Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DinJ-YafQ (relBE)/YafQ-RelB
Location 1495799..1496341 Replicon chromosome
Accession NZ_CP065030
Organism Pectobacterium versatile strain F131

Toxin (Protein)


Gene name yafQ Uniprot ID -
Locus tag F131LOC_RS06705 Protein ID WP_103972206.1
Coordinates 1496063..1496341 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID -
Locus tag F131LOC_RS06700 Protein ID WP_103972205.1
Coordinates 1495799..1496059 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F131LOC_RS06675 1491085..1492094 + 1010 Protein_1293 NAD-dependent epimerase -
F131LOC_RS06680 1492151..1493314 + 1164 Protein_1294 nucleotide sugar dehydrogenase -
F131LOC_RS06685 1493360..1494211 - 852 WP_103972203.1 dTDP-4-dehydrorhamnose reductase -
F131LOC_RS06690 1494208..1494744 - 537 WP_103972204.1 dTDP-4-dehydrorhamnose 3,5-epimerase -
F131LOC_RS06695 1494746..1495615 - 870 WP_103972228.1 glucose-1-phosphate thymidylyltransferase RfbA -
F131LOC_RS06700 1495799..1496059 + 261 WP_103972205.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
F131LOC_RS06705 1496063..1496341 + 279 WP_103972206.1 type II toxin-antitoxin system YafQ family toxin Toxin
F131LOC_RS06710 1496574..1497470 + 897 WP_039482588.1 UTP--glucose-1-phosphate uridylyltransferase -
F131LOC_RS06715 1497526..1497726 - 201 WP_103972229.1 hypothetical protein -
F131LOC_RS06720 1497867..1498484 - 618 WP_103972207.1 plasmid pRiA4b ORF-3 family protein -
F131LOC_RS06725 1498731..1500137 + 1407 WP_039492568.1 NADP-dependent phosphogluconate dehydrogenase -
F131LOC_RS06730 1500604..1500897 + 294 WP_010296810.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - wza / ugd / wbtL / galF / gnd 1459966..1585748 125782


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(4-92)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-84)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 11156.81 Da        Isoelectric Point: 10.0684

>T181945 WP_103972206.1 NZ_CP065030:1496063-1496341 [Pectobacterium versatile]
MKKQREIAYSGQFQRDVKKAQRRHKNMNKLKTLMQLLLEDKRPLPQEYQDHPLQGNYKGYRDAHIEPDWLLIYKLTDDVL
RFERTGTHADLF

Download         Length: 279 bp

>T181945 NZ_CP086220:c1011640-1011533 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGGATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9282.72 Da        Isoelectric Point: 5.6706

>AT181945 WP_103972205.1 NZ_CP065030:1495799-1496059 [Pectobacterium versatile]
MAANAFVRARIDENLKNEAAEVLASMGLTVSDLVRITLTKVAKEKALPFDMHVPNKLTAQTMADSEKGVDVHTAKDAADL
FDKLGI

Download         Length: 261 bp

>AT181945 NZ_CP086220:1011688-1011755 [Escherichia coli]
GTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTAAACCTCTCAACGTGCGGGGGTTTTCTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References