183145

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 5168670..5169487 Replicon chromosome
Accession NZ_CP065668
Organism Delftia acidovorans strain FDAARGOS_909

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag I6G66_RS24275 Protein ID WP_183021074.1
Coordinates 5168670..5169161 (-) Length 164 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag I6G66_RS24280 Protein ID WP_016448384.1
Coordinates 5169158..5169487 (-) Length 110 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6G66_RS24250 5163900..5164325 + 426 WP_183021078.1 type II toxin-antitoxin system VapC family toxin -
I6G66_RS24255 5164364..5165413 - 1050 WP_183021077.1 NAD(P)-dependent alcohol dehydrogenase -
I6G66_RS24260 5165555..5166448 + 894 WP_183021076.1 LysR family transcriptional regulator -
I6G66_RS24265 5166606..5168027 + 1422 WP_183021075.1 chloride channel protein -
I6G66_RS24270 5168143..5168655 + 513 WP_012207634.1 MgtC/SapB family protein -
I6G66_RS24275 5168670..5169161 - 492 WP_183021074.1 type II toxin-antitoxin system YhaV family toxin Toxin
I6G66_RS24280 5169158..5169487 - 330 WP_016448384.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
I6G66_RS24285 5169584..5171827 - 2244 WP_197954904.1 TonB-dependent receptor -
I6G66_RS24290 5171938..5172342 - 405 WP_197954905.1 hypothetical protein -
I6G66_RS24295 5172371..5173033 - 663 WP_197954908.1 pyridoxamine 5'-phosphate oxidase family protein -
I6G66_RS24300 5173104..5173937 + 834 WP_183021070.1 helix-turn-helix transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(16-152)

Antitoxin

PrlF antitoxin

(8-107)


Sequences

Toxin        


Download         Length: 164 a.a.        Molecular weight: 18763.41 Da        Isoelectric Point: 10.3625

>T183145 WP_183021074.1 NZ_CP065668:c5169161-5168670 [Delftia acidovorans]
MSAVPPAPLRIHGWTVFMHPLFLAQLQALSQEVEGLKTKDPGGYTRKNATKRLAAIRKLAFDVIPQDPTRPDYRQGHTLG
EEHKHWFRARFFQQYRLFFRFHVPSKIIVFAWVNDEDTKQAYEGSDDAYRVFRKMLANGHPPGDWDSLLAQAKSPPSRSP
PHA

Download         Length: 492 bp

>T183145 NZ_CP086724:344833-345201 [Klebsiella pneumoniae]
ATGACGCTGCAGATTATCTCAGCGGAAGAGATAATACAGTTTCACGACAGGCTGCTCCGCGTCACGCCTGGCGTTGCCGG
TATGCCCGATCCGGGGCGTGCCGAAGCGATAATGTATAGGGTGCTAAACAAAATTGAATATGAAGGTGTGACAGACGTGT
GGCGACTCGCTGCGATGCATCTGCTGGCGATTTCTCGCGGTCATATATTTAATGATGGTATTAAGCGTACGGCACTGTTT
ATCACCCTGCTTTTTTTAAAGCGAAATGGAATTATATTGCCAGCGAATCCAGACTTCGTCGGCATGACCGTCGAGGCAGC
AGCAGGGCAACTTACCCTGGAACAGATTGTCGCGCGTTTGCGCGGATGA

Antitoxin


Download         Length: 110 a.a.        Molecular weight: 12062.53 Da        Isoelectric Point: 4.1858

>AT183145 WP_016448384.1 NZ_CP065668:c5169487-5169158 [Delftia acidovorans]
MFSTLEAESTLTDRYQTTIPEAVRRALHLSKRDRIHYTILPGGEVVLSRADSAEDADPVLGQFLGFLAQDMAAHPERLQT
MDARLAQQIQALTEGIEVDLDAPLLADDE

Download         Length: 330 bp

>AT183145 NZ_CP086724:344615-344836 [Klebsiella pneumoniae]
ATGAGAACGGTTAACTATAGCGAAGCCCGGCAAAATCTGGCCGATGTGCTGGAAAGCGCAGTGACAGGTGTACCTGTGAC
CATTACCCGTCGTGGGCATAAATCTGCAGTCATCATTAGTGCAGAAGAGTTTGAACGCTACCAGGCGGCCAGAATGGATG
ATGAGTTCGCGGCTATCATGGCGGTTCATGGTGATGAGATCAGGGAGCTTGCGGATAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References