Detailed information of TA system TA184822

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): holin-SprF1/-
• Location: 1826953..1827334
• Replicon: chromosome
• Accession: NZ_CP066719
• Organism: Staphylococcus xylosus strain TMW 2.1602

Toxin (Protein)

• Gene name: holin
• Uniprot ID: -
• Locus tag: JGY87_RS08715
• Protein ID: WP_155238586.1
• Coordinates: 1826953..1827120 (-)
• Length: 56 a.a.

Antitoxin (RNA)

Gene name	SprF1
Locus tag	-
Coordinates	1827174..1827334 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JGY87_RS08690	1822385..1822564	-	180	WP_253676000.1	DUF5776 domain-containing protein	-
JGY87_RS08695 (JGY87_08640)	1822561..1824270	-	1710	WP_225489225.1	glycosyltransferase	-
JGY87_RS08700 (JGY87_08645)	1824955..1825428	+	474	Protein_1684	transposase	-
JGY87_RS08705 (JGY87_08650)	1825522..1825770	-	249	WP_029379025.1	GlsB/YeaQ/YmgE family stress response membrane protein	-
JGY87_RS08715 (JGY87_08660)	1826953..1827120	-	168	WP_155238586.1	hypothetical protein	Toxin
-	1827174..1827334	+	161	-	-	Antitoxin
JGY87_RS08720 (JGY87_08665)	1828189..1828425	-	237	WP_225489226.1	hypothetical protein	-
JGY87_RS08730 (JGY87_08675)	1829007..1829516	-	510	WP_058625608.1	metallophosphoesterase	-
JGY87_RS08735 (JGY87_08680)	1829516..1830097	-	582	WP_029379027.1	XTP/dITP diphosphatase	-
JGY87_RS08740 (JGY87_08685)	1830109..1830909	-	801	WP_029379028.1	glutamate racemase	-
JGY87_RS08745 (JGY87_08690)	1831117..1831929	-	813	WP_029379029.1	succinate dehydrogenase iron-sulfur subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 56 a.a.
• Molecular weight: 6159.16 Da
• Isoelectric Point: 6.1184

>T184822 WP_155238586.1 NZ_CP066719:c1827120-1826953 [Staphylococcus xylosus]
MYVKVTVIARVLSLVLTLVNQRLSNKSVNPILVDESTLLTMAEPLNTTWKDDSNN

Nucleotide

• Length: 168 bp

>T184822 NZ_CP087814:2082921-2083181 [Moraxella bovis]
ATTGAGGCCTTATTTGTAGCATTAGGGGCGGACATCTCTGAGCGAGCAGGTTCACGCATGGCTGTGGCGCTAAACGGGCA
AGTCATGGTTTTTCATCGCCCACACCCAAGCCCAAATACTGACAAAAGTGCGGTTATGAGCATTAGAAAATGGCTTGATG
GCATGGGTATCACACCATTAGATGACGACAGCCAAACAGACGAATACGCAGACAAACAAACCGACGAACAGGAGCAGACT
CATGAACACAATGACAATTAA

Antitoxin

Nucleotide

• Length: 161 bp

>AT184822 NZ_CP066719:1827174-1827334 [Staphylococcus xylosus]
TTGATAATATATTTATGTTGTGTTAATTTATAGATAGAAAAAGGGCAACACACCATAAATGTATCGCCCTAATGAGCCCG
TTAAAAAGACGGTGACCATTCTTTAATGATTATCTTTAATAACCATCGAACCGGTCAAAGTTAGCGATGGTTATTTTTTA
T

Structures

Antitoxin