Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 47798..48456 Replicon plasmid pG20AB007-1
Accession NZ_CP066238
Organism Acinetobacter baumannii strain G20AB007

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag JCR16_RS19545 Protein ID WP_000312250.1
Coordinates 48097..48456 (-) Length 120 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag JCR16_RS19540 Protein ID WP_001096429.1
Coordinates 47798..48097 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JCR16_RS19495 42831..43088 + 258 WP_000834292.1 hypothetical protein -
JCR16_RS19500 43093..43665 + 573 WP_000429351.1 hypothetical protein -
JCR16_RS19505 43641..43820 + 180 WP_002081921.1 hypothetical protein -
JCR16_RS19510 43837..44466 + 630 WP_002081923.1 hypothetical protein -
JCR16_RS19515 44506..45015 + 510 WP_001043199.1 hypothetical protein -
JCR16_RS19520 45096..45650 + 555 WP_000790085.1 hypothetical protein -
JCR16_RS19525 45700..46236 + 537 WP_000731981.1 hypothetical protein -
JCR16_RS19530 46859..47341 + 483 WP_001052677.1 hypothetical protein -
JCR16_RS19535 47434..47697 - 264 WP_000110863.1 hypothetical protein -
JCR16_RS19540 47798..48097 - 300 WP_001096429.1 helix-turn-helix transcriptional regulator Antitoxin
JCR16_RS19545 48097..48456 - 360 WP_000312250.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JCR16_RS19550 48657..49223 + 567 WP_041171756.1 hypothetical protein -
JCR16_RS19555 49272..49454 + 183 WP_000373385.1 hypothetical protein -
JCR16_RS19560 49521..50219 + 699 WP_000873190.1 hypothetical protein -
JCR16_RS19565 50358..50741 + 384 WP_000654349.1 hypothetical protein -
JCR16_RS19570 50808..51566 + 759 WP_001053129.1 hypothetical protein -
JCR16_RS19575 52636..52950 + 315 WP_000708714.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..73361 73361


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(14-109)

Antitoxin

HigA2-like, helix-turn-helix domain

(12-88)


Sequences

Toxin        


Download         Length: 120 a.a.        Molecular weight: 13751.62 Da        Isoelectric Point: 4.8212

>T184194 WP_000312250.1 NZ_CP066238:c48456-48097 [Acinetobacter baumannii]
MAWDVETTELFDSWLAEQDENAQDKILASLLVLSELGPNLGRPHVDTIKESKYPNMKEIRVQVKGHPIRGFFAFDPERKA
IVLCAGDKKGLNEKAFYKEMIKIADEQYEQYLRDNYGDK

Download         Length: 360 bp

>T184194 NZ_CP087564:c2971319-2971212 [Escherichia coli]
ATGACGTTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 11012.93 Da        Isoelectric Point: 10.4856

>AT184194 WP_001096429.1 NZ_CP066238:c48097-47798 [Acinetobacter baumannii]
MAKLNDIISKRSPESQQRIKKMANQMLLDINLSNLREELKISQAEIAKNLGVSQAAISKREKLGKDLKISSLKEYVEAMG
GKVRLDVELPNGKHVAISI

Download         Length: 300 bp

>AT184194 NZ_CP087564:2971367-2971433 [Escherichia coli]
GGTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References