Detailed information of TA system TA184805

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): TMCS/-
• Location: 1687271..1687851
• Replicon: chromosome
• Accession: NZ_CP066713
• Organism: Staphylococcus pseudintermedius strain DSP026

Toxin (Protein)

• Gene name: MW1434
• Uniprot ID: -
• Locus tag: JGZ50_RS08105
• Protein ID: WP_099999935.1
• Coordinates: 1687606..1687851 (-)
• Length: 82 a.a.

Antitoxin (RNA)

Gene name	MW1433
Locus tag	-
Coordinates	1687271..1687635 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JGZ50_RS08045	1682854..1683528	-	675	WP_199274693.1	hypothetical protein	-
JGZ50_RS08050	1683712..1684149	-	438	WP_199274694.1	single-stranded DNA-binding protein	-
JGZ50_RS08055	1684142..1684786	-	645	WP_065354600.1	ERF family protein	-
JGZ50_RS08060	1684790..1685338	-	549	WP_100004522.1	host-nuclease inhibitor Gam family protein	-
JGZ50_RS08065	1685331..1685585	-	255	WP_100005313.1	hypothetical protein	-
JGZ50_RS08070	1685597..1685857	-	261	WP_099999945.1	DUF1108 family protein	-
JGZ50_RS08075	1685937..1686122	-	186	WP_142403192.1	hypothetical protein	-
JGZ50_RS08080	1686128..1686355	-	228	WP_140230332.1	DUF771 domain-containing protein	-
JGZ50_RS08085	1686424..1686633	+	210	WP_099999943.1	hypothetical protein	-
JGZ50_RS08090	1686626..1686766	-	141	WP_099999941.1	hypothetical protein	-
JGZ50_RS08095	1686831..1687100	+	270	WP_099999939.1	hypothetical protein	-
-	1687271..1687635	+	365	-	-	Antitoxin
JGZ50_RS08105	1687606..1687851	-	246	WP_099999935.1	DUF2829 domain-containing protein	Toxin
JGZ50_RS08110	1687863..1688612	-	750	WP_199274695.1	phage antirepressor KilAC domain-containing protein	-
JGZ50_RS08115	1688650..1689093	-	444	WP_065354605.1	hypothetical protein	-
JGZ50_RS08120	1689105..1689347	-	243	WP_103926988.1	DUF739 family protein	-
JGZ50_RS08125	1689510..1690214	+	705	WP_140228747.1	LexA family transcriptional regulator	-
JGZ50_RS08130	1690226..1690393	+	168	WP_019165842.1	hypothetical protein	-
JGZ50_RS08135	1690406..1690891	+	486	WP_199274696.1	hypothetical protein	-
JGZ50_RS08140	1690938..1691135	+	198	WP_020219732.1	hypothetical protein	-
JGZ50_RS08145	1691136..1691732	-	597	WP_065520558.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	1651490..1696661	45171

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Protein of unknown function DUF2829 (2-69)

Sequences

Toxin

Protein

• Length: 82 a.a.
• Molecular weight: 9525.83 Da
• Isoelectric Point: 4.7204

>T184805 WP_099999935.1 NZ_CP066713:c1687851-1687606 [Staphylococcus pseudintermedius]
MNIQEATKMATKNLVSMTRKEWEESHRTKILPTNDSFLQCIISNNDGTNIIRYWQPSADDLMANDWEVINPIRDQELLKL
F

Nucleotide

• Length: 246 bp

>T184805 NZ_CP087811:c677691-677431 [Moraxella bovis]
ATTGAGGCCTTATTTGTAGCATTAGGGGCGGACATCTCTGAGCGAGCAGGTTCACGCATGGCTGTGGCGCTAAACGGGCA
AGTCATGGTTTTTCATCGCCCACACCCAAGCCCAAATACTGACAAAAGTGCGGTTATGAGCATTAGAAAATGGCTTGATG
GCATGGGTATCACACCATTAGATGACGACAGCCAAACAGACGAATACGCAGACAAACAAACCGACGAACAGGAGCAGACT
CATGAACACAATGACAATTAA

Antitoxin

Nucleotide

• Length: 365 bp

>AT184805 NZ_CP066713:1687271-1687635 [Staphylococcus pseudintermedius]
ATGACTTTAATATCTGATGAATTTGAAACACTTACTAAAGACCAACAATATATCTTGTCTGTACTCTACAAAGATTATTT
AGAATGTGTGAAATCTGGTTCTGTTAAATTGACTTGTAACAATTTCGATAGTGCTCAAGATATACATTTAAAATATTTTC
AGAAGTTACACTTCTGAAGATGTTGAAAATGATTTGAAAAAGCTTAAAAAGTATGAGTTTCTGAATGGTATTTTTGCTGA
TAACACAATTTATCAAGTGGTCATTTCTGACAAGACTATTGTGTACTTTGAAAATCAGTTTAAAAATAATTTAAAAAGTA
TAATTGATAGCATTTCTAAAATAGCTTCAGTAATTCCTGGTCTCT

Structures

Antitoxin