Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | yefM-yoeB (relBE)/YoeB-YefM |
Location | 613184..613686 | Replicon | chromosome |
Accession | NZ_CP066552 | ||
Organism | Pectobacterium carotovorum strain 2A |
Toxin (Protein)
Gene name | yoeB | Uniprot ID | A0A7T5UAW5 |
Locus tag | JFY74_RS02765 | Protein ID | WP_039493889.1 |
Coordinates | 613184..613438 (-) | Length | 85 a.a. |
Antitoxin (Protein)
Gene name | yefM | Uniprot ID | A0A7W2E625 |
Locus tag | JFY74_RS02770 | Protein ID | WP_039324900.1 |
Coordinates | 613435..613686 (-) | Length | 84 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
JFY74_RS02745 | 608337..609599 | - | 1263 | WP_180744549.1 | L-rhamnose isomerase | - |
JFY74_RS02750 | 609596..611086 | - | 1491 | WP_198998065.1 | rhamnulokinase | - |
JFY74_RS02755 | 611423..612262 | + | 840 | WP_039493893.1 | HTH-type transcriptional activator RhaS | - |
JFY74_RS02760 | 612287..613141 | + | 855 | WP_039507370.1 | helix-turn-helix domain-containing protein | - |
JFY74_RS02765 | 613184..613438 | - | 255 | WP_039493889.1 | Txe/YoeB family addiction module toxin | Toxin |
JFY74_RS02770 | 613435..613686 | - | 252 | WP_039324900.1 | YoeB-YefM toxin-antitoxin system antitoxin YefM | Antitoxin |
JFY74_RS02775 | 613762..615468 | - | 1707 | WP_198998066.1 | ABC transporter ATP-binding protein | - |
JFY74_RS02780 | 615465..616331 | - | 867 | WP_198998067.1 | ABC transporter permease | - |
JFY74_RS02785 | 616324..617283 | - | 960 | WP_039470517.1 | ABC transporter permease | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 85 a.a. Molecular weight: 10228.81 Da Isoelectric Point: 8.8560
>T184652 WP_039493889.1 NZ_CP066552:c613438-613184 [Pectobacterium carotovorum]
VKLIWSEEAWEDYLYWQDIDKRMVKKINELIKETRRTPFEGKGKPEPLKHNLAGFWSRRITEEHRLVYAITNDAMMIAAC
RYHY
VKLIWSEEAWEDYLYWQDIDKRMVKKINELIKETRRTPFEGKGKPEPLKHNLAGFWSRRITEEHRLVYAITNDAMMIAAC
RYHY
Download Length: 255 bp
>T184652 NZ_CP087763:982871-983176 [Lactobacillus gasseri]
ATGGCTCAAATTAACTACACTCCTCAATTTAAGCGAGATTATAAGAAGCTTAAAAGAAAACATTATGATTTGAATAAATT
AAAAAATGTCATTCAATTACTTATTGACGAAAAATTTAAAATTCTTGTTGATAAATATGATGACCATCAACTAAAAGGTT
CTTTAAGGTCACTACGTGCATTACATGTTGAGCATAATAAAGCTGGTAATTGGATTTTAGTTTATAAAATTCATAGCGGC
AATTTAGAACTGTTAACCATCGACTTGGTTTCTACTGGTTCCCACGATCATACTTATAGAACATAA
ATGGCTCAAATTAACTACACTCCTCAATTTAAGCGAGATTATAAGAAGCTTAAAAGAAAACATTATGATTTGAATAAATT
AAAAAATGTCATTCAATTACTTATTGACGAAAAATTTAAAATTCTTGTTGATAAATATGATGACCATCAACTAAAAGGTT
CTTTAAGGTCACTACGTGCATTACATGTTGAGCATAATAAAGCTGGTAATTGGATTTTAGTTTATAAAATTCATAGCGGC
AATTTAGAACTGTTAACCATCGACTTGGTTTCTACTGGTTCCCACGATCATACTTATAGAACATAA
Antitoxin
Download Length: 84 a.a. Molecular weight: 9367.64 Da Isoelectric Point: 4.6119
>AT184652 WP_039324900.1 NZ_CP066552:c613686-613435 [Pectobacterium carotovorum]
MRTISYSEARQNLSATMMKTVEDRAPILITRQNGEACVLMSLEEYNSLEETAYLLRSPANAKRLMNSIESLKAGNGEERD
IIE
MRTISYSEARQNLSATMMKTVEDRAPILITRQNGEACVLMSLEEYNSLEETAYLLRSPANAKRLMNSIESLKAGNGEERD
IIE
Download Length: 252 bp
>AT184652 NZ_CP087763:982596-982871 [Lactobacillus gasseri]
ATGACAACTACCGTAAGTTTAAGATTACCAGAAGATTTAAAGAAACAAGCAACAGATGTATTCAACGAATACGGTCTCGA
TTGGTCATCTGCAATGCGAATGATCTTAACTCAAGTCGTAAGTGAAAATGCAATTCCTGTTAATTTACATAGATATTCTG
AAATTTCTCCTTCGATGAAATCAAATATTGATAGATCACTTCAAGAATACAAAGCAGGAAATTACAAAACCACAAACTCA
GTAAAAGAGCTATTTGAGGAGTTAGATAAAGACTAA
ATGACAACTACCGTAAGTTTAAGATTACCAGAAGATTTAAAGAAACAAGCAACAGATGTATTCAACGAATACGGTCTCGA
TTGGTCATCTGCAATGCGAATGATCTTAACTCAAGTCGTAAGTGAAAATGCAATTCCTGTTAATTTACATAGATATTCTG
AAATTTCTCCTTCGATGAAATCAAATATTGATAGATCACTTCAAGAATACAAAGCAGGAAATTACAAAACCACAAACTCA
GTAAAAGAGCTATTTGAGGAGTTAGATAAAGACTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7T5UAW5 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7W2E625 |