Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 4124331..4124839 Replicon chromosome
Accession NZ_CP065037
Organism Leifsonia sp. ZF2019

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag IT072_RS20100 Protein ID WP_223358605.1
Coordinates 4124579..4124839 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag IT072_RS20095 Protein ID WP_223358604.1
Coordinates 4124331..4124582 (+) Length 84 a.a.

Genomic Context

IT072_RS20065IT072_RS20080IT072_RS20085IT072_RS20090IT072_RS20095IT072_RS20100IT072_RS20115IT072_RS20120IT072_RS20070IT072_RS20075IT072_RS20105IT072_RS20110IT072_RS20125IT072_RS20130
Location: 4120167..4121064 (898 bp)
Type: Others
Protein ID: Protein_3945
Location: 4122320..4122601 (282 bp)
Type: Others
Protein ID: WP_223358601.1
Location: 4122617..4123435 (819 bp)
Type: Others
Protein ID: WP_223358602.1
Location: 4123437..4124267 (831 bp)
Type: Others
Protein ID: WP_223358603.1
Location: 4124331..4124582 (252 bp)
Type: Antitoxin
Protein ID: WP_223358604.1
Location: 4124579..4124839 (261 bp)
Type: Toxin
Protein ID: WP_223358605.1
Location: 4126467..4126907 (441 bp)
Type: Others
Protein ID: WP_223358608.1
Location: 4127204..4128526 (1323 bp)
Type: Others
Protein ID: WP_223358609.1
Location: 4121084..4121458 (375 bp)
Type: Others
Protein ID: WP_223358599.1
Location: 4121638..4122048 (411 bp)
Type: Others
Protein ID: WP_223358600.1
Location: 4124864..4125613 (750 bp)
Type: Others
Protein ID: WP_223358606.1
Location: 4125623..4126417 (795 bp)
Type: Others
Protein ID: WP_223358607.1
Location: 4128721..4129113 (393 bp)
Type: Others
Protein ID: WP_223358610.1
Location: 4129110..4129382 (273 bp)
Type: Others
Protein ID: WP_223358611.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
IT072_RS20065 (IT072_19965)4120167..4121064+898Protein_3945IS5 family transposase-
IT072_RS20070 (IT072_19970)4121084..4121458-375WP_223358599.1EXLDI protein-
IT072_RS20075 (IT072_19975)4121638..4122048-411WP_223358600.1DUF1214 domain-containing protein-
IT072_RS20080 (IT072_19980)4122320..4122601+282WP_223358601.1flagellar FlbD family protein-
IT072_RS20085 (IT072_19985)4122617..4123435+819WP_223358602.1MotA/TolQ/ExbB proton channel family protein-
IT072_RS20090 (IT072_19990)4123437..4124267+831WP_223358603.1flagellar motor protein MotB-
IT072_RS20095 (IT072_19995)4124331..4124582+252WP_223358604.1type II toxin-antitoxin system prevent-host-death family antitoxinAntitoxin
IT072_RS20100 (IT072_20000)4124579..4124839+261WP_223358605.1Txe/YoeB family addiction module toxinToxin
IT072_RS20105 (IT072_20005)4124864..4125613-750WP_223358606.1ABC transporter permease-
IT072_RS20110 (IT072_20010)4125623..4126417-795WP_223358607.1AraC family transcriptional regulator-
IT072_RS20115 (IT072_20015)4126467..4126907+441WP_223358608.1DUF2000 family protein-
IT072_RS20120 (IT072_20020)4127204..4128526+1323WP_223358609.1sodium:proton exchanger-
IT072_RS20125 (IT072_20025)4128721..4129113-393WP_223358610.1PIN domain-containing protein-
IT072_RS20130 (IT072_20030)4129110..4129382-273WP_223358611.1type II toxin-antitoxin system prevent-host-death family antitoxin-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-71)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10316.81 Da        Isoelectric Point: 9.4417

>T182018 WP_223358605.1 NZ_CP065037:4124579-4124839 [Leifsonia sp. ZF2019]
MKLIWDQNAWEDYLYWQAQDRRVVKRINQLLVDILRNGNTGIGKPEALKHGFQGFWSRRITDEHRLVYKVTEDAVLIAQC
RYHYAP

Download         Length: 261 bp

>T182018 NZ_CP086259:4776830-4777207 [Escherichia coli]
ATGAATACATTACCCGACACTCACGTACGGGAGGCATCGGGCTGCCCGTCTCCCATCACCATCTGGCAGACACTGCTCAC
CCGACTGCTGGACCAGCACTATGGCCTCACGCTGAATGACACACCGTTCGCTGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGAATTTCACTGTGTGACGCGGTGAACTTTCTCGTTGAAAAATACGCGCTGGTACGTACCGACCAGCCGGGATTC
AGCGCAGGAGCCCCGTCGCAGTTAATCAACAGCATTGATATTCTCCGGGCACGCCGGGCAACCGGCCTGATGACCCGCGA
TAACTACAGAACGGTAAATAACATTACCCGGGGGAAGCATCCGGAAGCGAAACAATGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9362.47 Da        Isoelectric Point: 4.3423

>AT182018 WP_223358604.1 NZ_CP065037:4124331-4124582 [Leifsonia sp. ZF2019]
MKTLSYSESRAHYAATLDAVLDDREEVVITRAGREPVVMVALEDYESLKETAYLLRSPANARRLIESIERLDDGEGTPHD
LLE

Download         Length: 252 bp

>AT182018 NZ_CP086259:4776406-4776783 [Escherichia coli]
GTGTCAGACACACTCCCCGGGACAACGCCTCCCGACGACAATCACGACCGCCCCTGGTGGGGGCTGCCCTGCACCGTGAC
GCCCTGTTTCGGGGCCCGACTGGTACAGGAGGGTAACCGCCTGCATTACCTTGCAGACCGCGCCGGTATCAGAGGCAGGT
TCAGCGACGTAGATGCGTACCACCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCGGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTCACACTGTATGCGAAAGGGCTGACCTGCGAAGCCGACACCCTCGGCTCCTG
TGGTTACGTTTATCTGGCTGTTTATCCGACACCGGCAGCGCCCGCAACCACCGTATAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References