Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) yonT-SR6/-
Location 65736..65953 Replicon plasmid p_unnamed
Accession NZ_CP064819
Organism Bacillus subtilis strain SH1

Toxin (Protein)


Gene name yonT Uniprot ID -
Locus tag ITP52_RS21840 Protein ID WP_109962752.1
Coordinates 65736..65912 (-) Length 59 a.a.

Antitoxin (RNA)


Gene name SR6
Locus tag -
Coordinates 65853..65953 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ITP52_RS21795 60847..61182 - 336 WP_109962744.1 hypothetical protein -
ITP52_RS21800 61220..61516 - 297 WP_109962745.1 hypothetical protein -
ITP52_RS21805 61592..61837 - 246 WP_109962746.1 hypothetical protein -
ITP52_RS21810 61837..62037 - 201 WP_109962747.1 hypothetical protein -
ITP52_RS21815 62075..62974 - 900 WP_109962748.1 hypothetical protein -
ITP52_RS21820 63086..63517 - 432 WP_109962749.1 hypothetical protein -
ITP52_RS21825 63934..65151 - 1218 WP_109962750.1 hypothetical protein -
ITP52_RS21830 65233..65421 - 189 WP_003230987.1 hypothetical protein -
ITP52_RS21835 65466..65717 - 252 WP_109962751.1 hypothetical protein -
ITP52_RS21840 65736..65912 - 177 WP_109962752.1 hypothetical protein Toxin
- 65853..65953 + 101 NuclAT_0 - Antitoxin
- 65853..65953 + 101 NuclAT_0 - Antitoxin
- 65853..65953 + 101 NuclAT_0 - Antitoxin
- 65853..65953 + 101 NuclAT_0 - Antitoxin
ITP52_RS21845 66944..67138 + 195 WP_004399291.1 hypothetical protein -
ITP52_RS21850 67178..69685 + 2508 WP_109962753.1 hypothetical protein -
ITP52_RS21855 69949..70224 + 276 WP_072692660.1 HU family DNA-binding protein -
ITP52_RS21860 70647..70761 + 115 Protein_113 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..118493 118493


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 59 a.a.        Molecular weight: 6859.40 Da        Isoelectric Point: 12.8196

>T181752 WP_109962752.1 NZ_CP064819:c65912-65736 [Bacillus subtilis]
VLEKVGIIVAFLISLTVLTINSLTIVEKIRNLKNGTSKKKKRIRKRLRPKRQRQHIRR

Download         Length: 177 bp

>T181752 NZ_CP086122:1589030-1589899 [Pseudomonas aeruginosa]
ATGAACATGGCGCAGACCCACACCCCCGTCCCGAACCTGCAACAGCGCTTTCCCGAGCGGCTGGTGCAACTGGCCGACGG
CGCCCAGCTGGCCATCCGCGAATGCGGCCAGGGCCCGGTGGTGGTGCTGTTGCACGGCATCGGTTCGGGCTCGGCGTCCT
GGCTGCATTGCGCCCAGCGCCTGGCCGCCGGCAATCGGGTGATCGCCTGGGACGCGCCGGGTTACGGCCTGTCCACGCCG
CTGCCGCCGGCCCGGCCCAAGGCCTGCGACTACGCCGCGTGCCTGGAGCTGCTGCTGGATGCGCTGGGCGTGGAGAGCTG
CCTGCTGGTGGGCCACTCCCTCGGCGCGCTGATGGCCACGGCCTACGCCGCCGGCATCGGCGCGGCGCGGGTGCGCCGCC
TGGTGCTGCTCAGCCCGGCGCGCGGCTACGGCGCCGCCGAGCTGCGCGACAGCGGCGCCCAGGTGCGCCGCCAGCGCCTG
GAGAACCTGGAGCGCTTCGGTATCGACGGCATGGCCAGCGAGCGCACCGCGCGCCTGCTCGGCCGCAACCCCAGCGAGGA
GGCCCTGGCCTGGGTGCGCTGGAACATGGCGCGGCTCAACCCCGAGGGCTACCGCCAGGCCGTCGAGCTGCTCTGCGGCG
ACGACCTGCTGGGCAACGGGCAGCCTGCCGCTCCTTGCGAGGTGCATTGCGGCGAGGACGACGGCATCACCACGCCCGAG
AGTTGCGGCGCCATCGCCCGCCAGCTCGGCGCGTCGTTCTCGTCGATTCCCGGGGCCGGCCACGCCAGCCCGATCGAACA
ACCCGAAGTGGTCGCAGGACGCATCGGCCACGCGCAACGCCTCTCTCTTGAAGGAACCGCCAATGGATAA

Antitoxin


Download         Length: 101 bp

>AT181752 NZ_CP064819:65853-65953 [Bacillus subtilis]
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTATAATACCCACTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References