Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) sprG-sprF/-
Location 1776651..1776910 Replicon chromosome
Accession NZ_CP065710
Organism Staphylococcus equorum strain FDAARGOS_884

Toxin (Protein)


Gene name SprG2 Uniprot ID -
Locus tag I6G41_RS09190 Protein ID WP_002511402.1
Coordinates 1776803..1776910 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 1776651..1776813 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6G41_RS09160 1772108..1772278 - 171 WP_002507168.1 hypothetical protein -
I6G41_RS09165 1772773..1773813 + 1041 WP_002507167.1 choloylglycine hydrolase -
I6G41_RS09170 1774396..1775046 - 651 WP_002507165.1 cytochrome P450 -
I6G41_RS09175 1775024..1775317 - 294 WP_040762580.1 hypothetical protein -
I6G41_RS09180 1775427..1775582 - 156 WP_002507163.1 hypothetical protein -
I6G41_RS09185 1775602..1776345 - 744 WP_002507162.1 HAD-IIB family hydrolase -
- 1776651..1776813 + 163 - - Antitoxin
I6G41_RS09190 1776803..1776910 - 108 WP_002511402.1 putative holin-like toxin Toxin
I6G41_RS09195 1777267..1778118 - 852 WP_002507161.1 DUF4097 family beta strand repeat protein -
I6G41_RS09200 1778115..1778675 - 561 WP_002511403.1 DUF1700 domain-containing protein -
I6G41_RS09205 1778744..1779250 - 507 WP_197910790.1 hypothetical protein -
I6G41_RS09210 1779421..1779981 + 561 WP_002507158.1 thioredoxin family protein -
I6G41_RS09215 1780064..1780792 - 729 WP_002507157.1 ABC transporter permease subunit -
I6G41_RS09220 1780792..1781664 - 873 WP_002507156.1 ABC transporter ATP-binding protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(4-35)


Sequences


Toxin        


Download         Length: 36 a.a.        Molecular weight: 3756.72 Da        Isoelectric Point: 10.4997

>T183256 WP_002511402.1 NZ_CP065710:c1776910-1776803 [Staphylococcus equorum]
VVPIVEALHLMLGFGTFIVTLLGLVVAIVKLSHKK

Download         Length: 108 bp

>T183256 NZ_CP086828:30088-30363 [Pseudosulfitobacter pseudonitzschiae]
GTGCCTGACCTTGAATGGAAGGCATTGGCGGTCGCGGACCTGATGGCGATTGTTGACTATATCTCGGATGACAATCCCGA
TGCCGCAATTTCCCTGATGGATGACATTCAAGACAAGGTGCTTGGCCTTCTGACGCATCCCAAATCCGGCCGCCCCGGTA
GGGTGAACGACACGCGAGAGCTGGTGATCCGGCCCAACTATATCGTCGTCTATGCTGAAAACACGGCGGCGGTCACCATT
CTGCGCGTTCTTCATGCGGTGCAGATGTGGCCCTGA

Antitoxin


Download         Length: 163 bp

>AT183256 NZ_CP065710:1776651-1776813 [Staphylococcus equorum]
ATTTGATAATATTTTTATGTTGTGGTAATTTATATATAGAAAAAGGGCAACACACCATAAGTGTATCGCCCTAATGAGCC
CGTTAAAAAGACGGTGGCTGGAATTTAATAATGATTAAATAATCATCTCATCCTCGCCAAAGTTAGAGATGGTTATTTTT
TAT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References