Detailed information of TA system TA182280

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): prlF-yhaV (relBE)/YhaV-PrlF
• Location: 3886827..3887662
• Replicon: chromosome
• Accession: NZ_CP065178
• Organism: Pectobacterium quasiaquaticum strain A398-S21-F17

Toxin (Protein)

• Gene name: yhaV
• Uniprot ID: -
• Locus tag: IG605_RS17875
• Protein ID: WP_193407402.1
• Coordinates: 3886827..3887312 (-)
• Length: 162 a.a.

Antitoxin (Protein)

• Gene name: prlF
• Uniprot ID: -
• Locus tag: IG605_RS17880
• Protein ID: WP_180785957.1
• Coordinates: 3887318..3887662 (-)
• Length: 115 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IG605_RS17855 (IG605_017795)	3882403..3883812	-	1410	WP_193407400.1	FtsX-like permease family protein	-
IG605_RS17860 (IG605_017800)	3883809..3884501	-	693	WP_193407401.1	ABC transporter ATP-binding protein	-
IG605_RS17865 (IG605_017805)	3884510..3884989	-	480	WP_039277140.1	hypothetical protein	-
IG605_RS17870 (IG605_017810)	3885002..3886747	-	1746	WP_010277828.1	alkaline phosphatase	-
IG605_RS17875 (IG605_017815)	3886827..3887312	-	486	WP_193407402.1	type II toxin-antitoxin system YhaV family toxin	Toxin
IG605_RS17880 (IG605_017820)	3887318..3887662	-	345	WP_180785957.1	type II toxin-antitoxin system PrlF family antitoxin	Antitoxin
IG605_RS17885 (IG605_017825)	3887856..3888011	-	156	WP_193399198.1	efflux RND transporter permease subunit	-
IG605_RS17890 (IG605_017830)	3888123..3888530	-	408	WP_226373213.1	hypothetical protein	-
IG605_RS17895 (IG605_017835)	3888520..3889221	-	702	WP_039277137.1	hypothetical protein	-
IG605_RS17900 (IG605_017840)	3889252..3889731	-	480	WP_039277134.1	Hcp family type VI secretion system effector	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin endonuclease, YhaV (12-148)

Antitoxin

• PrlF antitoxin (15-113)

Sequences

Toxin

Protein

• Length: 162 a.a.
• Molecular weight: 18585.29 Da
• Isoelectric Point: 9.3227

>T182280 WP_193407402.1 NZ_CP065178:c3887312-3886827 [Pectobacterium quasiaquaticum]
MVDKRVINGWQLFTHPCFDAQFESLIVEVEQLRKKYPESYQKKQATKLLAAIVKVIRTEICGDPSQTKFRQGDTLGGGNK
HWFRAKFLGQYRLFFRYSERHKTIILAWVNDSDTKRAYGDQHDAYKVFSGMLASGNPPGDWEQLLAESHSEAMLTQMLVL
P

Nucleotide

• Length: 486 bp

>T182280 NZ_CP065178:c3887312-3886827 [Pectobacterium quasiaquaticum]
ATGGTTGATAAGCGAGTAATAAATGGGTGGCAGCTATTTACGCATCCTTGTTTTGATGCGCAGTTTGAGTCTCTTATTGT
TGAAGTTGAGCAACTGCGCAAGAAATATCCAGAATCTTACCAGAAAAAGCAGGCAACTAAGCTATTGGCTGCAATAGTCA
AAGTCATCCGTACTGAGATTTGTGGCGATCCGTCCCAAACGAAGTTTAGACAAGGCGATACGCTAGGCGGAGGTAACAAA
CATTGGTTCAGGGCAAAATTTCTGGGTCAGTATCGGTTATTTTTTCGCTATAGCGAGAGACATAAAACTATCATCCTTGC
CTGGGTCAATGATTCAGACACTAAACGAGCATATGGCGATCAGCATGATGCTTATAAAGTTTTTAGCGGCATGCTAGCAA
GCGGGAATCCGCCGGGAGATTGGGAGCAACTGCTCGCTGAATCCCATAGTGAGGCCATGCTTACGCAAATGCTCGTGCTG
CCGTAA

Antitoxin

Protein

• Length: 115 a.a.
• Molecular weight: 12845.46 Da
• Isoelectric Point: 4.4510

>AT182280 WP_180785957.1 NZ_CP065178:c3887662-3887318 [Pectobacterium quasiaquaticum]
MFDLKSADVLLRADSRLTARSQTTIPSSVRDAMNLQPGEYIHYSVLPGGQVLISRREEVIDDDPVIHHFLHFLAEDMQRH
PENIKPFDQSLMSRASVLTAGMDIDLDAPLTDDE

Nucleotide

• Length: 345 bp

>AT182280 NZ_CP065178:c3887662-3887318 [Pectobacterium quasiaquaticum]
ATGTTTGATTTAAAATCAGCGGATGTGTTGTTGCGCGCCGATAGTCGCTTAACGGCGCGTAGTCAGACAACGATTCCATC
GTCTGTGCGTGATGCAATGAACCTGCAACCTGGGGAGTACATTCATTATAGCGTGCTACCGGGGGGGCAAGTGCTGATCA
GTCGGCGTGAAGAGGTGATAGATGATGACCCCGTTATTCATCACTTTTTGCATTTTTTGGCTGAAGATATGCAACGTCAT
CCAGAAAATATTAAGCCGTTTGATCAATCGCTTATGTCACGTGCGAGTGTGTTAACCGCAGGGATGGATATTGATCTGGA
TGCACCGCTTACTGACGACGAGTGA