Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 2729471..2730924 Replicon chromosome
Accession NZ_CP064871
Organism Xanthomonas oryzae pv. oryzicola strain YN01

Toxin (Protein)


Gene name rlegT Uniprot ID A0A5C2EYQ5
Locus tag IYN96_RS12380 Protein ID WP_047339759.1
Coordinates 2729471..2730322 (-) Length 284 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID A0A0C5V250
Locus tag IYN96_RS12385 Protein ID WP_024710981.1
Coordinates 2730319..2730924 (-) Length 202 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IYN96_RS12355 (IYN96_12305) 2724510..2725472 - 963 WP_044751530.1 IS110 family transposase -
IYN96_RS12360 (IYN96_12310) 2725698..2726000 - 303 WP_047339762.1 hypothetical protein -
IYN96_RS12365 (IYN96_12315) 2726873..2727214 - 342 WP_053056036.1 ParB N-terminal domain-containing protein -
IYN96_RS12370 (IYN96_12320) 2727211..2728497 - 1287 WP_228757531.1 recombinase family protein -
IYN96_RS12375 (IYN96_12325) 2728914..2729384 - 471 WP_047339760.1 hypothetical protein -
IYN96_RS12380 (IYN96_12330) 2729471..2730322 - 852 WP_047339759.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
IYN96_RS12385 (IYN96_12335) 2730319..2730924 - 606 WP_024710981.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
IYN96_RS12390 (IYN96_12340) 2731168..2731953 - 786 WP_053056035.1 helix-turn-helix domain-containing protein -
IYN96_RS12395 (IYN96_12345) 2732279..2732455 + 177 WP_014503024.1 hypothetical protein -
IYN96_RS12400 (IYN96_12350) 2732766..2733851 + 1086 WP_047339758.1 sensor domain-containing diguanylate cyclase -
IYN96_RS12405 (IYN96_12355) 2733894..2734403 - 510 WP_014503022.1 chemotaxis protein CheW -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2713709..2739213 25504
flank IS/Tn - - 2724510..2725472 962


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(34-262)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(8-55)


Sequences

Toxin        


Download         Length: 284 a.a.        Molecular weight: 31056.91 Da        Isoelectric Point: 7.0657

>T181858 WP_047339759.1 NZ_CP064871:c2730322-2729471 [Xanthomonas oryzae pv. oryzicola]
MSNVAASVRARLRGVAKAQGVDFNQVLVRFALERILYRLSQSEHADRFLLKGALLFTLWYDMPHRATRDADLLGFGASDL
ESVAQTFRDIASVAVDDGIVFDPASVVAEEIRKDAGYAGARILIGGELAKARCRTQIDVGFGDAVTPAPVHSVYPVLLED
LPAPRLRTYPVYTVIAEKLHAIALLGMTNSRMKDYLDLSVLLERESLDIDLLAQAVKATFERRGMAVPAALPIGMTDEFA
HDTSRQALWQAFLKKNELAPEPLAAIVVRLRAALEPALHRAAR

Download         Length: 852 bp

>T181858 NZ_CP086191:2094235-2094387 [Xanthomonas oryzae]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA

Antitoxin


Download         Length: 202 a.a.        Molecular weight: 22257.92 Da        Isoelectric Point: 9.9253

>AT181858 WP_024710981.1 NZ_CP064871:c2730924-2730319 [Xanthomonas oryzae pv. oryzicola]
MLSDTHTQRVLDLASQKGLLRASDLDAINAPRVVLTRLTAAGVLERVGRGLYRLPDAQGSEFESLAAIATKVPQAVFCLL
TALQFHELTTQLPRQIWIAMPRGSHAPRIGYPPVKMVQMTGDVYAAGIEEHLRDGVRLRVYGAAKTVVDCFKHRNKIGLD
VALEALKDVRAKRKATADDLWRFATVCRVANVMRPYLEAVE

Download         Length: 606 bp

>AT181858 NZ_CP086191:2094451-2094585 [Xanthomonas oryzae]
ATGAAGCGTGCAATTGTGCTGCTCGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A5C2EYQ5

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V250

References