Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 943439..943994 Replicon chromosome
Accession NZ_CP066076
Organism Paraburkholderia ginsengisoli strain FDAARGOS_1049

Toxin (Protein)


Gene name yoeB Uniprot ID A0A7T4N9K7
Locus tag I6I06_RS20910 Protein ID WP_042327933.1
Coordinates 943743..943994 (+) Length 84 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A7T4TBV9
Locus tag I6I06_RS20905 Protein ID WP_042327932.1
Coordinates 943439..943732 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6I06_RS20890 939218..940888 - 1671 WP_042327929.1 malonate decarboxylase subunit alpha -
I6I06_RS20895 940897..941670 - 774 WP_042327930.1 GntR family transcriptional regulator -
I6I06_RS20900 941863..943161 + 1299 WP_174447427.1 MFS transporter -
I6I06_RS20905 943439..943732 + 294 WP_042327932.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
I6I06_RS20910 943743..943994 + 252 WP_042327933.1 Txe/YoeB family addiction module toxin Toxin
I6I06_RS20915 944077..944997 - 921 WP_042327934.1 DMT family transporter -
I6I06_RS20920 945099..945980 + 882 WP_042327935.1 LysR family transcriptional regulator -
I6I06_RS20925 946002..947057 - 1056 WP_042327936.1 ABC transporter ATP-binding protein -
I6I06_RS20930 947145..948746 - 1602 WP_042327937.1 iron ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-81)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9972.40 Da        Isoelectric Point: 8.4614

>T183869 WP_042327933.1 NZ_CP066076:943743-943994 [Paraburkholderia ginsengisoli]
MFTDDAWDDYLYWQETDRKVLRKINTLLEECRRDPYRGTGKPEALIGSLSGLWSRRITLADRLVYLPRDGKIYVIACRFH
YDR

Download         Length: 252 bp

>T183869 NZ_CP087197:c5426358-5426185 [Pseudomonas sp. B21-012]
GTGCGCCCTGGAAAACCAATAAGTGTGTATGGTGTGTATGATGTCGGAGCGAAGGGCAGTCACCACCAGTTCAAGCATCC
AACCAAATCCGGCAGGGTCACAGTGCCCCACCCCAAGAGCGATATTCCAAAAGGAACCCTGAACAACATACTGAAGACCG
CCGGCCTCAAGTGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10675.12 Da        Isoelectric Point: 9.7591

>AT183869 WP_042327932.1 NZ_CP066076:943439-943732 [Paraburkholderia ginsengisoli]
MNVLTYSEARAGFKQAMDDVCRDHTPMLITRQSGENVVMVSLDDFNAMQETLYLLSSSKNAQRLARSIAQLNAGSATARK
LLTDEPTKKPQRGGRTG

Download         Length: 294 bp

>AT183869 NZ_CP087197:c5426116-5425694 [Pseudomonas sp. B21-012]
ATGAAGTTTCCAGTGGTCATCCACAAAGACCCTGAATCTGACTATGGCGTAACGGTACCGGACGTCGCGGGCTGCTTCTC
TGCAGGCGAGACCGTCGAGGAAGCATTGGACAACGTCCAGGAGGCGCTGGCCCTGCATTTCGAATCACTGGTCACCGATG
AAGAGCCATTGCCTCAGGGCCAGGCTATTGATGCTCATATGGGCAATCCCGATTATGCGGGTGGTGTGTGGGCGGTCGTT
GATTTCGACGTGACCCCATACTTGGGTAAGTCGGTACGGTTCAATGCATCTCTGCCGGAGTTTCTGCTGCAACGCATCGA
CAACTATGTGAAGAATCACCCAGAACAGAAAAGCCGTTCGGGGTTCCTGGCGTCAGCAGCGTTGCGCGTACTGCAAGAAA
CGTCCCCCAACGTAAGAACATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7T4N9K7

Antitoxin

Source ID Structure
AlphaFold DB A0A7T4TBV9

References