Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 178715..179238 Replicon chromosome
Accession NZ_CP065921
Organism Staphylococcus pseudintermedius strain SP_11304-3A

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag JC286_RS00790 Protein ID WP_063278654.1
Coordinates 178972..179238 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag JC286_RS00785 Protein ID WP_198461263.1
Coordinates 178715..178972 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JC286_RS00765 174054..174236 - 183 WP_063278657.1 hypothetical protein -
JC286_RS00770 174763..175569 + 807 WP_198461261.1 arylamine N-acetyltransferase -
JC286_RS00775 175863..176357 - 495 WP_015729749.1 membrane protein -
JC286_RS00780 176617..178521 + 1905 WP_143951594.1 triacylglycerol lipase -
JC286_RS00785 178715..178972 + 258 WP_198461263.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
JC286_RS00790 178972..179238 + 267 WP_063278654.1 Txe/YoeB family addiction module toxin Toxin
JC286_RS00795 179599..179700 - 102 WP_019169745.1 DUF2648 domain-containing protein -
JC286_RS00800 179714..181207 - 1494 WP_014612817.1 malate dehydrogenase (quinone) -
JC286_RS00805 181964..182065 + 102 Protein_159 KxYKxGKxW signal peptide domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(9-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-68)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10539.11 Da        Isoelectric Point: 10.2281

>T183602 WP_063278654.1 NZ_CP065921:178972-179238 [Staphylococcus pseudintermedius]
MGNYSVLIKNSAKNDLKKIKKPLLKEQFSKIIEVLKINPYEASQSFEKLQPKHSARYSRRLNHQHRVVYTVDDEKREVYI
FSAWSHYE

Download         Length: 267 bp

>T183602 NZ_CP087123:5525726-5526196 [Klebsiella pneumoniae]
GTGATCCTCTACAGGCTGACGAAAACAAAGTATCTTTCTACGGCCTGGACCGGATATGGTGCGAAAGAGGCTGGTGGGCG
TTGGAATAGCGTGGGGGTGTCAATGGTATATGTCTCCGAAACGGCATCACTAACGATGCTGGAGACGCTGGTACACCTGC
ATGCGGCACAGATAATGGACTCTTTCACGCTACTGAGTATCGATGTGCCTGATGAACTGATCCAAAGCGCAAACATGGAT
GAATTACCGGGCAACTGGGCTGATGAGGATGCGCCTCAGGAACTGGCTGATTACGGAGATGCCTGGTCATTTACCAGGAG
CTCGGTTGCACTGCGTGTTCCCTCAGCCTTATCGCCGGTAGAGTTCAACTATCTGTTAAATCCTGAGCACCCTGAGTTTT
ACGGGATCGTGCAGAAGGCTCAACAGATACCGTTCCGGTTTGATAGTCGTCTTAAACCTGACAGGAAGTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9880.90 Da        Isoelectric Point: 4.1207

>AT183602 WP_198461263.1 NZ_CP065921:178715-178972 [Staphylococcus pseudintermedius]
MIIKTPTNARKEFYELLKQVNDNHEPIIISGSKSENNAVIVSQEDWDSIQETLFLEYTGTMDKVRAREKDDSGYTNIEDI
DWDNL

Download         Length: 258 bp

>AT183602 NZ_CP087123:5525286-5525729 [Klebsiella pneumoniae]
ATGAAAACATTTAGTTTGTCCTCAACTCCAGCCAGACCACAGCGCCTCTGGCAGGTTGCCGGGTTAAATAATGCTGATGG
CGTAGCGCTTCTGGGCCAAATCAATGAAGGCCTGGACGGGAAGGTGGCGAATCGGATCACTGACTGGGCCAGAATAACCC
AGAATGACCTGAGAAAAATGTCCGGTATCCCGTCGACCACGTTTAGCCGCAGTGTGAAGGCACGTTTTAACCCGGAACAA
AGTGAACGTCTGGTACGGATTATCCGCGTCATTGATCGGGCGGTAGATTTGTTTGAAGGCGACAAGGAAGCCGCACAGAA
GTGGTTGAACGAACCTAACCGGGCATTGAGCTGGAAAGTGCCAGCAGACCTGATGGCATCCGAGACAGGAGCGTATGAGG
TCATTAAGCTGATTACGCGTCTGGAGCATGGGGTGTACTCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References