Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 273579..274104 Replicon plasmid pBS3c
Accession NZ_CP064934
Organism Rhizobium phaseoli strain BS3

Toxin (Protein)


Gene name yoeB Uniprot ID B3Q138
Locus tag HER27_RS26870 Protein ID WP_010025739.1
Coordinates 273579..273851 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A192TIM2
Locus tag HER27_RS26875 Protein ID WP_010025738.1
Coordinates 273853..274104 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HER27_RS26850 269166..271097 + 1932 WP_064826146.1 cyclase -
HER27_RS26855 271208..271693 - 486 WP_141397925.1 hypothetical protein -
HER27_RS26860 271764..272243 - 480 WP_010024037.1 class I SAM-dependent methyltransferase -
HER27_RS26865 272366..273541 + 1176 WP_012490438.1 DUF3095 domain-containing protein -
HER27_RS26870 273579..273851 - 273 WP_010025739.1 Txe/YoeB family addiction module toxin Toxin
HER27_RS26875 273853..274104 - 252 WP_010025738.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
HER27_RS26880 274184..275521 - 1338 WP_010025737.1 nucleotide sugar dehydrogenase -
HER27_RS26885 276023..277366 + 1344 WP_064826145.1 adenylate/guanylate cyclase domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..413456 413456


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10743.42 Da        Isoelectric Point: 9.4530

>T181899 WP_010025739.1 NZ_CP064934:c273851-273579 [Rhizobium phaseoli]
MKLLWTPTSWEEYQYWQKTDQKMVEKINELLKDTKRSPFKGLGKPEPLKGDLSGLWSRRILGEHRLVYCVTGKGSDQQLE
IIQCRFHYEK

Download         Length: 273 bp

>T181899 NZ_CP086200:c2668763-2668482 [Xanthomonas oryzae pv. oryzae]
GTGATCAGGAGCTTTATCGACAAGGACGCCGAAAAGATCTGGCTGGGTGAGCGTTCCCGCCGGTTGCCTGCCGACATCCA
ATTGGTCGCGCGCCGCAAGTTGCGCATGCTCAATGCCGCCGCACATCTCGACGATCTGCGGATCCCGCCCGCCAACCGGC
TGGAAGCGTTGAAGGGCCAGCGGCGCGGCCAGTACAGCATCCGGATCAACGATCAATGGCGCATCTGCTTCCGATGGATG
GAAGGCGATGTGGTCCAGGTCGAAATCGTCGATTACCACTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9345.63 Da        Isoelectric Point: 5.6513

>AT181899 WP_010025738.1 NZ_CP064934:c274104-273853 [Rhizobium phaseoli]
MAHVRLTEFRQNIATYFDQVLSSRAPLLVTRQGSEAMVLIAESEYESMQETLHLLSTPANSARLRESIAQLRKGQVIESD
PTL

Download         Length: 252 bp

>AT181899 NZ_CP086200:c2668464-2668174 [Xanthomonas oryzae pv. oryzae]
ATGACGGTCCTACCCAATATCCATCCTGGCGACATTCTGCTTGAGGAGTTTCTCGAGCCTCTGGGCATCAGCCAGAATGC
ACTGGCACGCGCCACCGGCGTCCCGCCGCGCCGTATCAACGAAATCGTGCTGGGCAAGCGCGGCATCACTGCCGACACTG
CCGTGCGTCTGGCCGCCGCGTTGGGCACCTCCGAGCGCTTCTGGCTGGGCCTGCAGGCCGACTACGAGCTGGAACAGGCG
CATCGCGCGCTGGGCGATTTGCCGGCACGGATCAAGCGGCTGGCGGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A192TIV7

Antitoxin

Source ID Structure
AlphaFold DB A0A192TIM2

References