Detailed information of TA system TA184486

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1881589..1881769
• Replicon: chromosome
• Accession: NZ_CP066492
• Organism: Staphylococcus aureus strain nan_175_F371_ch

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: JF380_RS09145
• Protein ID: WP_001801861.1
• Coordinates: 1881589..1881684 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1881712..1881769 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JF380_RS09110	1876630..1877256	+	627	WP_000669019.1	hypothetical protein	-
JF380_RS09115	1877297..1877638	+	342	WP_000627548.1	DUF3969 family protein	-
JF380_RS09120	1877739..1878311	+	573	Protein_1795	hypothetical protein	-
JF380_RS09125	1878509..1879066	-	558	WP_000864138.1	ImmA/IrrE family metallo-endopeptidase	-
JF380_RS09130	1879437..1879613	-	177	WP_000375476.1	hypothetical protein	-
JF380_RS09135	1879624..1880007	-	384	WP_000070811.1	hypothetical protein	-
JF380_RS09140	1880692..1881138	-	447	WP_000747802.1	DUF1433 domain-containing protein	-
JF380_RS09145	1881589..1881684	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1881712..1881769	-	58	-	-	Antitoxin
JF380_RS09150	1881807..1881908	+	102	WP_001791232.1	hypothetical protein	-
JF380_RS09155	1881886..1882068	-	183	Protein_1802	transposase	-
JF380_RS09160	1882256..1882642	-	387	WP_198914271.1	DUF1433 domain-containing protein	-
JF380_RS09165	1882631..1882979	-	349	Protein_1804	DUF1433 domain-containing protein	-
JF380_RS09170	1883204..1883644	-	441	Protein_1805	DUF1433 domain-containing protein	-
JF380_RS09175	1884290..1885408	-	1119	WP_000072558.1	restriction endonuclease subunit S	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	lukD / hlgA	1874070..1947840	73770

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T184486 WP_001801861.1 NZ_CP066492:1881589-1881684 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T184486 NZ_CP087669:c4642862-4642329 [Klebsiella pneumoniae]
ATGGAGCAGCAACTGACGATTGAGATGATTGCCGATGCGTTCAGCTACGATATCACTGGATTTGATTGCGGCGAGGAAGC
GCTGAATACGTTTTTAAAAGAGCACCTCAAGCGGCAGCACGATGGACAAATCTTAAGGGGTTATGCGCTGGTCTCCGGGG
ATACCGTTCCCAGGTTGCTGGGTTATTACACCTTATCGGGGAGTTGTTTCGAGCGAGGCATGTTGCCGTCTAAAACTCAG
CAAAAGAAAATCCCGTATCAAAATGCGCCAAGCGTAACCCTCGGGCGGCTGGCCATTGATAAATCTGTTCAGGGGCAGGG
CTGGGGAGAGATGTTGGTTGCCCATGCGATGCGAGTGGTGTGGGGAGCGTCTAAAGCCGTTGGCATCTACGGATTGTTTG
TTGAAGCCCTTAATGAGAAGGCTAAAGCATTCTATCTTCGTCTGGGGTTTATACAGCTCGTGGATAAAAATAGTAACTTA
CTGTTTTATCCGACCAAATCGATTGAACAGCTCTTTACTGACGATGAGTCATAA

Antitoxin

Nucleotide

• Length: 58 bp

>AT184486 NZ_CP066492:c1881769-1881712 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin