Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 5216509..5217163 Replicon chromosome
Accession NZ_CP066546
Organism Pseudomonas chlororaphis subsp. aureofaciens strain SPS-41

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag JE032_RS23275 Protein ID WP_110175823.1
Coordinates 5216509..5216859 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag JE032_RS23280 Protein ID WP_009049793.1
Coordinates 5216849..5217163 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JE032_RS23265 5213259..5214791 + 1533 WP_009049790.1 NADH-quinone oxidoreductase subunit M -
JE032_RS23270 5214799..5216262 + 1464 WP_009049791.1 NADH-quinone oxidoreductase subunit NuoN -
JE032_RS23275 5216509..5216859 + 351 WP_110175823.1 toxin Toxin
JE032_RS23280 5216849..5217163 + 315 WP_009049793.1 transcriptional regulator Antitoxin
JE032_RS23285 5217330..5219072 - 1743 WP_023964376.1 ABC transporter substrate-binding protein -
JE032_RS23290 5219236..5219508 - 273 WP_009049795.1 DUF2160 domain-containing protein -
JE032_RS23295 5219519..5220319 - 801 WP_007929618.1 carbohydrate ABC transporter permease -
JE032_RS23300 5220331..5221197 - 867 WP_016701903.1 sugar ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(41-100)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13929.93 Da        Isoelectric Point: 9.7779

>T184646 WP_110175823.1 NZ_CP066546:5216509-5216859 [Pseudomonas chlororaphis subsp. aureofaciens]
MGALFIELPPFQRHRQDYLDDELFRNLQLELLKAPEAGDLIERTDGLRKIRFVDERRHKGKRGGIRVIYYWWSGGAQFWL
FTLYAKNEQNDLTPHQKKLLKQLLNREVEARTHHET

Download         Length: 351 bp

>T184646 NZ_CP087718:3811-4131 [Acinetobacter pittii]
ATGTTATTTATTGAAACCAGCATCTTTACCAAGCAAATTAAAGACCTTGTATCTGATGAGGAATATCGTCAACTTCAGCA
AGATCTTTTGGTACAGCCTGATAGAGGTGACCTAATCAAGAATGGCGGTGGTATTCGCAAAGTACGTTGTGCTCAAGGTA
ACAAAGGGAAAAGTGGTGGGATACGGGTGATTTATTATTGGGTCACCGAGGATGATCAGATCTTTTTCTTAGTGGCTTAT
CCAAAATCAGTAAAAGATAATTTAACAGATAAGGAAACCGCCATTCTGCACCAACTCGTGAAGGAGCAATTTCATGGATA
A

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11917.85 Da        Isoelectric Point: 10.6052

>AT184646 WP_009049793.1 NZ_CP066546:5216849-5217163 [Pseudomonas chlororaphis subsp. aureofaciens]
MKRDIFSELVEGFDALAKERQGKLTLRTYKVKLNALLPITAEEVLAVREQLNLSRSVFAMYLRTNTRTLENWEQGRAKPN
AQATTLIRLVQRFPDTVERLAALA

Download         Length: 315 bp

>AT184646 NZ_CP087718:4124-4396 [Acinetobacter pittii]
ATGGATAACAACTTATTTGATGACTTGGTTGCTTCAATCAAAGAAGCTGGAGCTATCAAACGTAAAGAAGTTAAAGCAAG
CCGAGTTACAGAACTCGAATTGCCTGATATTAAAGAAGTACGTGAAAAAACTGGCTTGAGCCAAAATGAATTTGCTGCAC
GTCTACATATTAGCCCCCGTACCCTGCAAAATTGGGAACAGGGACGACGCTATCCAACTGGACCAGCAGCTACATTGATT
CGAATTTTAGATGCTCACCCAAGCCTTATTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References