Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 1325003..1325663 Replicon chromosome
Accession NZ_CP064872
Organism Pantoea sp. SM3640

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag IV493_RS05985 Protein ID WP_195857904.1
Coordinates 1325003..1325356 (+) Length 118 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag IV493_RS05990 Protein ID WP_013358385.1
Coordinates 1325361..1325663 (+) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IV493_RS05960 1320554..1321099 - 546 WP_195857899.1 GNAT family N-acetyltransferase -
IV493_RS05965 1321356..1322426 + 1071 WP_195857900.1 iron-containing alcohol dehydrogenase family protein -
IV493_RS05970 1322472..1323773 + 1302 WP_195857901.1 LLM class flavin-dependent oxidoreductase -
IV493_RS05975 1323963..1324244 + 282 WP_195857902.1 hypothetical protein -
IV493_RS05980 1324342..1324743 + 402 WP_195857903.1 tolA family protein -
IV493_RS05985 1325003..1325356 + 354 WP_195857904.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IV493_RS05990 1325361..1325663 + 303 WP_013358385.1 XRE family transcriptional regulator Antitoxin
IV493_RS06000 1326333..1327256 + 924 WP_013358384.1 sugar ABC transporter substrate-binding protein -
IV493_RS06005 1327289..1328773 + 1485 WP_013358383.1 sugar ABC transporter ATP-binding protein -
IV493_RS06010 1328797..1329822 + 1026 WP_179291192.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-106)

Antitoxin

Cro/C1-type helix-turn-helix domain

(33-79)


Sequences

Toxin        


Download         Length: 118 a.a.        Molecular weight: 13620.70 Da        Isoelectric Point: 10.1378

>T181862 WP_195857904.1 NZ_CP064872:1325003-1325356 [Pantoea sp. SM3640]
VWMIKTTERFDRWFTLLNDSDRACVLAALMVLREKGPGLSRPYADTIKGSAYSNMKELRIQSRGDPIRAFFAFDPNRTAM
VLCAGNKAGNEKRFYREMLPVADREFTHWLKSFNHKE

Download         Length: 354 bp

>T181862 NZ_CP086193:c637858-637607 [Xanthomonas oryzae]
ATGCTACGGCTGCGTGAATTCCTGAGGCCGAAGAATCCCGATGCCGCGAGGCGGGCCGGCGAAGCGATTAGGCGCGGCGT
CCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAGAAGATCTGTCTGAACAGTATCGGGAGTGGCTTATCGATT
TTGGGGATAGCGGCTATGTGGCTCGGTACCGCTTCGATGGGGATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAA
GCGGGGTACTGA

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 10895.70 Da        Isoelectric Point: 5.7134

>AT181862 WP_013358385.1 NZ_CP064872:1325361-1325663 [Pantoea sp. SM3640]
MGRTLEQLIADEKPEVVADAQAMATEILLNIHLAELREKVQKTQVEMAQALGITQPTVAGMEKPGRDLKLSTLKRYVDAA
GGKLRLVVELPDGSHFGFVV

Download         Length: 303 bp

>AT181862 NZ_CP086193:c638163-637885 [Xanthomonas oryzae]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCAGAGTCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGCGAGGCGCTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACTGGCCTGCATGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCTAGCTGGGGA
ACTGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References