Detailed information of TA system TA184839

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): holin-SprF1/-
• Location: 1853846..1854227
• Replicon: chromosome
• Accession: NZ_CP066726
• Organism: Staphylococcus xylosus strain TMW 2.1324

Toxin (Protein)

• Gene name: holin
• Uniprot ID: -
• Locus tag: JGY90_RS14255
• Protein ID: WP_263855845.1
• Coordinates: 1853846..1853968 (-)
• Length: 41 a.a.

Antitoxin (RNA)

Gene name	SprF1
Locus tag	-
Coordinates	1854065..1854227 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JGY90_RS08970 (JGY90_08930)	1849426..1851309	-	1884	WP_069794480.1	DUF5776 domain-containing protein	-
JGY90_RS08975 (JGY90_08935)	1851831..1852079	-	249	WP_225518030.1	GlsB/YeaQ/YmgE family stress response membrane protein	-
JGY90_RS08980 (JGY90_08940)	1853067..1853231	-	165	WP_158261830.1	hypothetical protein	-
JGY90_RS14255	1853846..1853968	-	123	WP_263855845.1	hypothetical protein	Toxin
-	1854065..1854227	+	163	-	-	Antitoxin
JGY90_RS08985	1854217..1854324	-	108	WP_081224963.1	putative holin-like toxin	-
JGY90_RS08990 (JGY90_08950)	1855130..1855321	-	192	WP_047172519.1	hypothetical protein	-
JGY90_RS09000 (JGY90_08960)	1855904..1856413	-	510	WP_042362896.1	metallophosphoesterase	-
JGY90_RS09005 (JGY90_08965)	1856413..1856994	-	582	WP_107538003.1	XTP/dITP diphosphatase	-
JGY90_RS09010 (JGY90_08970)	1857006..1857806	-	801	WP_029379028.1	glutamate racemase	-
JGY90_RS09015 (JGY90_08975)	1858014..1858826	-	813	WP_029379029.1	succinate dehydrogenase iron-sulfur subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 41 a.a.
• Molecular weight: 4399.05 Da
• Isoelectric Point: 4.4987

>T184839 WP_263855845.1 NZ_CP066726:c1853968-1853846 [Staphylococcus xylosus]
MTLVNQKLSNKGVNPIPVDESTLLTMAVPLITTWKDDSNN

Nucleotide

• Length: 123 bp

>T184839 NZ_CP087821:c637974-637747 [Moraxella bovis]
ATCTCTGAGCGAGCAGGTTCACGCATGGCTGTGGCGCTAAACGGGCAAGTCATGGTTTTTCATCGCCCACACCCAAGCCC
AAATACTGACAAAAGTGCGGTTATGAGCATTAGAAAATGGCTTGATGGCATGGGTATCACACCATTAGATGACGACAGCC
AAACAGACGAATACGCAGACAAACAAACCGACGAACAGGAGCAGACTCATGAACACAATGACAATTAA

Antitoxin

Nucleotide

• Length: 163 bp

>AT184839 NZ_CP066726:1854065-1854227 [Staphylococcus xylosus]
TTGATAATATTTTTATGTTGTGTTAATTTATAGATAGAAAAAGGGCAATACACCATAAGCGTATCGCCCTAATGAGCCCG
TTAAAAAGACGGTGGCTAGTTACTAATAATTATCAAAAAATAATCATCGAAACCGGCCAAAGTTAGCGATGGTTATTTTT
TAT

Structures

Antitoxin