Detailed information of TA system TA183415

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): higBA (relBE)/-
• Location: 4041526..4042183
• Replicon: chromosome
• Accession: NZ_CP065824
• Organism: Pseudomonas tolaasii strain Pt11

Toxin (Protein)

• Gene name: higB
• Uniprot ID: -
• Locus tag: I7845_RS17755
• Protein ID: WP_017255234.1
• Coordinates: 4041526..4041876 (+)
• Length: 117 a.a.

Antitoxin (Protein)

• Gene name: higA
• Uniprot ID: A0A7Y8ALG3
• Locus tag: I7845_RS17760
• Protein ID: WP_017255233.1
• Coordinates: 4041866..4042183 (+)
• Length: 106 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
I7845_RS17740 (I7845_17740)	4037855..4038799	+	945	WP_016974040.1	ABC transporter permease	-
I7845_RS17745 (I7845_17745)	4038799..4039683	+	885	WP_016974039.1	ABC transporter permease	-
I7845_RS17750 (I7845_17750)	4039707..4041302	+	1596	WP_177037920.1	gamma-glutamyltransferase family protein	-
I7845_RS17755 (I7845_17755)	4041526..4041876	+	351	WP_017255234.1	toxin	Toxin
I7845_RS17760 (I7845_17760)	4041866..4042183	+	318	WP_017255233.1	XRE family transcriptional regulator	Antitoxin
I7845_RS17765 (I7845_17765)	4042239..4042898	-	660	WP_016974036.1	type VI secretion system-associated protein TagF	-
I7845_RS17770 (I7845_17770)	4042908..4046471	-	3564	WP_218819230.1	type VI secretion system membrane subunit TssM	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 117 a.a.
• Molecular weight: 13728.61 Da
• Isoelectric Point: 9.3839

>T183415 WP_017255234.1 NZ_CP065824:4041526-4041876 [Pseudomonas tolaasii]
MGALFIELPAFERHRKDYLSDELFHGFQQELMKNPEAGDVIEGTSGLRKVRFVDERRNKGKRGGLRVIYYWWSGGTQFWL
FTLYGKHEQDDLTPHHKKALKHMLDREIKARAHDET

Nucleotide

• Length: 351 bp

>T183415 NZ_CP086982:c166126-165875 [Pseudosulfitobacter pseudonitzschiae]
ATGGATGTTATGACCTATTCAGACGCACGAGCTCAACTGAAGGGCGTCATGGATCGAGCGATCCACGACAAGCAAGAAGT
TGTTGTGACGCGCAAAAAAGGAGAGTCCGTCGTGGTCGTATCCTTGGAAACCTGGAACGCCGTAAATGAGACGCTGCACC
TCCTGTCCACACCAAAAAACGCATCCCGCTTGCGCGCGTCGATCGCGCAACTCGATGCTGGAACTGGCGAAGTGCGTGAG
CTGACCGAGTGA

Antitoxin

Protein

• Length: 106 a.a.
• Molecular weight: 11901.72 Da
• Isoelectric Point: 10.3438

>AT183415 WP_017255233.1 NZ_CP065824:4041866-4042183 [Pseudomonas tolaasii]
MKREIFSELVEGFDALADERQGKITLRTHKVHLNKLEPLTAEEVVAVRQQLNLSRSVFAMYLRTNTRTLENWEQGRAKPN
AQAVTLIRLVARFPETVAQLAALGS

Nucleotide

• Length: 318 bp

>AT183415 NZ_CP086982:c165878-165612 [Pseudosulfitobacter pseudonitzschiae]
GTGAAGTTGGTTTTTTCCGATCAGGCTTGGGAAGACTATCAGTACTGGGTCAACACCAACGACAAGGTACGTGACCGGAT
CAACGAGCTGATCAAGCAGTGCAGGCGGACCCCTTTCAAAGGAACCGGCAAGCCGGAACCTTTGAAGGGCGATCTGACCG
GCTGGTGGTCACGGCGGATTTCTCAGGAAGATCGAATGGTCTACCGGGTTAGTGGAACTGGCGACGGCCAAAGCCTAGAG
ATTGCACAACTGCGGTTTCATTACTGA

Structures

Antitoxin

• AlphaFold DB: A0A7Y8ALG3