Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 3736134..3736961 Replicon chromosome
Accession NZ_CP067057
Organism Rahnella aceris strain ZF458

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag JHW33_RS17035 Protein ID WP_037033823.1
Coordinates 3736134..3736610 (-) Length 159 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID A0A0H3F4N7
Locus tag JHW33_RS17040 Protein ID WP_013573435.1
Coordinates 3736617..3736961 (-) Length 115 a.a.

Genomic Context

JHW33_RS17005JHW33_RS17010JHW33_RS17015JHW33_RS17020JHW33_RS17035JHW33_RS17040JHW33_RS17045JHW33_RS17050JHW33_RS17055JHW33_RS17060JHW33_RS17065JHW33_RS17070
Location: 3731208..3732653 (1446 bp)
Type: Others
Protein ID: WP_200223571.1
Location: 3732724..3733182 (459 bp)
Type: Others
Protein ID: WP_013573431.1
Location: 3733317..3733739 (423 bp)
Type: Others
Protein ID: WP_013573432.1
Location: 3734011..3735690 (1680 bp)
Type: Others
Protein ID: WP_037033825.1
Location: 3736134..3736610 (477 bp)
Type: Toxin
Protein ID: WP_037033823.1
Location: 3736617..3736961 (345 bp)
Type: Antitoxin
Protein ID: WP_013573435.1
Location: 3737043..3737372 (330 bp)
Type: Others
Protein ID: WP_037033821.1
Location: 3737341..3737577 (237 bp)
Type: Others
Protein ID: WP_037033819.1
Location: 3737789..3739168 (1380 bp)
Type: Others
Protein ID: WP_200223572.1
Location: 3739188..3739970 (783 bp)
Type: Others
Protein ID: WP_200223573.1
Location: 3739970..3740836 (867 bp)
Type: Others
Protein ID: WP_134706483.1
Location: 3740829..3741764 (936 bp)
Type: Others
Protein ID: WP_112197519.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
JHW33_RS170053731208..3732653+1446WP_200223571.1alpha/beta hydrolase-
JHW33_RS170103732724..3733182+459WP_013573431.1MarR family transcriptional regulator-
JHW33_RS170153733317..3733739+423WP_013573432.1organic hydroperoxide resistance protein-
JHW33_RS170203734011..3735690+1680WP_037033825.1kdo(2)-lipid A phosphoethanolamine 7''-transferase-
JHW33_RS170353736134..3736610-477WP_037033823.1type II toxin-antitoxin system YhaV family toxinToxin
JHW33_RS170403736617..3736961-345WP_013573435.1type II toxin-antitoxin system PrlF family antitoxinAntitoxin
JHW33_RS170453737043..3737372-330WP_037033821.1type II toxin-antitoxin system RelE/ParE family toxin-
JHW33_RS170503737341..3737577-237WP_037033819.1ParD-like family protein-
JHW33_RS170553737789..3739168-1380WP_200223572.1MmgE/PrpD family protein-
JHW33_RS170603739188..3739970-783WP_200223573.1ABC transporter ATP-binding protein-
JHW33_RS170653739970..3740836-867WP_134706483.1ABC transporter ATP-binding protein-
JHW33_RS170703740829..3741764-936WP_112197519.1ABC transporter permease-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(13-148)

Antitoxin

SpoVT-AbrB domain

(15-53)


Sequences

Toxin        


Download         Length: 159 a.a.        Molecular weight: 18516.32 Da        Isoelectric Point: 9.9550

>T185646 WP_037033823.1 NZ_CP067057:c3736610-3736134 [Rahnella aceris]
MHNQAMEINGWTLLAHPLILQQIQALTDQVVLLRRKDPAGYKSKNATKRLAAINKLMFDVIPQDPARVEFRQGDTLGGEF
SHWFRAKFFQQYRLFFRYNLKSRIIIYAWVNDDKELRAYESKTDAYRMFRKMLKSGEPPDNWQALCEASGKVAAEEFP

Download         Length: 477 bp

>T185646 NZ_CP088985:c963088-962678 [Klebsiella pneumoniae]
GTGGTCCTGTGGCAATCTGATCTCCGTATCTCCTGGCGCGCGCAGTGGTTTTCCCTGCTGCTTCACGGCGTGGTGGCGGC
CCTGGTGCTGTTGGTTCCCTGGCCGCTGAGCTATACCCCGATCTGGCTGCTGCTGCTGTCGCTGGTGGTCTTCGACTGCG
TGCGCAGCCAGCGGCGGATCCATGCCCGTCGCGGGGAGATAAAACTGCTCACCGATTCCCGTCTTCGCTGGCAAAACGCC
GAATGGGAAATCCTCGGGACGCCGTGGGTTATCAATAGCGGTATGCTGCTGCGTTTGCGCCATGTCGATACCCGGCGCGG
ACAGCATCTTTGGCTGGCGGCGGACAGCATGGACGCCGGAGAGTGGCGCGATCTGCGCCGGCTGGTGCTGCAAAAACCGG
CGCAGGAGTAA

Antitoxin


Download         Length: 115 a.a.        Molecular weight: 12701.48 Da        Isoelectric Point: 4.3324

>AT185646 WP_013573435.1 NZ_CP067057:c3736961-3736617 [Rahnella aceris]
MSASALWGIKFEAESKVTRRFQTTIPATIRKALNLTENDRIQYKILPDGQVVISRQLEEAEDPVISAFLGFVAKDMLNNP
ENMQPVTLSLHEKINVLTAGMAIDLESPLSDDDE

Download         Length: 345 bp

>AT185646 NZ_CP088985:c963335-963069 [Klebsiella pneumoniae]
ATGGACATTAACAATAAAGCACGTATCCACTGGGCATGCCGCCGCGGGATGCGCGAACTCGACATCTCCATCATGCCGTT
CTTTGAGTATGAGTACGATACCCTCAGCGACGCTGACAAACAGCTGTTCATTCGCCTGCTGGAAAATGACGATCCGGATC
TGTTCAACTGGCTGATGAACCACGGCAAACCGGCCGATGCGGAGCTGCAGCGGATGGTAACCTTAATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A0H3F4N7

References