Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 4794682..4795271 Replicon chromosome
Accession NZ_CP064780
Organism Xanthomonas oryzae pv. oryzae strain DY89031(J18)

Toxin (Protein)


Gene name graT Uniprot ID A0A8E2YMU3
Locus tag IV492_RS22625 Protein ID WP_011260747.1
Coordinates 4794990..4795271 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag IV492_RS22620 Protein ID WP_133265134.1
Coordinates 4794682..4794972 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IV492_RS22595 4789957..4790433 - 477 WP_011260741.1 DUF4123 domain-containing protein -
IV492_RS22600 4790436..4790858 - 423 WP_033013301.1 PAAR domain-containing protein -
IV492_RS22605 4791008..4791313 - 306 WP_224229802.1 hypothetical protein -
IV492_RS22610 4791568..4791900 + 333 WP_011260743.1 hypothetical protein -
IV492_RS24055 4792060..4792247 + 188 Protein_4322 hypothetical protein -
IV492_RS22615 4792350..4793744 - 1395 WP_011260745.1 type III secretion system effector XopQ -
IV492_RS22620 4794682..4794972 - 291 WP_133265134.1 HigA family addiction module antitoxin Antitoxin
IV492_RS22625 4794990..4795271 - 282 WP_011260747.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IV492_RS22630 4795366..4797624 - 2259 WP_041182333.1 exodeoxyribonuclease V subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(4-93)

Antitoxin

Cro/C1-type helix-turn-helix domain

(14-68)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 11070.83 Da        Isoelectric Point: 10.2139

>T181716 WP_011260747.1 NZ_CP064780:c4795271-4794990 [Xanthomonas oryzae pv. oryzae]
MIRSFIDKDAEKIWLGERSRRLPADIQLVARRKLRMLNAAAHLDDLRIPPANRLEALKGQQRGQYSIRINDQWRICFRWM
EGDVVQVEIVDYH

Download         Length: 282 bp

>T181716 NZ_CP086107:c125163-124828 [Skermanella mucosa]
GTGAGGCGTGGCGATCTGGTCACCATCGCCGCCCGGATCGGCGGCGATTATGACGGCAAACCACGACCCGCAGTGATCAT
CCAGTCCGACGATTTTCCGGAAACCGACAGCGTCACCGTTTCGCTGCTGACCTCCATCGGCATCGACGCCCCACTGCTGA
GACTGCGCATCGACCCGGCGCCGGCCAACAACCTTCGCCAGACCTCCTGGGTCATGATCGACAAGATCGCGACCGTCAGG
CGGAGAAACATAGGGGCCGTCTTCGGCCGTTTGAGCGATGCCGAACTGGTCCAGGTCAACCGCGCCCTGCCGGTGTTTCT
CGGGATCGCAGGCTGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10419.13 Da        Isoelectric Point: 10.0802

>AT181716 WP_133265134.1 NZ_CP064780:c4794972-4794682 [Xanthomonas oryzae pv. oryzae]
MTVLPNIHPGDILLEEFLKPLGISQNALARATGVPPRRINEIVLGKRGITADTAVRLAAALGTSERFWLGLQADYELEQA
HRALGDLPARIKRLAA

Download         Length: 291 bp

>AT181716 NZ_CP086107:c125384-125160 [Skermanella mucosa]
ATGCCTTCAACCGTCCGTCACCGTGTCCAGACCCACCGGGCACAGCTTCGCGCGCAGGGATTGAGGCCGATCCAGATCTG
GGTGCCGGATGTCCGCTCCCCCACGTTCAAGGAAGAGGCGCGGCGGCAGTCCCGGGCAGTCGCCGCCGCACCCGACGAAG
CCGACACCATGGACTTCCTGGAGGATATCCAGGATCTTGGCGATGATGCCGGCGACAGGCCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References