Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 916098..916915 Replicon chromosome
Accession NZ_CP065627
Organism Delftia acidovorans strain FDAARGOS_939

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag I6G96_RS04125 Protein ID WP_123695671.1
Coordinates 916424..916915 (+) Length 164 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag I6G96_RS04120 Protein ID WP_197944355.1
Coordinates 916098..916427 (+) Length 110 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6G96_RS04100 911637..912470 - 834 WP_197944351.1 helix-turn-helix transcriptional regulator -
I6G96_RS04105 912541..913203 + 663 WP_197944352.1 pyridoxamine 5'-phosphate oxidase family protein -
I6G96_RS04110 913232..913636 + 405 WP_197944353.1 hypothetical protein -
I6G96_RS04115 913760..916000 + 2241 WP_197944354.1 TonB-dependent receptor -
I6G96_RS04120 916098..916427 + 330 WP_197944355.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
I6G96_RS04125 916424..916915 + 492 WP_123695671.1 type II toxin-antitoxin system YhaV family toxin Toxin
I6G96_RS04130 916930..917442 - 513 WP_012207634.1 MgtC/SapB family protein -
I6G96_RS04135 917558..919003 - 1446 WP_197944356.1 chloride channel protein -
I6G96_RS04140 919161..920054 - 894 WP_013800520.1 LysR family transcriptional regulator -
I6G96_RS04145 920196..921245 + 1050 WP_197944357.1 NAD(P)-dependent alcohol dehydrogenase -
I6G96_RS04150 921284..921709 - 426 WP_180318716.1 type II toxin-antitoxin system VapC family toxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(16-152)

Antitoxin

PrlF antitoxin

(8-107)


Sequences

Toxin        


Download         Length: 164 a.a.        Molecular weight: 18735.36 Da        Isoelectric Point: 10.4933

>T183090 WP_123695671.1 NZ_CP065627:916424-916915 [Delftia acidovorans]
MSAAPPAPLRIHGWTVFMHPLFLAQLQALSQEVEGLKTKDPGGYTRKNATKRLAAIRKLAFDVIPQDPTRPDYRQGHTLG
EEHKHWFRARFFQQYRLFFRFHAPSKIIVFAWVNDEDTKRAYEGSDDAYRVFRKMLANGHPPGDWDSLLAQAKSPPSRSP
PHA

Download         Length: 492 bp

>T183090 NZ_CP086662:c2727383-2727153 [Escherichia coli]
CTGGATCAGCTATTTAAATCACCTTTACCTCAAGGAATCAAATGGACTGATATAGAATCTCTGGTTAAAGCGTTAGGCGG
AGAAATTAAGGAAGGTAGGGGGTCGCGCTGTAAGTTCATACTAAATATGAGCGTTGCGTGTTTCCATCGGCCTCATCCGT
CGCCAGATACCGATAAAGGCGCTGTAGAAAGCGTGCGTGACTGGTTACTAAGTATAGGGGTAAAACCATGA

Antitoxin


Download         Length: 110 a.a.        Molecular weight: 12092.56 Da        Isoelectric Point: 4.1858

>AT183090 WP_197944355.1 NZ_CP065627:916098-916427 [Delftia acidovorans]
MFSTLEAESTLTDRYQTTIPEAVRRALHLSKRDRIHYTILPGGEVVLSRADSAEDADPVLGQFLGFLAQDMATHPERLQT
MDARLAQQIQALTEGIEVDLDAPLLADDE

Download         Length: 330 bp

>AT183090 NZ_CP086662:c2727156-2726797 [Escherichia coli]
ATGATCAAACTGAAGACGCCAAACTCTATGGAGATTGCCGGGCAACCTGCTGTTATCACTTACGTGCCAGAACTGAATGC
ATTTCGTGGCAAATTCCTGGGCTTGTCAGGTTATTGTGATTTTGTCTCTGACAGCATTCAGGGGCTGCAAAAAGAAGGGG
AACTTTCCCTGCGAGAGTATCTTGAGGATTGTAAAGCTGCGGGTATTGAGCCGTATGCGCGTACAGAAAAGATTAAGACC
TTTACGTTACGCTATCCAGAATCGCTGAGTGAACGCCTTAATAATGCGGCTGCGCAGCAACAAGTCTCTGTTAATACCTA
TATTATTGAAACACTGAATGAGCGTTTGAATCATTTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References