Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/Tad-HTH_37
Location 684246..684858 Replicon chromosome
Accession NZ_CP066770
Organism Burkholderia anthina strain BJQ0011

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag JFN94_RS19340 Protein ID WP_124829757.1
Coordinates 684520..684858 (-) Length 113 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag JFN94_RS19335 Protein ID WP_124829679.1
Coordinates 684246..684533 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JFN94_RS19305 679718..680539 + 822 WP_124829683.1 SDR family oxidoreductase -
JFN94_RS19310 680657..681436 - 780 WP_175751142.1 5'/3'-nucleotidase SurE -
JFN94_RS19315 681646..681945 - 300 WP_124829758.1 AzlD family protein -
JFN94_RS19320 681938..682675 - 738 WP_124829681.1 AzlC family ABC transporter permease -
JFN94_RS19325 682799..683257 + 459 WP_098554569.1 Lrp/AsnC family transcriptional regulator -
JFN94_RS19330 683472..684041 + 570 WP_124829680.1 hypothetical protein -
JFN94_RS19335 684246..684533 - 288 WP_124829679.1 helix-turn-helix transcriptional regulator Antitoxin
JFN94_RS19340 684520..684858 - 339 WP_124829757.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JFN94_RS19345 685089..685721 - 633 WP_124829678.1 LysE family translocator -
JFN94_RS19350 685898..686758 - 861 WP_124829677.1 PASTA domain-containing protein -
JFN94_RS19355 686809..687141 - 333 WP_124829676.1 DUF2322 family protein -
JFN94_RS19360 687442..687768 + 327 WP_199569003.1 thioredoxin family protein -
JFN94_RS19365 687779..688198 + 420 WP_124829674.1 secondary thiamine-phosphate synthase enzyme YjbQ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(20-105)

Antitoxin

Cro/C1-type helix-turn-helix domain

(37-90)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 12950.19 Da        Isoelectric Point: 10.5584

>T185006 WP_124829757.1 NZ_CP066770:c684858-684520 [Burkholderia anthina]
MATAYEIQFFNARVETGVITLPKTLLARFFALADRMEQYGPNLREPHTQSMGNGLYEMRLKGAEGIARVFYCAIVDRRIV
MLHCFVKKTQKTPRKKLETARRRLKEVQDGNV

Download         Length: 339 bp

>T185006 NZ_CP087863:361280-361672 [Moraxella bovis]
ATGAAATATTTGCTGGACACCAATGCAGTCATTGCGATTTTGAATGCCAGTGAACGATTTTTGACCACGCTAGAACGGCA
TAAAGAGCGTGAAATTGCCATCTCGTCAATTGTTTTGTCGGAGCTGTATTATGGGGCGTACAAAAGCCAAAAAACCGCCC
AAAACCTTGAAAAAATCAATCTACTACCCTTTGAAGTGTTGCAATTTAATTCACAGGACGCTGATAAGGCTGGCGAAATT
GGTGCAACCCTAGAAAGGCGTGGCACACCCATTGGTTCTTATGACACGCTGATTGCAGGGCAAGCGATTGCCAATGATTT
GATTGTTATTACTGACAATGTGCGAGAATTTCTCCGAGTGGACGGTTTGCAAATTGAAAGTTGGTTAAAATAA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10444.01 Da        Isoelectric Point: 9.9572

>AT185006 WP_124829679.1 NZ_CP066770:c684533-684246 [Burkholderia anthina]
MATYKALRERALSDPEVHAEYERLNREDLTLLDAMLAARRDAGLSQADVAKRMGTKAPAVTRLERALATGQHSPSIDTLR
KYATACGKKLVISFA

Download         Length: 288 bp

>AT185006 NZ_CP087863:361020-361283 [Moraxella bovis]
ATGCGCCAAACTGCCACCGCAAAATTATTTTGGACTGGCAACAGTCAAGCCGTTCGCTTACCCAAAGCCTTTCGTTTTGA
AGGCACGGAAGTGCGTATCAAAAAACAAGGACGACAAGTGATTATTGAGCCAGCAGAGACCCAAGATTGGGCGTGGCTGG
ACAAATTGCGAGCAATGCCAAAAGATGACAGTTTTGAAGAAGCCATTTTGGAAGGTCGCCAAAATTTAAAAGCCGATGAA
CGAGATTGGGGTGCATTTGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References