP_147423476.1hypothetical protein-
JHW33_RS23300177212..177349+138WP_200227422.1hypothetical protein-
JHW33_RS23305178028..178378+351WP_200227424.1hypothetical protein-
JHW33_RS23310178429..178566+138WP_200227427.1hypothetical protein-
JHW33_RS23315178578..179201+624WP_200227433.1hypothetical protein-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid--1..188256188256


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(5-97)

Antitoxin

(3-47)


Sequences


Toxin        


Download         Length: 99 a.a.        Molecular weight: 10770.41 Da        Isoelectric Point: 7.8798

>T185651 WP_200227412.1 NZ_CP067058:174085-174381 [Rahnella aceris]
MEKKTPHTRLHIVQGFVAAGKVKATNTALNGADDLGLTFDDMCSAILGLTAADFFKSMTTYNDHTVWQDVYRPKLSCGDV
YLKLTVSNGVLIVSFKEK

Download         Length: 297 bp

>T185651 NZ_CP088985:c4397378-4396845 [Klebsiella pneumoniae]
ATGGAGCAGCAACTGACGATTGAGATGATTGCCGATGCGTTCAGCTACGATATCACTGGATTTGATTGCGGCGAGGAAGC
GCTGAATACGTTTTTAAAAGAGCACCTCAAGCGGCAGCACGATGGACAAATCTTAAGGGGTTATGCGCTGGTCTCCGGGG
ATACCGTTCCCAGGTTGCTGGGTTATTACACCTTATCGGGGAGTTGTTTCGAGCGAGGCATGTTGCCGTCTAAAACTCAG
CAAAAGAAAATCCCGTATCAAAATGCGCCAAGCGTAACCCTCGGGCGGCTGGCCATTGATAAATCTGTTCAGGGGCAGGG
CTGGGGAGAGATGTTGGTTGCCCATGCGATGCGAGTGGTGTGGGGAGCGTCTAAAGCCGTTGGTATCTACGGATTGTTTG
TTGAAGCCCTTAATGAGAAGGCTAAAGCATTCTATCTTCGTCTGGGGTTTATACAGCTCGTGGATGAAAATAGTAACTTA
CTGTTTTATCCGACCAAATCGATTGAACAGCTCTTTACTGACGATGAGTCATAA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14922.38 Da        Isoelectric Point: 8.4858

>AT185651 WP_013578313.1 NZ_CP067058:174383-174784 [Rahnella aceris]
MKCSVCGGAELEFGIKKVPYSFRGRKTVIEAEGDHCPACGEVVMDREQSMAYMAKVKSFKAKVIAETIEPEYIIQVRKKL
ELTQKEASEIFGGGVNAFSRYEKGKAQPHPSIIKLLRVLDHHPELLDEVRKQA

Download         Length: 402 bp

>AT185651 NZ_CP088985:c4397655-4397389 [Klebsiella pneumoniae]
ATGCCCGCACTTAAAAAGCAGCGTATAGATTTGAGATTAACCGATGATGATAAGAGCATCATCGAGGAAGCTGCGGCAAT
TTCGAATCAGACGATTACCCAGTTTGTGGTTGCCAGTGCCTCAGAACGTGCTGCGGAAGTGATTGAGCAGCACCGCAGAA
TGGTCCTCAATGAGCAATCATGGAGCCTGGTGATGGAGGCGATTACCCAACCGCCAGCCCCGAATGATCGACTGAAACGT
GCAGCGAAGCGTCTACAAACCAGGTAA

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
AlphaFold DBA0A0H3FHC0

References