Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 4061695..4062530 Replicon chromosome
Accession NZ_CP065177
Organism Pectobacterium quasiaquaticum strain A477-S1-J17

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag IG609_RS18620 Protein ID WP_193399197.1
Coordinates 4061695..4062180 (-) Length 162 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag IG609_RS18625 Protein ID WP_180785957.1
Coordinates 4062186..4062530 (-) Length 115 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IG609_RS18600 (IG609_018585) 4057271..4058680 - 1410 WP_193399194.1 FtsX-like permease family protein -
IG609_RS18605 (IG609_018590) 4058677..4059369 - 693 WP_193399195.1 ABC transporter ATP-binding protein -
IG609_RS18610 (IG609_018595) 4059378..4059857 - 480 WP_039277140.1 hypothetical protein -
IG609_RS18615 (IG609_018600) 4059870..4061615 - 1746 WP_193399196.1 alkaline phosphatase -
IG609_RS18620 (IG609_018605) 4061695..4062180 - 486 WP_193399197.1 type II toxin-antitoxin system YhaV family toxin Toxin
IG609_RS18625 (IG609_018610) 4062186..4062530 - 345 WP_180785957.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
IG609_RS18630 (IG609_018615) 4062724..4062879 - 156 WP_193399198.1 efflux RND transporter permease subunit -
IG609_RS18635 (IG609_018620) 4062991..4063398 - 408 WP_226373213.1 hypothetical protein -
IG609_RS18640 (IG609_018625) 4063388..4064089 - 702 WP_039277137.1 hypothetical protein -
IG609_RS18645 (IG609_018630) 4064120..4064599 - 480 WP_039277134.1 Hcp family type VI secretion system effector -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4054259..4064599 10340


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(12-148)

Antitoxin

(15-113)


Sequences


Toxin        


Download         Length: 162 a.a.        Molecular weight: 18628.32 Da        Isoelectric Point: 9.5852

>T182260 WP_193399197.1 NZ_CP065177:c4062180-4061695 [Pectobacterium quasiaquaticum]
MVDKRVINGWQLFTHPCFDAQFESLIVEVEQLRKKYPESYQKKQATKLLAAIVKVIRTEICGDPSQTKFRQGDTLGGGNK
HWFRAKFLGQYRLFFRYSERHKTIILAWVNDSDTKRAYGDQHDAYKVFSGMLASGNPPGDWEQLLAESHSEAMLTQMLVR
P

Download         Length: 486 bp

>T182260 NZ_CP086370:211169-211507 [Massilia sp. HC52]
GTGACCGGCACCGCCTACGTCCCGGACGAAGGCGACATCGTCTGGATGAACTTCACCCCGCAAAGCGGCCACGAACAGGC
CGGCCGCCGCCCTGCCGTCGTCCTGTCGCCAAAATCCTACAATCTGCGCGCCGGCTTGCTGGTCTGCGTGCCGGTCAGTC
AAATCAAAGGCTATCCATTTGAAGTCGCCCTGACCGGCATGGGCGCAACCGGCGCCGCACTGGCGGACCAGGTAAAAAAC
GTGGACTGGCAGACCCGCAAGGCGGAACATAAAGGCAAGGCCAGCGCCGCCGAGATGGGCCAGATCCGCGCCAAAATCAA
AACCCTGCTGCGGCTATAA

Antitoxin


Download         Length: 115 a.a.        Molecular weight: 12845.46 Da        Isoelectric Point: 4.4510

>AT182260 WP_180785957.1 NZ_CP065177:c4062530-4062186 [Pectobacterium quasiaquaticum]
MFDLKSADVLLRADSRLTARSQTTIPSSVRDAMNLQPGEYIHYSVLPGGQVLISRREEVIDDDPVIHHFLHFLAEDMQRH
PENIKPFDQSLMSRASVLTAGMDIDLDAPLTDDE

Download         Length: 345 bp

>AT182260 NZ_CP086370:210930-211172 [Massilia sp. HC52]
ATGGCAAGGCAAGTACTCAAGAAGTGGGGCAACAGCACGGCGGTCCGGTTGCCCGCAGCGGTGATGGAAGCCGCCAATCT
GGCAGTCGACCAAGCCGTTGACGTGCGCGCTGAGCATGGGCGCGTCATTATCGAAGCGGCGGCGCCCATCTATCTGCTTG
ATGACCTGCTTGAAGGCATCACGCCGGAAAACCGCCACGGCGAGGTCGATACCGGCGCGCCGCAAGGCAAAGAGCTGCTG
TGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References