Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-HTH
Location 2124548..2125133 Replicon chromosome
Accession NZ_CP066121
Organism Acinetobacter bereziniae strain GD0320

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag I9190_RS09740 Protein ID WP_121774457.1
Coordinates 2124813..2125133 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID A0A8I1A8A3
Locus tag I9190_RS09735 Protein ID WP_058971122.1
Coordinates 2124548..2124820 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I9190_RS09720 2120252..2122453 - 2202 WP_100885315.1 glycerol-3-phosphate 1-O-acyltransferase PlsB -
I9190_RS09725 2122687..2123685 + 999 WP_042088689.1 cysteine synthase A -
I9190_RS09730 2123960..2124466 - 507 WP_121774458.1 ATP-binding protein -
I9190_RS09735 2124548..2124820 - 273 WP_058971122.1 helix-turn-helix domain-containing protein Antitoxin
I9190_RS09740 2124813..2125133 - 321 WP_121774457.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
I9190_RS09745 2125518..2126054 - 537 WP_042088690.1 lytic transglycosylase domain-containing protein -
I9190_RS09750 2126918..2129542 + 2625 WP_200232582.1 type VI secretion system tip protein VgrG -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(40-102)

Antitoxin

Cro/C1-type helix-turn-helix domain

(37-75)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12187.02 Da        Isoelectric Point: 7.1644

>T183978 WP_121774457.1 NZ_CP066121:c2125133-2124813 [Acinetobacter bereziniae]
MLFIETSIFTKQIKELVTDDEYRQLQQDLLVEPDKGDVIKNGGGIRKVRCAQGNKAKSGGIRVIYYWVSEDDHIFFLVAY
PKSMKDNLTDKETAILRQLVKEQLHG

Download         Length: 321 bp

>T183978 NZ_CP087287:c4659854-4659747 [Escherichia coli]
ATGACGCTCGCAGAACTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAATAAGCGGAAGTAA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10135.62 Da        Isoelectric Point: 9.9218

>AT183978 WP_058971122.1 NZ_CP066121:c2124820-2124548 [Acinetobacter bereziniae]
MDNTLFDDLVSSIKEAGAIKRKEIQASRVTELVLPNIKDVREKTGLSQNEFAARLHISPRTLQNWEQGRRYPTGPAATLI
RILDAHPTLI

Download         Length: 273 bp

>AT183978 NZ_CP087287:4659911-4659968 [Escherichia coli]
TCAAGATTAGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References