Detailed information of TA system TA184828

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 1831550..1831779
• Replicon: chromosome
• Accession: NZ_CP066721
• Organism: Staphylococcus xylosus strain 2.1523

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: JGY88_RS08755
• Protein ID: WP_081224963.1
• Coordinates: 1831672..1831779 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF1
Locus tag	-
Coordinates	1831550..1831680 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JGY88_RS08720 (1827756)	1827756..1828004	-	249	WP_029379025.1	GlsB/YeaQ/YmgE family stress response membrane protein	-
JGY88_RS08725 (1829058)	1829058..1829222	-	165	WP_157821590.1	hypothetical protein	-
JGY88_RS08730 (1829838)	1829838..1830005	-	168	WP_225486442.1	hypothetical protein	-
JGY88_RS08735 (1830206)	1830206..1830313	-	108	WP_107546387.1	putative holin-like toxin	-
JGY88_RS08740 (1830584)	1830584..1830766	-	183	WP_225486443.1	hypothetical protein	-
JGY88_RS08745 (1830937)	1830937..1831044	-	108	WP_107538463.1	putative holin-like toxin	-
JGY88_RS08750 (1831321)	1831321..1831485	-	165	WP_225486444.1	hypothetical protein	-
- (1831550)	1831550..1831680	+	131	NuclAT_0	-	Antitoxin
- (1831550)	1831550..1831680	+	131	NuclAT_0	-	Antitoxin
- (1831550)	1831550..1831680	+	131	NuclAT_0	-	Antitoxin
- (1831550)	1831550..1831680	+	131	NuclAT_0	-	Antitoxin
JGY88_RS08755 (1831672)	1831672..1831779	-	108	WP_081224963.1	putative holin-like toxin	Toxin
JGY88_RS08760 (1831970)	1831970..1832716	-	747	WP_225486445.1	SGNH/GDSL hydrolase family protein	-
JGY88_RS08765 (1832850)	1832850..1832963	-	114	WP_225486941.1	YolD-like family protein	-
JGY88_RS08770 (1833053)	1833053..1833496	+	444	Protein_1698	hypothetical protein	-
JGY88_RS08780 (1834068)	1834068..1834577	-	510	WP_225486446.1	metallophosphoesterase	-
JGY88_RS08785 (1834577)	1834577..1835158	-	582	WP_047172560.1	XTP/dITP diphosphatase	-
JGY88_RS08790 (1835170)	1835170..1835970	-	801	WP_029379028.1	glutamate racemase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3760.71 Da
• Isoelectric Point: 10.4997

>T184828 WP_081224963.1 NZ_CP066721:c1831779-1831672 [Staphylococcus xylosus]
VVSIVEALHLMLGFGTFIVTLLGLVIAIVKLSHKK

Nucleotide

• Length: 108 bp

>T184828 NZ_CP087817:1718285-1718563 [Moraxella bovis]
ATGATTTTTGAATGGGACGACAACAAAAATCGGACAAACAAGCAAAAGCACGGTGTCAGCTTTGAGAGTGCAAGCCGTAT
TTTTCTTGACCCATTTTTGATTGTTACAGAAGACACAAGTTCTGATGAAGTGCGGTGGCTTGGTGTGGGTAGTGTAGATG
GCGTGGTGATTTTACTCGTTGTACACACCCATACTGATACAGACGGTACAGAAATCATTCGCATTATCTCAGCACGCAAA
CTTAGCAGAGGAGAAATAGAACGCTATGGCTATTGTTAG

Antitoxin

Nucleotide

• Length: 131 bp

>AT184828 NZ_CP066721:1831550-1831680 [Staphylococcus xylosus]
ATAGATAGAAAAAGGGCAACACACATAAGTGTATCGCCCCAGTGAGCCCGTTAAAAAGACGGTGGCTAGTTACTAATAAT
TATCAAAAAATAATCATCGAAACCGGCCAAAGTTAGCGATGGTTATTTTTT

Structures

Antitoxin