Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 2061100..2062553 Replicon chromosome
Accession NZ_CP064794
Organism Xanthomonas oryzae pv. oryzicola strain HGA4

Toxin (Protein)


Gene name rlegT Uniprot ID A0A5C2EYQ5
Locus tag IZG20_RS09525 Protein ID WP_047339759.1
Coordinates 2061100..2061951 (-) Length 284 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID G7TCM4
Locus tag IZG20_RS09530 Protein ID WP_014503027.1
Coordinates 2061948..2062553 (-) Length 202 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IZG20_RS09495 2056141..2057103 - 963 WP_048484029.1 IS110 family transposase -
IZG20_RS09500 2057328..2057630 - 303 WP_048483393.1 hypothetical protein -
IZG20_RS09505 2058503..2058844 - 342 WP_082350382.1 ParB N-terminal domain-containing protein -
IZG20_RS09510 2058841..2059863 - 1023 WP_229690081.1 recombinase family protein -
IZG20_RS09515 2059857..2060126 - 270 WP_229690082.1 hypothetical protein -
IZG20_RS09520 2060543..2061013 - 471 WP_048484031.1 hypothetical protein -
IZG20_RS09525 2061100..2061951 - 852 WP_047339759.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
IZG20_RS09530 2061948..2062553 - 606 WP_014503027.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
IZG20_RS09535 2062797..2063582 - 786 WP_082350383.1 helix-turn-helix domain-containing protein -
IZG20_RS09540 2063908..2064084 + 177 WP_014503024.1 hypothetical protein -
IZG20_RS09545 2064390..2065475 + 1086 WP_014503023.1 sensor domain-containing diguanylate cyclase -
IZG20_RS09550 2065518..2066027 - 510 WP_014503022.1 chemotaxis protein CheW -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
flank IS/Tn - - 2056141..2057103 962


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(34-262)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(8-55)


Sequences

Toxin        


Download         Length: 284 a.a.        Molecular weight: 31056.91 Da        Isoelectric Point: 7.0657

>T181736 WP_047339759.1 NZ_CP064794:c2061951-2061100 [Xanthomonas oryzae pv. oryzicola]
MSNVAASVRARLRGVAKAQGVDFNQVLVRFALERILYRLSQSEHADRFLLKGALLFTLWYDMPHRATRDADLLGFGASDL
ESVAQTFRDIASVAVDDGIVFDPASVVAEEIRKDAGYAGARILIGGELAKARCRTQIDVGFGDAVTPAPVHSVYPVLLED
LPAPRLRTYPVYTVIAEKLHAIALLGMTNSRMKDYLDLSVLLERESLDIDLLAQAVKATFERRGMAVPAALPIGMTDEFA
HDTSRQALWQAFLKKNELAPEPLAAIVVRLRAALEPALHRAAR

Download         Length: 852 bp

>T181736 NZ_CP086118:365061-365336 [Salmonella enterica subsp. enterica serovar Typhimurium]
ATGGGGCAAAGGGAAATTGAATATTCGGGACAGTTCCAGAAAGATGTAAAACGGGCACAAAAGCGTCATAAGGATGTCGG
CAAACTTAAAACACTTATGACGCTTCTGATTCACCACCCTTTTCCCCTTCCTGCCATTTATAAAGATCACCCGTTACAAG
GTTCATATAGCGGATACCGGGATGCCCATATTGAGCCTGACTGGATTCTTATTTATAAGATAACGGATGAATGCCTGCGA
TTTGAACGAACAGGAACGCATGCCGATTTATTTTAA

Antitoxin


Download         Length: 202 a.a.        Molecular weight: 22228.93 Da        Isoelectric Point: 10.0752

>AT181736 WP_014503027.1 NZ_CP064794:c2062553-2061948 [Xanthomonas oryzae pv. oryzicola]
MLSDTHTQRVLDLASQKGLLRASNLDAINAPRVVLTRLTAAGVLERVGRGLYRLPDAQGSEFESLAAIATKVPQAVFCLL
TALQFHELTTQLPRQIWIAMPRGSHAPRIGYPPVKMVQMTGDVYAAGIEEHLRDGVKLRVYGAAKTVVDCFKHRNKIGLD
VALEALKDVRAKRKATADDLWRFATVCRVANVMRPYLEAVE

Download         Length: 606 bp

>AT181736 NZ_CP086118:364798-365058 [Salmonella enterica subsp. enterica serovar Typhimurium]
ATGGCTGCAAATGCGCTTGTTCGTGCCCGTATCGACGAAACGCTGAAGGACCAGGCGGCAGATGTCCTGGCTGAAATGGG
GTTAACCATTTCTGATTTGATACGGATTACACTGACTAAAGTTGCGCGTGAAAAGGCATTGCCTTTTGATTTGCGCATAC
CCAATGAGTTAACGTCCCGAACGATAGAAAATAGCGAAGCTGGCGTTGATATTCATAAAGCCAAAGATGCTGATGATTTG
TTTGACCAGTTAGGGATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A5C2EYQ5

Antitoxin

Source ID Structure
AlphaFold DB G7TCM4

References