Detailed information of TA system TA183374

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): bsrE-as-bsrE/-
• Location: 2069489..2069735
• Replicon: chromosome
• Accession: NZ_CP065789
• Organism: Bacillus subtilis strain LBUM979

Toxin (Protein)

• Gene name: bsrE
• Uniprot ID: -
• Locus tag: I8N71_RS10335
• Protein ID: WP_109789044.1
• Coordinates: 2069489..2069581 (+)
• Length: 31 a.a.

Antitoxin (RNA)

Gene name	as-bsrE
Locus tag	-
Coordinates	2069562..2069735 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
I8N71_RS10320	2064648..2064983	+	336	WP_009967409.1	hypothetical protein	-
I8N71_RS10325	2065030..2068635	-	3606	WP_004399367.1	membrane protein	-
I8N71_RS10330	2068868..2069200	-	333	WP_026009814.1	hypothetical protein	-
I8N71_RS10335	2069489..2069581	+	93	WP_109789044.1	type I toxin-antitoxin system toxin BsrE	Toxin
-	2069562..2069735	-	174	-	-	Antitoxin
I8N71_RS10340	2069850..2070692	-	843	WP_003231327.1	hypothetical protein	-
I8N71_RS10345	2070892..2071350	-	459	WP_003231326.1	type II toxin-antitoxin system antitoxin YobK	-
I8N71_RS10350	2071360..2073162	-	1803	WP_004399481.1	type II toxin-antitoxin system toxin ribonuclease YobL	-
I8N71_RS10355	2073264..2073821	-	558	WP_004399321.1	SMI1/KNR4 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2055474..2080700	25226

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-24)

Sequences

Toxin

Protein

• Length: 31 a.a.
• Molecular weight: 3358.16 Da
• Isoelectric Point: 4.1840

>T183374 WP_109789044.1 NZ_CP065789:2069489-2069581 [Bacillus subtilis]
MSTFQALMLMLAIGSFIIALLTYIEKIDLP

Nucleotide

• Length: 93 bp

>T183374 NZ_CP086943:c32180-31905 [Pseudosulfitobacter pseudonitzschiae]
GTGCCTGACCTTGAATGGAAGGCATTGGCGGTCGCGGACCTGATGGCGATTGTTGACTATATCTCGGATGACAATCCCGA
TGCCGCAATTTCCCTGATGGATGACATTCAAGACAAGGTGCTTGGCCTTCTGACGCATCCCAAATCCGGCCGCCCCGGTA
GGGTGAACGACACGCGAGAGCTGGTGATCCGGCCCAACTATATCGTCGTCTATGCTGAAAACACGGCGGCGGTCACCATT
CTGCGCGTTCTTCATGCGGTGCAGATGTGGCCCTGA

Antitoxin

Nucleotide

• Length: 174 bp

>AT183374 NZ_CP065789:c2069735-2069562 [Bacillus subtilis]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Structures

Antitoxin