185610

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DinJ-YafQ (relBE)/YafQ-DinJ
Location 474583..475126 Replicon chromosome
Accession NZ_CP067042
Organism Lacticaseibacillus rhamnosus strain B6

Toxin (Protein)


Gene name yafQ Uniprot ID -
Locus tag JGE02_RS02265 Protein ID WP_005709630.1
Coordinates 474583..474870 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID -
Locus tag JGE02_RS02270 Protein ID WP_005714439.1
Coordinates 474854..475126 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JGE02_RS02235 469831..470199 - 369 WP_005686376.1 PTS-dependent dihydroxyacetone kinase phosphotransferase subunit DhaM -
JGE02_RS02240 470233..470814 - 582 WP_005709619.1 dihydroxyacetone kinase subunit L -
JGE02_RS02245 470801..471820 - 1020 WP_005709622.1 dihydroxyacetone kinase subunit DhaK -
JGE02_RS02250 472014..472442 - 429 WP_005714437.1 OsmC family protein -
JGE02_RS02255 472553..472732 - 180 WP_005709626.1 hypothetical protein -
JGE02_RS02260 472950..474359 - 1410 WP_005714438.1 3'-5' exonuclease -
JGE02_RS02265 474583..474870 - 288 WP_005709630.1 type II toxin-antitoxin system YafQ family toxin Toxin
JGE02_RS02270 474854..475126 - 273 WP_005714439.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
JGE02_RS02275 475240..475533 + 294 WP_005684269.1 metalloregulator ArsR/SmtB family transcription factor -
JGE02_RS02280 475615..476778 + 1164 WP_005709634.1 MFS transporter -
JGE02_RS02285 476941..478314 - 1374 WP_005714442.1 MFS transporter -
JGE02_RS02290 478427..479527 + 1101 WP_005709638.1 metalloregulator ArsR/SmtB family transcription factor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(4-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(6-67)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10888.77 Da        Isoelectric Point: 10.9032

>T185610 WP_005709630.1 NZ_CP067042:c474870-474583 [Lacticaseibacillus rhamnosus]
MMLTINRTRTFKRQFKHLLRQGKDMTKLATAIDTLQRQDRVKLASLHDHALKGAHSGERALRVAPDWLLVYKVDAEALIL
MLLATGTHRDTLNIE

Download         Length: 288 bp

>T185610 NZ_CP088955:478283-478672 [Acinetobacter calcoaceticus]
TTGATAAAAGAATTGAATTTTGAGCTGAAATATAGTCGTTTCTCGATAATATTTCAGCTTTTTATTGGCTTGAGTTTAGC
AATCTTACTTTATCAATTGTTATCACCCATTGGGTGGTTGATTGCTTTCATCCTTTTATCTATTAGTTTTCTATTTTCTT
TAAGACAATCACGAATTTCTCAAATTGCATATTTAGACCAAAAATCGTGGTCAATTGCATACTCCTCACAAAAGATAATT
TCTCGTGTGGAAATTTCTAAAATAATTGATTATCAGTTGTTTATAGTTATTTATCTTGAGGGGGCGCCTATAAAGGTAGC
CATAATTTGGTTTGATCAACTTCCTTTGCAGCATTGGAAAAAGCTAAAAGTCTTACAGAAACTTCATTAA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10073.49 Da        Isoelectric Point: 5.1154

>AT185610 WP_005714439.1 NZ_CP067042:c475126-474854 [Lacticaseibacillus rhamnosus]
METKSRISVRIDTKTKERALHVLNSMGLDMSSAINMYLKRIGDTGELPFTPEMSFADQLQAAEADVKAGRTKSFKTVDAL
MKDLYNDVDD

Download         Length: 273 bp

>AT185610 NZ_CP088955:478019-478276 [Acinetobacter calcoaceticus]
ATGTCTGACGAAATGACCTTGGAAGAACGTAAAGTAATTTATCGAGCACGCCGCGGCTTAAAAGAAATTGACGTCTATTT
TGACCCTTATGTAAAAAACTATTATCTAAAAGCGGATTCGGCAGAGAAGGCCTTATTTGCAGAGTTAGTTGAACAGGAAG
ATCCTGATTTACTCGATTGGTTCATGGAAGTTTCTGAACCTCCACGCACAGAGTTACGTGAATTTATTTATAAATTAAAA
CAGTACGTTCATGGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References