Detailed information of TA system TA181749

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): yonT-SR6/-
• Location: 65695..65912
• Replicon: plasmid p_unnamed
• Accession: NZ_CP064819
• Organism: Bacillus subtilis strain SH1

Toxin (Protein)

• Gene name: yonT
• Uniprot ID: -
• Locus tag: ITP52_RS21840
• Protein ID: WP_109962752.1
• Coordinates: 65736..65912 (-)
• Length: 59 a.a.

Antitoxin (RNA)

Gene name	SR6
Locus tag	-
Coordinates	65695..65795 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ITP52_RS21795	60847..61182	-	336	WP_109962744.1	hypothetical protein	-
ITP52_RS21800	61220..61516	-	297	WP_109962745.1	hypothetical protein	-
ITP52_RS21805	61592..61837	-	246	WP_109962746.1	hypothetical protein	-
ITP52_RS21810	61837..62037	-	201	WP_109962747.1	hypothetical protein	-
ITP52_RS21815	62075..62974	-	900	WP_109962748.1	hypothetical protein	-
ITP52_RS21820	63086..63517	-	432	WP_109962749.1	hypothetical protein	-
ITP52_RS21825	63934..65151	-	1218	WP_109962750.1	hypothetical protein	-
ITP52_RS21830	65233..65421	-	189	WP_003230987.1	hypothetical protein	-
ITP52_RS21835	65466..65717	-	252	WP_109962751.1	hypothetical protein	-
-	65695..65795	+	101	-	-	Antitoxin
ITP52_RS21840	65736..65912	-	177	WP_109962752.1	hypothetical protein	Toxin
-	65853..65953	+	101	NuclAT_0	-	-
-	65853..65953	+	101	NuclAT_0	-	-
-	65853..65953	+	101	NuclAT_0	-	-
-	65853..65953	+	101	NuclAT_0	-	-
ITP52_RS21845	66944..67138	+	195	WP_004399291.1	hypothetical protein	-
ITP52_RS21850	67178..69685	+	2508	WP_109962753.1	hypothetical protein	-
ITP52_RS21855	69949..70224	+	276	WP_072692660.1	HU family DNA-binding protein	-
ITP52_RS21860	70647..70761	+	115	Protein_113	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..118493	118493

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 59 a.a.
• Molecular weight: 6859.40 Da
• Isoelectric Point: 12.8196

>T181749 WP_109962752.1 NZ_CP064819:c65912-65736 [Bacillus subtilis]
VLEKVGIIVAFLISLTVLTINSLTIVEKIRNLKNGTSKKKKRIRKRLRPKRQRQHIRR

Nucleotide

• Length: 177 bp

>T181749 NZ_CP086119:5179380-5179634 [Streptomyces huasconensis]
GTGAGGCTTGTGTTCGAGGACCAGGGCTGGGAGGACTACACATCCTGGCTCAAGGACGACCGCAAGATGCTCGCTCGGAT
CAACAAGCTGATCGAGGACGTCAAGCGTGACCCCTTCACGGGGATCGGCAAGCCCGAGCCGCTCAAGTACCACTTGCCCG
GGGCGTGGTCGCGGCGGATCGACGACGAACACCGCCTCGTCTACCTGGTCACGGACAAGGAGATCGTGATCCTCGCTGCC
CGCTATCACTACTGA

Antitoxin

Nucleotide

• Length: 101 bp

>AT181749 NZ_CP064819:65695-65795 [Bacillus subtilis]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATATGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Structures

Antitoxin