Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | yefM-yoeB (relBE)/Txe-RelB |
Location | 180430..180953 | Replicon | chromosome |
Accession | NZ_CP066712 | ||
Organism | Staphylococcus pseudintermedius strain DSP027 |
Toxin (Protein)
Gene name | yoeB | Uniprot ID | - |
Locus tag | JGZ40_RS00805 | Protein ID | WP_233276563.1 |
Coordinates | 180687..180953 (+) | Length | 89 a.a. |
Antitoxin (Protein)
Gene name | yefM | Uniprot ID | - |
Locus tag | JGZ40_RS00800 | Protein ID | WP_233276562.1 |
Coordinates | 180430..180687 (+) | Length | 86 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
JGZ40_RS00775 (JGZ40_00770) | 175767..175949 | - | 183 | WP_096536006.1 | hypothetical protein | - |
JGZ40_RS00780 (JGZ40_00775) | 176476..177282 | + | 807 | WP_233276559.1 | arylamine N-acetyltransferase | - |
JGZ40_RS00785 (JGZ40_00780) | 177576..178070 | - | 495 | WP_015729749.1 | isoprenylcysteine carboxylmethyltransferase family protein | - |
JGZ40_RS00790 | 178330..178692 | + | 363 | WP_233276560.1 | MSCRAMM family adhesin SdrC | - |
JGZ40_RS00795 | 179202..180236 | + | 1035 | WP_233276561.1 | triacylglycerol lipase | - |
JGZ40_RS00800 (JGZ40_00790) | 180430..180687 | + | 258 | WP_233276562.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
JGZ40_RS00805 (JGZ40_00795) | 180687..180953 | + | 267 | WP_233276563.1 | Txe/YoeB family addiction module toxin | Toxin |
JGZ40_RS00810 (JGZ40_00800) | 181315..181416 | - | 102 | WP_101431314.1 | SE2200 family small protein | - |
JGZ40_RS00815 (JGZ40_00805) | 181430..182923 | - | 1494 | WP_014612817.1 | L-lactate dehydrogenase (quinone) | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 89 a.a. Molecular weight: 10527.05 Da Isoelectric Point: 10.1602
>T184799 WP_233276563.1 NZ_CP066712:180687-180953 [Staphylococcus pseudintermedius]
MGNYSVLIKNSAKNDLKKIKKSLLKEQFSKIIEVLKINPYEASQSFEKLQPKHSARYSRRLNHQHRVVYTVDDEKREAYI
FSAWSYYE
MGNYSVLIKNSAKNDLKKIKKSLLKEQFSKIIEVLKINPYEASQSFEKLQPKHSARYSRRLNHQHRVVYTVDDEKREAYI
FSAWSYYE
Download Length: 267 bp
>T184799 NZ_CP087806:c1853745-1853410 [Moraxella bovis]
ATGTTGCATTTTGCTGAAACATCATTATTCACTAAACAAATCATAGACTTAATGGATGATGACGAGTACAGACTATTACA
AACAAACTTGATGAAAAACCCACATCAAGGCGACATTGTTCGTGGTACTGGCGGAGTACGCAAAACAAGATGGTCAATTG
ATGGCAAGGGCAAAAGTGGTGGCAGTCGCATCATTTACTTTTTTGTTGATGGTGCTGGCATTTTCTTTATGCTCTTGGCT
TATCCTAAATCAAAACAAACAACGCTATCGGCGGATGAGAAAAAAGAAATGCTCAAACTAACCACCGCAATTAAGGAGAT
TTACCGTGCAAAATGA
ATGTTGCATTTTGCTGAAACATCATTATTCACTAAACAAATCATAGACTTAATGGATGATGACGAGTACAGACTATTACA
AACAAACTTGATGAAAAACCCACATCAAGGCGACATTGTTCGTGGTACTGGCGGAGTACGCAAAACAAGATGGTCAATTG
ATGGCAAGGGCAAAAGTGGTGGCAGTCGCATCATTTACTTTTTTGTTGATGGTGCTGGCATTTTCTTTATGCTCTTGGCT
TATCCTAAATCAAAACAAACAACGCTATCGGCGGATGAGAAAAAAGAAATGCTCAAACTAACCACCGCAATTAAGGAGAT
TTACCGTGCAAAATGA
Antitoxin
Download Length: 86 a.a. Molecular weight: 9852.85 Da Isoelectric Point: 4.1100
>AT184799 WP_233276562.1 NZ_CP066712:180430-180687 [Staphylococcus pseudintermedius]
MIIKTPTNARKEFYELLKQVNDNHEPIVISGSKSENNAVIVSQEDWDSIQETLFLEYTGTMDKVRAREKDDSGYTNIDDI
DWDNL
MIIKTPTNARKEFYELLKQVNDNHEPIVISGSKSENNAVIVSQEDWDSIQETLFLEYTGTMDKVRAREKDDSGYTNIDDI
DWDNL
Download Length: 258 bp
>AT184799 NZ_CP087806:c1853420-1853139 [Moraxella bovis]
GTGCAAAATGAGTTTTACGATGATTTAAAAGCCTCATTGACTGAGGCTCTGGCAATCGCTAAGGGCGAAATTTCCCCAAG
TCGTACATTCACTTATGAACGCCCAAACATCAAAGATATTCGGGCAAAAACAGGGCTATCACAAACCCAGTTCGCCCAGA
AGCTACACATAAGCCCTAAAACGCTTAAAAACTGGGAACAGGGCATTAGAACGCCAACAGGTCCAGCCATTACCCTAATT
AGATTACTTGACAAAAACCCTGATTTAATTAGCATGGCATAA
GTGCAAAATGAGTTTTACGATGATTTAAAAGCCTCATTGACTGAGGCTCTGGCAATCGCTAAGGGCGAAATTTCCCCAAG
TCGTACATTCACTTATGAACGCCCAAACATCAAAGATATTCGGGCAAAAACAGGGCTATCACAAACCCAGTTCGCCCAGA
AGCTACACATAAGCCCTAAAACGCTTAAAAACTGGGAACAGGGCATTAGAACGCCAACAGGTCCAGCCATTACCCTAATT
AGATTACTTGACAAAAACCCTGATTTAATTAGCATGGCATAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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