Detailed information of TA system TA185579

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-sprA1AS/-
• Location: 1001751..1001912
• Replicon: chromosome
• Accession: NZ_CP067014
• Organism: Staphylococcus pasteuri strain FDAARGOS_1069

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: -
• Locus tag: I6I26_RS05005
• Protein ID: WP_107999723.1
• Coordinates: 1001751..1001846 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1001878..1001912 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
I6I26_RS04995	997686..1000619	+	2934	WP_126567448.1	AAA family ATPase	-
I6I26_RS05000	1000619..1001560	+	942	WP_017638040.1	3'-5' exoribonuclease YhaM	-
I6I26_RS05005	1001751..1001846	+	96	WP_107999723.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	1001878..1001912	-	35	-	-	Antitoxin
I6I26_RS05010	1002006..1002998	-	993	WP_126568313.1	peptidylprolyl isomerase	-
I6I26_RS05015	1003181..1003738	-	558	WP_029056283.1	DUF3267 domain-containing protein	-
I6I26_RS05020	1003933..1004304	-	372	WP_017638293.1	YtxH domain-containing protein	-
I6I26_RS05025	1004382..1004807	-	426	WP_017638294.1	HIT family protein	-
I6I26_RS05030	1004939..1005679	+	741	WP_017638295.1	ABC transporter ATP-binding protein	-
I6I26_RS05035	1005672..1006895	+	1224	WP_126567503.1	ABC transporter permease	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• HicA mRNA interferase family (3-58)

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3656.34 Da
• Isoelectric Point: 8.0878

>T185579 WP_107999723.1 NZ_CP067014:1001751-1001846 [Staphylococcus pasteuri]
MSEIFVHIMTTVISGCIVTLFAHWLRHRNDK

Nucleotide

• Length: 96 bp

>T185579 NZ_CP088921:1238812-1238988 [Rhodanobacter denitrificans]
ATGAAGTACAGCGAGTTCCAGCGGTGGCTCAGGCAGCAGGGAGTGAGCTTCGAGCCCGGCAAGGGCAGCCACCAGCTGGC
GCGCTACAGAGGCCGGACTTCCGTCTTTCCCTTCCACGGATCGAAAGAGATGCCCGAGCCGCTGCGCAAGAAGATCCTGA
AGGACCTGGGTCTTTGA

Antitoxin

Nucleotide

• Length: 35 bp

>AT185579 NZ_CP067014:c1001912-1001878 [Staphylococcus pasteuri]
ACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin