Detailed information of TA system TA182460

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprG3-sprA1AS/-
• Location: 2130971..2131169
• Replicon: chromosome
• Accession: NZ_CP065354
• Organism: Staphylococcus aureus strain JW_comp_novo

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: -
• Locus tag: I5044_RS10395
• Protein ID: WP_078064523.1
• Coordinates: 2131065..2131169 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	2130971..2131009 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
I5044_RS10375 (I5044_10375)	2127082..2127747	-	666	WP_001024086.1	SDR family oxidoreductase	-
I5044_RS10380 (I5044_10380)	2127899..2128219	+	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
I5044_RS10385 (I5044_10385)	2128221..2129201	+	981	WP_000019746.1	CDF family zinc efflux transporter CzrB	-
I5044_RS10390 (I5044_10390)	2129467..2130558	+	1092	WP_000495687.1	hypothetical protein	-
I5044_RS13455	2130951..2131025	+	75	Protein_2013	hypothetical protein	-
-	2130971..2131009	+	39	-	-	Antitoxin
I5044_RS10395 (I5044_10395)	2131065..2131169	-	105	WP_078064523.1	hypothetical protein	Toxin
I5044_RS10400 (I5044_10400)	2131330..2131813	-	484	Protein_2015	recombinase family protein	-
I5044_RS10405 (I5044_10405)	2131856..2132992	-	1137	WP_000115566.1	SAP domain-containing protein	-
I5044_RS10410 (I5044_10410)	2133281..2133373	+	93	WP_031844941.1	hypothetical protein	-
I5044_RS10415 (I5044_10415)	2134076..2134933	-	858	WP_029753951.1	HAD family hydrolase	-
I5044_RS10420 (I5044_10420)	2135001..2135783	-	783	WP_000908184.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3906.77 Da
• Isoelectric Point: 5.5724

>T182460 WP_078064523.1 NZ_CP065354:c2131169-2131065 [Staphylococcus aureus]
MLILERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

>T182460 NZ_CP086464:c5374608-5374225 [Klebsiella pneumoniae]
ATGACCTCCGGATCTGCGCTTTTTGATACCAATATTCTTATTGATTTATTTAGCGGGCGTCGCGAAGCCAAACAGGCGCT
GGAGGCCTGGCCACCGCAGAATGCGATCAGTCTGATTACCTGGATGGAGGTGATGGTTGGCGCTAAAAAATATCACCAGG
AGCAGCGCACGCGAATGGCGCTGAGCACCTTTAATATCATTAACATCTCACAGGATATTGCAGAGCGAAGCGTTGCGCTG
CGGCAGGAGTATAAGCTTAAGCTGCCGGATGCCATCATTCTGGCGACGGCGCAACTCCATCGTCTGGAACTAATTACGCG
GAATACGAAGGATTTTGCCGGTATTCCTGGCGTAGTCACGCCGTACGAAATCCACCCTGAATAA

Antitoxin

Nucleotide

• Length: 39 bp

>AT182460 NZ_CP065354:2130971-2131009 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Structures

Antitoxin