184257

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HTH(antitoxin)
Location 3717120..3717760 Replicon chromosome
Accession NZ_CP066265
Organism Pseudomonas syringae strain PA-2-9E

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag I9H07_RS16505 Protein ID WP_024675597.1
Coordinates 3717120..3717434 (+) Length 105 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag I9H07_RS16510 Protein ID WP_032606649.1
Coordinates 3717434..3717760 (+) Length 109 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I9H07_RS16490 (I9H07_16380) 3712298..3713632 + 1335 WP_058824096.1 AcvB/VirJ family lysyl-phosphatidylglycerol hydrolase -
I9H07_RS16495 (I9H07_16385) 3713729..3715624 - 1896 WP_024675595.1 potassium transporter Kup -
I9H07_RS16500 (I9H07_16390) 3715950..3717041 + 1092 WP_024675596.1 catalase family protein -
I9H07_RS16505 (I9H07_16395) 3717120..3717434 + 315 WP_024675597.1 hypothetical protein Toxin
I9H07_RS16510 (I9H07_16400) 3717434..3717760 + 327 WP_032606649.1 helix-turn-helix domain-containing protein Antitoxin
I9H07_RS16515 (I9H07_16405) 3718319..3719704 + 1386 WP_236425566.1 hypothetical protein -
I9H07_RS16520 (I9H07_16410) 3720421..3721215 - 795 WP_236425567.1 DNA adenine methylase -
I9H07_RS16525 (I9H07_16415) 3721809..3722057 + 249 WP_236425568.1 hypothetical protein -
I9H07_RS16530 3722057..3722353 + 297 WP_236425569.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(36-88)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11928.71 Da        Isoelectric Point: 9.9587

>T184257 WP_024675597.1 NZ_CP066265:3717120-3717434 [Pseudomonas syringae]
MIFIETPVFTSDLRDHLDDEAYRALQIYLAEHPESGALIEDTGGLRKIRWAAHGKGKSGGVRVIYYHVSARFQIRMILIY
RKGIQDSLTDKQKAQLRAINNGWK

Download         Length: 315 bp

>T184257 NZ_CP087580:836901-837311 [Klebsiella quasipneumoniae]
GTGGTCCTGTGGCAATCTGATCTCCGTATCTCCTGGCGCGCGCAGTGGTTTTCCCTGCTGCTCCACGGCGTTGTGGCGGC
GCTGGTGCTGCTGGTTCCCTGGCCGTTAAGCTACACCCCGATCTGGCTGCTGCTGCTGTCGCTGGTGGTCTTTGACTGTG
TGCGCAGCCAGCGACGGATCCATGCCCGTCGCGGGGAGATAAAACTGCTCACCGATTCCCGGCTGCGCTGGCAAAACGCC
GACTGGGAGATCCTCGGGACGCCGTGGGTCATCAACAGCGGAATGCTGCTGCGTTTGCGCCATGTCGATACCCGACGCGG
TCAGCATCTGTGGCTGGCGGCGGACAGCATGGATGCCGGAGAGTGGCGGGACCTGCGCCGGCTGGTGCTGCAAAAACCGG
CGCAGGAGTAA

Antitoxin


Download         Length: 109 a.a.        Molecular weight: 12364.98 Da        Isoelectric Point: 7.3231

>AT184257 WP_032606649.1 NZ_CP066265:3717434-3717760 [Pseudomonas syringae]
MEKNLFDRLVESMTEMDEIDRGERQPSREFHIDAVQVKKIRQATGLSQATFAKRIDVAVGTLRNWEQGRREPEGPARALL
RAIHNDPEHVLAALSFNRGEIADTKRLN

Download         Length: 327 bp

>AT184257 NZ_CP087580:836654-836920 [Klebsiella quasipneumoniae]
ATGGACATTAACAATAAAGCACGTATCCACTGGGCATGCCGCCGCGGGATGCGCGAACTCGACATCTCCATCATGCCGTT
CTTTGAGTATGAGTACGATACCCTCAGCGACGCTGACAAACAGCTGTTCATTCGCCTGCTGGAAAATGACGATCCGGATC
TATTCAACTGGCTGATGAACCATGGCAAACCGGCCGATGCGGAGCTGCAGCGGATGGTAACCTTAATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References