Detailed information of TA system TA181850

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yefM-yoeB (relBE)/Txe-RelB
• Location: 1325418..1325947
• Replicon: chromosome
• Accession: NZ_CP064860
• Organism: Companilactobacillus futsaii strain CQ16Z11

Toxin (Protein)

• Gene name: yoeB
• Uniprot ID: -
• Locus tag: ITJ83_RS06380
• Protein ID: WP_195701102.1
• Coordinates: 1325684..1325947 (+)
• Length: 88 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: ITJ83_RS06375
• Protein ID: WP_162256560.1
• Coordinates: 1325418..1325681 (+)
• Length: 88 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ITJ83_RS06360	1320418..1321803	-	1386	WP_195702065.1	group II intron reverse transcriptase/maturase	-
ITJ83_RS06365	1322235..1323966	+	1732	Protein_1239	phosphoenolpyruvate synthase	-
ITJ83_RS06370	1324016..1325278	-	1263	WP_195701101.1	replication-associated recombination protein A	-
ITJ83_RS06375	1325418..1325681	+	264	WP_162256560.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
ITJ83_RS06380	1325684..1325947	+	264	WP_195701102.1	Txe/YoeB family addiction module toxin	Toxin
ITJ83_RS06385	1326372..1327403	+	1032	WP_149029777.1	IS30 family transposase	-
ITJ83_RS06390	1327912..1328178	+	267	WP_195701103.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	-
ITJ83_RS06395	1328171..1328533	+	363	WP_195701104.1	type II toxin-antitoxin system PemK/MazF family toxin	-
ITJ83_RS06400	1328825..1329638	+	814	Protein_1246	EamA family transporter	-
ITJ83_RS06405	1329695..1329958	-	264	WP_057814812.1	Txe/YoeB family addiction module toxin	-
ITJ83_RS06410	1329948..1330229	-	282	WP_057814815.1	type II toxin-antitoxin system prevent-host-death family antitoxin	-
ITJ83_RS06415	1330655..1330897	+	243	WP_057814817.1	ATP-binding cassette domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Integrative and Conjugative Element	-	-	1318188..1500689	182501

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (20-86)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (6-58)

Sequences

Toxin

Protein

• Length: 88 a.a.
• Molecular weight: 10471.00 Da
• Isoelectric Point: 9.7755

>T181850 WP_195701102.1 NZ_CP064860:1325684-1325947 [Companilactobacillus futsaii]
MSYSIKFKNSSKNDLKKIKNSPFCKKFDEIIKKLSVNPYDPSDNFEKLFPPEDKLYSRRLNIQHRIVYSIDEEKQIVHIY
SAWNHYA

Nucleotide

• Length: 264 bp

>T181850 NZ_CP086188:c974455-974174 [Xanthomonas oryzae]
GTGATCAGGAGCTTTATCGACAAGGACGCCGAAAAGATCTGGCTGGGTGAGCGTTCCCGCCGGTTGCCTGCCGACATCCA
ATTGGTCGCGCGCCGCAAGTTGCGCATGCTCAATGCCGCCGCGCATCTCGACGATCTGCGGATCCCGCCCGCCAACCGGC
TGGAAGCGTTGAAGGGCCAGCAGCGCGGCCAGTACAGCATCCGGATCAACGATCAATGGCGCATCTGCTTCCGATGGATG
GAAGGCGATGTGGTCCAGGTCGAAATCGTCGATTACCACTGA

Antitoxin

Protein

• Length: 88 a.a.
• Molecular weight: 9867.98 Da
• Isoelectric Point: 4.5895

>AT181850 WP_162256560.1 NZ_CP064860:1325418-1325681 [Companilactobacillus futsaii]
MQRMTNPTQARKDFYKIIKSVNENSTPIEINGRTEDDSAVIMSAKDYRSLQETLYLMNDGTLNKVHKAIADDSGETDITN
GVDWDKI

Nucleotide

• Length: 264 bp

>AT181850 NZ_CP086188:c974156-973866 [Xanthomonas oryzae]
ATGACGGTCCTACCCAATATCCATCCTGGCGACATTCTGCTTGAGGAGTTTCTCGAGCCTCTGGGCATCAGCCAGAACGC
ACTGGCACGCGCCACCGGCGTCCCGCCGCGCCGTATCAACGAAATCGTGCTGGGCAAGCGCGGCATCACTGCCGACACTG
CCGTGCGTCTGGCCGCCGCGTTGGGCACCTCCGAGCGCTTCTGGCTGGGCCTGCAGGCCGACTACGAGCTGGAACAGGCG
CATCGCGCGCTGGGCGATTTGCCGGCACGGATCAAGCGGCTGGCGGCGTGA