Detailed information of TA system TA183875

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): symE-timR/SymE(toxin)
• Location: 418215..418627
• Replicon: chromosome
• Accession: NZ_CP066085
• Organism: Escherichia fergusonii strain FDAARGOS_1032

Toxin (Protein)

• Gene name: symE
• Uniprot ID: -
• Locus tag: I6H89_RS02090
• Protein ID: WP_000132635.1
• Coordinates: 418286..418627 (+)
• Length: 114 a.a.

Antitoxin (RNA)

Gene name	timR
Locus tag	-
Coordinates	418215..418291 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
I6H89_RS02080	414964..416553	+	1590	WP_001063202.1	type I restriction-modification system methyltransferase	-
I6H89_RS02085	416550..418058	+	1509	WP_001272443.1	restriction endonuclease subunit S	-
-	418215..418291	-	77	NuclAT_15	-	Antitoxin
-	418215..418291	-	77	NuclAT_15	-	Antitoxin
-	418215..418291	-	77	NuclAT_15	-	Antitoxin
-	418215..418291	-	77	NuclAT_15	-	Antitoxin
-	418215..418291	-	77	NuclAT_16	-	Antitoxin
-	418215..418291	-	77	NuclAT_16	-	Antitoxin
-	418215..418291	-	77	NuclAT_16	-	Antitoxin
-	418215..418291	-	77	NuclAT_16	-	Antitoxin
I6H89_RS02090	418286..418627	+	342	WP_000132635.1	endoribonuclease SymE	Toxin
I6H89_RS02095	418789..420168	+	1380	WP_015953743.1	5-methylcytosine-specific restriction endonuclease subunit McrB	-
I6H89_RS02100	420168..421214	+	1047	WP_015953744.1	5-methylcytosine-specific restriction endonuclease system specificity protein McrC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin SymE-like (20-71)

Sequences

Toxin

Protein

• Length: 114 a.a.
• Molecular weight: 12310.12 Da
• Isoelectric Point: 7.8218

>T183875 WP_000132635.1 NZ_CP066085:418286-418627 [Escherichia fergusonii]
MTDTHSIAQPFEAEVSPANNRQLTVSYASRYPDYSRIPAITLKGQWLEVAGFATGTAVDVKVMEGCIVLTAQPPAAEESE
LMQSLRQVCKLSARKQKQVQDFIGVIAGKQKVA

Nucleotide

• Length: 342 bp

>T183875 NZ_CP087198:4111468-4111743 [Pseudomonas sp. B21-010]
ATGGAGTTGAAGTGGACCAGCAAGGCGCTTTCCGACATTGCTCGACTTTATGAATTTCTGGCGGCGGTGAATCAACCCGC
GGCCGCGCGAACAGTGCAACAACTCACGGCCGCGCCAACCTCTCTGCTGGCCAACCCGCGCATTGGTGAACGCCTGGAAG
AGTTCGAACCTCGAGACGTACGCAGAATCCAAGTGGGGCGCTACGAAATGCGCTATGGAATAGCCGGTTCCACCCTTTAC
CTGCTACGCCTGTGGCACACACGTGAGGATCGATGA

Antitoxin

Nucleotide

• Length: 77 bp

>AT183875 NZ_CP066085:c418291-418215 [Escherichia fergusonii]
AGTCATAACTGCTATTCTCCTGAAATAGTGATTGTGATGAGCGGTGCGGGTGTGTTGGCGCACATCCGCACCGCGCT

Structures

Antitoxin