Detailed information of TA system TA184799

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yefM-yoeB (relBE)/Txe-RelB
• Location: 180430..180953
• Replicon: chromosome
• Accession: NZ_CP066712
• Organism: Staphylococcus pseudintermedius strain DSP027

Toxin (Protein)

• Gene name: yoeB
• Uniprot ID: -
• Locus tag: JGZ40_RS00805
• Protein ID: WP_233276563.1
• Coordinates: 180687..180953 (+)
• Length: 89 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: JGZ40_RS00800
• Protein ID: WP_233276562.1
• Coordinates: 180430..180687 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JGZ40_RS00775 (JGZ40_00770)	175767..175949	-	183	WP_096536006.1	hypothetical protein	-
JGZ40_RS00780 (JGZ40_00775)	176476..177282	+	807	WP_233276559.1	arylamine N-acetyltransferase	-
JGZ40_RS00785 (JGZ40_00780)	177576..178070	-	495	WP_015729749.1	isoprenylcysteine carboxylmethyltransferase family protein	-
JGZ40_RS00790	178330..178692	+	363	WP_233276560.1	MSCRAMM family adhesin SdrC	-
JGZ40_RS00795	179202..180236	+	1035	WP_233276561.1	triacylglycerol lipase	-
JGZ40_RS00800 (JGZ40_00790)	180430..180687	+	258	WP_233276562.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
JGZ40_RS00805 (JGZ40_00795)	180687..180953	+	267	WP_233276563.1	Txe/YoeB family addiction module toxin	Toxin
JGZ40_RS00810 (JGZ40_00800)	181315..181416	-	102	WP_101431314.1	SE2200 family small protein	-
JGZ40_RS00815 (JGZ40_00805)	181430..182923	-	1494	WP_014612817.1	L-lactate dehydrogenase (quinone)	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (25-75)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-68)

Sequences

Toxin

Protein

• Length: 89 a.a.
• Molecular weight: 10527.05 Da
• Isoelectric Point: 10.1602

>T184799 WP_233276563.1 NZ_CP066712:180687-180953 [Staphylococcus pseudintermedius]
MGNYSVLIKNSAKNDLKKIKKSLLKEQFSKIIEVLKINPYEASQSFEKLQPKHSARYSRRLNHQHRVVYTVDDEKREAYI
FSAWSYYE

Nucleotide

• Length: 267 bp

>T184799 NZ_CP087806:c1853745-1853410 [Moraxella bovis]
ATGTTGCATTTTGCTGAAACATCATTATTCACTAAACAAATCATAGACTTAATGGATGATGACGAGTACAGACTATTACA
AACAAACTTGATGAAAAACCCACATCAAGGCGACATTGTTCGTGGTACTGGCGGAGTACGCAAAACAAGATGGTCAATTG
ATGGCAAGGGCAAAAGTGGTGGCAGTCGCATCATTTACTTTTTTGTTGATGGTGCTGGCATTTTCTTTATGCTCTTGGCT
TATCCTAAATCAAAACAAACAACGCTATCGGCGGATGAGAAAAAAGAAATGCTCAAACTAACCACCGCAATTAAGGAGAT
TTACCGTGCAAAATGA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9852.85 Da
• Isoelectric Point: 4.1100

>AT184799 WP_233276562.1 NZ_CP066712:180430-180687 [Staphylococcus pseudintermedius]
MIIKTPTNARKEFYELLKQVNDNHEPIVISGSKSENNAVIVSQEDWDSIQETLFLEYTGTMDKVRAREKDDSGYTNIDDI
DWDNL

Nucleotide

• Length: 258 bp

>AT184799 NZ_CP087806:c1853420-1853139 [Moraxella bovis]
GTGCAAAATGAGTTTTACGATGATTTAAAAGCCTCATTGACTGAGGCTCTGGCAATCGCTAAGGGCGAAATTTCCCCAAG
TCGTACATTCACTTATGAACGCCCAAACATCAAAGATATTCGGGCAAAAACAGGGCTATCACAAACCCAGTTCGCCCAGA
AGCTACACATAAGCCCTAAAACGCTTAAAAACTGGGAACAGGGCATTAGAACGCCAACAGGTCCAGCCATTACCCTAATT
AGATTACTTGACAAAAACCCTGATTTAATTAGCATGGCATAA