Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 4648834..4649423 Replicon chromosome
Accession NZ_CP064871
Organism Xanthomonas oryzae pv. oryzicola strain YN01

Toxin (Protein)


Gene name graT Uniprot ID A0A0C5V8F2
Locus tag IYN96_RS21090 Protein ID WP_024712137.1
Coordinates 4648834..4649115 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag IYN96_RS21095 Protein ID WP_011260746.1
Coordinates 4649133..4649423 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IYN96_RS21085 (IYN96_20975) 4646478..4648739 + 2262 WP_240113057.1 exodeoxyribonuclease V subunit alpha -
IYN96_RS21090 (IYN96_20980) 4648834..4649115 + 282 WP_024712137.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IYN96_RS21095 (IYN96_20985) 4649133..4649423 + 291 WP_011260746.1 HigA family addiction module antitoxin Antitoxin
IYN96_RS21100 (IYN96_20990) 4650336..4651730 + 1395 WP_024712138.1 type III secretion system effector XopQ -
IYN96_RS21105 4651833..4652020 - 188 Protein_4006 hypothetical protein -
IYN96_RS21110 (IYN96_20995) 4652181..4652513 - 333 WP_011260743.1 hypothetical protein -
IYN96_RS21115 (IYN96_21000) 4652768..4653073 + 306 WP_224229802.1 hypothetical protein -
IYN96_RS21120 (IYN96_21005) 4653223..4653645 + 423 WP_044751863.1 PAAR domain-containing protein -
IYN96_RS21125 (IYN96_21010) 4653648..4654124 + 477 WP_047339412.1 DUF4123 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(4-93)

Antitoxin

Cro/C1-type helix-turn-helix domain

(14-68)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 11125.91 Da        Isoelectric Point: 10.5318

>T181859 WP_024712137.1 NZ_CP064871:4648834-4649115 [Xanthomonas oryzae pv. oryzicola]
MIRSFIDKDAEKIWLGERSRRLPADIQLVARRKLRMLNAAAHLDDLRIPPANRLEALKGQRRGQYNIRINDQWRICFRWM
EGDVVQVEIVDYH

Download         Length: 282 bp

>T181859 NZ_CP086191:2094451-2094585 [Xanthomonas oryzae]
ATGAAGCGTGCAATTGTGCTGCTCGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10420.07 Da        Isoelectric Point: 7.2040

>AT181859 WP_011260746.1 NZ_CP064871:4649133-4649423 [Xanthomonas oryzae pv. oryzicola]
MTVLPNIHPGDILLEEFLEPLGISQNALARATGVPPRRINEIVLGKRGITADTAVRLAAALGTSERFWLGLQADYELEQA
HRALGDLPARIKRLAA

Download         Length: 291 bp

>AT181859 NZ_CP086191:2094235-2094387 [Xanthomonas oryzae]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5V8F2

Antitoxin

Source ID Structure

References