Detailed information of TA system TA183761

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 610408..610667
• Replicon: chromosome
• Accession: NZ_CP066013
• Organism: Staphylococcus equorum strain FDAARGOS_1068

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: I6I25_RS03195
• Protein ID: WP_002511402.1
• Coordinates: 610408..610515 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF1
Locus tag	-
Coordinates	610505..610667 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
I6I25_RS03165	605640..606512	+	873	WP_002507156.1	ABC transporter ATP-binding protein	-
I6I25_RS03170	606512..607240	+	729	WP_002507157.1	ABC transporter permease subunit	-
I6I25_RS03175	607323..607883	-	561	WP_002507158.1	thioredoxin family protein	-
I6I25_RS03180	608054..608539	+	486	WP_021339981.1	hypothetical protein	-
I6I25_RS03185	608634..609194	+	561	WP_002511403.1	DUF1700 domain-containing protein	-
I6I25_RS03190	609191..610042	+	852	WP_021339982.1	DUF4097 family beta strand repeat protein	-
I6I25_RS03195	610408..610515	+	108	WP_002511402.1	putative holin-like toxin	Toxin
-	610505..610667	-	163	-	-	Antitoxin
I6I25_RS03200	610803..610973	-	171	WP_021339983.1	tyrosine-type recombinase/integrase	-
I6I25_RS03205	611281..612321	-	1041	WP_021339984.1	choloylglycine hydrolase	-
I6I25_RS03210	612816..612986	+	171	WP_002507168.1	hypothetical protein	-
I6I25_RS03215	613090..613269	+	180	WP_064782805.1	hypothetical protein	-
I6I25_RS03220	613262..613441	+	180	WP_064782806.1	hypothetical protein	-
I6I25_RS03225	613496..613906	-	411	WP_002507169.1	YolD-like family protein	-
I6I25_RS03230	614083..615120	+	1038	WP_021339833.1	lactonase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (4-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3756.72 Da
• Isoelectric Point: 10.4997

>T183761 WP_002511402.1 NZ_CP066013:610408-610515 [Staphylococcus equorum]
VVPIVEALHLMLGFGTFIVTLLGLVVAIVKLSHKK

Nucleotide

• Length: 108 bp

>T183761 NZ_CP087176:2935061-2935342 [Pseudomonas sp. B21-040]
ATGACCTATGAGCTGGAATTCTCTGAAAAAGCGTGGAAAGAATGGCAAAAGCTGGGGGGCAACCTAAGGGAGCAGTTCAA
AAGGAAGCTTCAGGAGCGACTGCTTAATCCGCATGTTCCCGCAGACCGGCTAAGCGGGCTTGGAAATGCTTACAAGATCA
AGCTACGTGGTGCTGGATACAGGATGGTTTATCGAGTGAAGGACGAGGTGTTGATAGTGACTGTCATCGCCGTGGGGAAA
CGAGAACGGGGCGATGTTTACAAAAATGCAGGCGATCGCTGA

Antitoxin

Nucleotide

• Length: 163 bp

>AT183761 NZ_CP066013:c610667-610505 [Staphylococcus equorum]
ATTTGATAATATTTTTATGTTGTGGTAATTTATATATAGAAAAAGGGCAACACACCATAAGTGTATCGCCCTAATGAGCC
CGTTAAAAAGACGGTGGCTGGAATTTAATAATGATTAAATAATCATCTCATCCTCGCCAAAGTTAGAGATGGTTATTTTT
TAT

Structures

Antitoxin