182252

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 2836375..2837035 Replicon chromosome
Accession NZ_CP065177
Organism Pectobacterium quasiaquaticum strain A477-S1-J17

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag IG609_RS13070 Protein ID WP_193398912.1
Coordinates 2836682..2837035 (-) Length 118 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag IG609_RS13065 Protein ID WP_010284412.1
Coordinates 2836375..2836677 (-) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IG609_RS13040 (IG609_013040) 2831487..2832923 - 1437 WP_193398906.1 6-phospho-beta-glucosidase -
IG609_RS13045 (IG609_013045) 2833137..2833592 - 456 WP_193398907.1 helix-turn-helix domain-containing protein -
IG609_RS13050 (IG609_013050) 2833659..2834915 + 1257 WP_193398909.1 MFS transporter -
IG609_RS13055 (IG609_013055) 2834930..2835280 - 351 WP_193398910.1 metalloregulator ArsR/SmtB family transcription factor -
IG609_RS13060 (IG609_013060) 2835333..2836337 + 1005 WP_193398911.1 threonine/serine dehydratase -
IG609_RS13065 (IG609_013065) 2836375..2836677 - 303 WP_010284412.1 helix-turn-helix transcriptional regulator Antitoxin
IG609_RS13070 (IG609_013070) 2836682..2837035 - 354 WP_193398912.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IG609_RS13075 (IG609_013075) 2837461..2838300 + 840 WP_193398913.1 glutathione-dependent disulfide-bond oxidoreductase -
IG609_RS13080 (IG609_013080) 2838419..2839390 - 972 WP_116227157.1 chemotaxis protein -
IG609_RS13085 (IG609_013085) 2840656..2841393 + 738 WP_193398914.1 LuxR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-106)

Antitoxin

Cro/C1-type helix-turn-helix domain

(33-81)


Sequences

Toxin        


Download         Length: 118 a.a.        Molecular weight: 13472.49 Da        Isoelectric Point: 9.8932

>T182252 WP_193398912.1 NZ_CP065177:c2837035-2836682 [Pectobacterium quasiaquaticum]
VWKIETTDVFDSWFGTLNDRDRAYVLAALIVLREKGPMLSRPYADTVKGSQYSNMKELRIQSGGMPIRAFFAFDPHRTGI
LLCAGNKSGNEKRFYDEMIPLADREFTKYLKKSEKRG

Download         Length: 354 bp

>T182252 NZ_CP086369:3395935-3396348 [Pectobacterium versatile]
GTGGCCCAGTGGCGATGTGACCTTCGCGTTTCCTGGCGCATGCAACTGCTGTCATTGGTGGTGCATGGCCTCTTAGTATT
ATTCATTCTGCTGGCACCGTGGCCGGACGGCTATGCGTGGCTATGGCTATGCCTGGTCACGATGGTGATGTTCGGTTTTA
TCCGTAGCCAAAGGAATATTAAATCCCGACAGGGGGAAATCGTTCTGCTCAGCGAAACGACCCTGAACTGGCGGCAGCAG
GAATGGCAAATCGTTAAACGACCGTGGCTGCTGAAGAATGGCGTGTTGCTGTCATTGCAGGCGGTTAACGCTAAAGACAA
GCAACAACTGTGGCTGGCATCGGACAGCATGGGCGATGACGAATGGCGTCACTTGCGTCAGCTTCTTTTGCAGCAGAAAC
ACTGGGCAAGATAG

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 11107.90 Da        Isoelectric Point: 6.2283

>AT182252 WP_010284412.1 NZ_CP065177:c2836677-2836375 [Pectobacterium quasiaquaticum]
MGRTLEQLLADEKPDVVVEAHAIAADMLLNIHLAELRERVQKTQVEMAQVLGLKQPTIAGMEKPGRDLKLSTLKRYVEAT
GSKLRLDVELPDGSHYGFTL

Download         Length: 303 bp

>AT182252 NZ_CP086369:3395688-3395954 [Pectobacterium versatile]
ATGGAAATCGATAATAAATCACGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAATTGGATATCGCGATCATGCCGTT
TTTTGAGCATGACTATGACACACTTAATGACACTGATAAGCGTACGTTTGTACGTTTGTTACAAAGCGACGATCCCGATT
TATTCAACTGGCTGATGAACCACGGTGAACCGAAGGACGGAGAGCTGAAACGCATGATTTCCCTTATTCAGACGCGAAAT
AAAGACCGTGGCCCAGTGGCGATGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References