Detailed information of TA system TA183853

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-sprA1AS/-
• Location: 24718..24866
• Replicon: plasmid unnamed
• Accession: NZ_CP066063
• Organism: Staphylococcus pettenkoferi strain FDAARGOS_1071

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: -
• Locus tag: I6I28_RS11895
• Protein ID: WP_011276848.1
• Coordinates: 24771..24866 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	24718..24753 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
I6I28_RS11870	21483..21887	+	405	WP_002470938.1	hypothetical protein	-
I6I28_RS11875	21915..22277	+	363	WP_002470940.1	DUF2294 domain-containing protein	-
I6I28_RS11880	22366..23040	-	675	WP_102696178.1	IS6 family transposase	-
I6I28_RS11885	23401..23829	-	429	WP_070502625.1	Rrf2 family transcriptional regulator	-
I6I28_RS11890	23943..24416	-	474	Protein_27	hypothetical protein	-
-	24718..24753	-	36	NuclAT_0	-	Antitoxin
I6I28_RS11895	24771..24866	-	96	WP_011276848.1	type I toxin-antitoxin system Fst family toxin	Toxin
I6I28_RS11900	25033..25380	-	348	WP_002467551.1	metalloregulator ArsR/SmtB family transcription factor	-
I6I28_RS11905	25399..26016	-	618	WP_070502627.1	CadD family cadmium resistance transporter	-
I6I28_RS11910	26672..27280	-	609	Protein_31	protein rep	-
I6I28_RS11915	27324..27998	+	675	WP_012263520.1	IS6-like element IS257 family transposase	-
I6I28_RS11920	28050..28205	+	156	Protein_33	IS3 family transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Mobilizable plasmid	vga(A)	-	1..44233	44233
	-	inside	IScluster/Tn	-	-	22366..27998	5632

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3623.38 Da
• Isoelectric Point: 9.5124

>T183853 WP_011276848.1 NZ_CP066063:c24866-24771 [Staphylococcus pettenkoferi]
MLEILVHITTTVISGCIIALFTHWLRNRKDK

Nucleotide

• Length: 96 bp

>T183853 NZ_CP087194:c1109780-1109526 [Pseudomonas sp. B21-017]
ATGAATATCGAGTTCACTCCTGAAGGCTGGGACGACTATTTGTGGTTTCAGCAAAACGATAAGGCCGGGCTCAAACGAAT
CAACCTGCTGATCAAGGCGATCCTGCGTGAGCCCTTCGAAGGATTGGGCAAACCTGAACCGCTCAAACACAATCTGAGCG
GCCTCTGGTCACGCCGAATCACCTCCGAGCATCGCCTGGTTTATGCAATCGAGAATGGTGAGGTGCGCATCGTGCTTTGC
AGGTATCACTACTGA

Antitoxin

Nucleotide

• Length: 36 bp

>AT183853 NZ_CP066063:c24753-24718 [Staphylococcus pettenkoferi]
TACAAAAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin