Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 1510262..1510975 Replicon chromosome
Accession NZ_CP064872
Organism Pantoea sp. SM3640

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag IV493_RS06855 Protein ID WP_195857964.1
Coordinates 1510661..1510975 (-) Length 105 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag IV493_RS06850 Protein ID WP_033783335.1
Coordinates 1510262..1510594 (-) Length 111 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IV493_RS06830 1505638..1506279 + 642 WP_013358224.1 protein phosphatase CheZ -
IV493_RS06835 1506468..1507619 + 1152 WP_013358223.1 flagellar type III secretion system protein FlhB -
IV493_RS06840 1507612..1509711 + 2100 WP_195857962.1 flagellar biosynthesis protein FlhA -
IV493_RS06845 1509711..1510103 + 393 WP_195857963.1 flagellar protein FlhE -
IV493_RS06850 1510262..1510594 - 333 WP_033783335.1 HigA family addiction module antidote protein Antitoxin
IV493_RS06855 1510661..1510975 - 315 WP_195857964.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IV493_RS06860 1511050..1512048 - 999 WP_147789041.1 aldo/keto reductase -
IV493_RS06865 1512173..1513120 - 948 WP_195857965.1 LysR family transcriptional regulator -
IV493_RS06870 1513211..1514941 - 1731 WP_033732941.1 arginine--tRNA ligase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(7-100)

Antitoxin

Toxin-antitoxin system, antidote protein, HigA

(1-99)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 12186.85 Da        Isoelectric Point: 9.5041

>T181863 WP_195857964.1 NZ_CP064872:c1510975-1510661 [Pantoea sp. SM3640]
VATLRNIESFRDDWLENYFLYGKYSKRIPSTLSSSLARKLDIINAAISFKDLRSPPGNRYEELNPPLEGYASIRVNEQYR
LIFKWIEGKAVDLYLDAHSYKTHK

Download         Length: 315 bp

>T181863 NZ_CP086193:c1138123-1137200 [Xanthomonas oryzae]
ATGAACGAACCTGACAAGAGCAGGCGCACTGTTGCCGCGTCGGTTCGCGCCCGGCTGCTCAACAAGGCCCGCGCCGAAAG
ACTCGACTTCAACCTGCTGCTGACCCGCTACGCGCTGGAGCGCGTCCTTTACCGCCTGAGCGTTTCGGAGCAGCAGGGTC
AATTCTTGCTCAAAGGTGCGCTGCTGTTCGACATCTGGTTCGACATACCGCATCGCCCGACGCACGATGCCGACCTGCTG
GGCTTCGGCTCCACCGAGATCCCACATCTGGAAGACCTGTTCCGCAGAATCAGTCAAATCGCCAGCGATGACGGCATCGT
GTTTCAGGCCGACAGCGTGAAGGCCGCCGAAATCCGCAAGGAGGCCAACTACGCGGGCGTCCGTGTGACGATGATCGGCC
TGCTCGATGGCGCGCGCTGCACGGTGCAGATCGACATCGGTTTCGGCGACGCCGTGACGCCCGGCCCGGACAACGTGCAG
TACCCAGTCATCCTCGACGGCATGCCGCAGCCGCAACTGCGGGTCTATCCCCGCTACACCGTGGTCGCCGAAAAGCTGGA
AGCGATGGTCAAGCTCGGCATCCTCAACAGCCGGATGAAGGACTACTTCGACCTCTGGGTTCTCGCCGGACATTCCGACT
TCGACGGTGCGGTGCTGGCCACGGCCATTCGCGCCACGTTCGAGTGCAGGGGTACGGCCATCCCACCCGGCGCGCCGCTG
GGCCTCACCGATGAGTTCGGCCTGGACGAGCAGAAGACAAAGCAGTGGCAGGCGTTCCTGCGCAAGAACACCTTGGAGCC
GATGCCGCTGACCACGGTGATCGAAGCGCTGCGCGAATTCGTGCTGCCCGTGCTGGCCGCGCTCGCGGCAGGCGAAGGTT
TCGACCGCCAGTGGCGCGCGGGCGCGGGATGGGATGCGGCCTGA

Antitoxin


Download         Length: 111 a.a.        Molecular weight: 12559.38 Da        Isoelectric Point: 5.1358

>AT181863 WP_033783335.1 NZ_CP064872:c1510594-1510262 [Pantoea sp. SM3640]
MNQATRKPTTVGDVLLYEYLEPTGLKILDLAEMLKVHRNTVSALVNNNRKLTPDMAFRLAAAFDTSVEFWLNLQNSVDIW
EVMHDARAQEEISRVTPLKDFLAQKENQVA

Download         Length: 333 bp

>AT181863 NZ_CP086193:c1138719-1138120 [Xanthomonas oryzae]
ATGGACACGACCGTCGACAAGCTGCTGGAGCTGGTGCGCACGCGGGGACTTCTGCGCCCGCACGATCTGGCCCCACTGGG
CATCCCACGGGTGGCCCTGACGCGGGCCGTTCGGCGCGGGCAACTGGAGCGCGTCGGGCGCGGCCTGTACGGCCTGGTGG
CGCGTCCGGTGTCGGCCCACGGCACGCTGGCCGAAGTCGCGCGCCGCGTGCCCAAGGGCGTGGTCTGCCTGCTGTCGGCG
CTGCGCGTCCACGACCTGACGACCCAGGCCCCGTTCGAGGTGTGGCTGGCCATCGACAACAAGGCCGCTGCCCCGAAGCT
GGACTACCCGCCGCTACGTCTCGTGCGCTTCTCCGGGCCGGCGCTGAGCGAGGGCGTCGAGGAACACGTTGTTGATGGTG
TGCCCGTCCACGTGACCAGCGTCGCCAAGACCGTGGCCGACTGCTTCAAGTACCGCAACAAGATCGGCATCGACGTGGCG
CTGGAAGCGCTGCGCGAGGCGTGGGTTGCCCGGCGCATGACCAGCGACGAGATCTGGCACTACGCCAAGATCGACCGCGT
CGCCAACGTGATGCGTCCCTATCTGGAGAGCCTGGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References