Detailed information of TA system
Overview
TA module
| Type | I | Classification (family/domain) | TMCS/- |
| Location | 2815681..2816260 | Replicon | chromosome |
| Accession | NZ_CP064772 | ||
| Organism | Staphylococcus aureus strain TCH32767 | ||
Toxin (Protein)
| Gene name | MW1434 | Uniprot ID | A0A4P7P609 |
| Locus tag | IXH55_RS13970 | Protein ID | WP_001025401.1 |
| Coordinates | 2815681..2815926 (+) | Length | 82 a.a. |
Antitoxin (RNA)
| Gene name | MW1433 | ||
| Locus tag | - | ||
| Coordinates | 2815895..2816260 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| IXH55_RS13910 (IXH55_13850) | 2811281..2811427 | - | 147 | WP_001795334.1 | hypothetical protein | - |
| IXH55_RS13915 (IXH55_13855) | 2811464..2811646 | - | 183 | WP_000705245.1 | hypothetical protein | - |
| IXH55_RS13920 (IXH55_13860) | 2811717..2811902 | - | 186 | WP_000109189.1 | hypothetical protein | - |
| IXH55_RS13925 (IXH55_13865) | 2811899..2812045 | - | 147 | WP_000345949.1 | hypothetical protein | - |
| IXH55_RS13930 (IXH55_13870) | 2812119..2812973 | - | 855 | WP_001557601.1 | HIRAN domain-containing protein | - |
| IXH55_RS13935 (IXH55_13875) | 2812985..2813701 | - | 717 | WP_001083975.1 | LexA family transcriptional regulator | - |
| IXH55_RS13940 (IXH55_13880) | 2813865..2814107 | + | 243 | WP_000639923.1 | DUF739 family protein | - |
| IXH55_RS13945 (IXH55_13885) | 2814120..2814563 | + | 444 | WP_000435357.1 | hypothetical protein | - |
| IXH55_RS13950 (IXH55_13890) | 2814578..2814727 | + | 150 | WP_000771849.1 | hypothetical protein | - |
| IXH55_RS13955 (IXH55_13895) | 2814768..2814980 | - | 213 | WP_000362644.1 | hypothetical protein | - |
| IXH55_RS13960 (IXH55_13900) | 2815050..2815247 | + | 198 | WP_001148860.1 | hypothetical protein | - |
| IXH55_RS13965 (IXH55_13905) | 2815234..2815614 | - | 381 | WP_000773059.1 | DUF2513 domain-containing protein | - |
| IXH55_RS13970 (IXH55_13910) | 2815681..2815926 | + | 246 | WP_001025401.1 | DUF2829 domain-containing protein | Toxin |
| IXH55_RS13975 (IXH55_13915) | 2815895..2816260 | - | 366 | WP_001128433.1 | hypothetical protein | Antitoxin |
| IXH55_RS13980 (IXH55_13920) | 2816315..2816530 | + | 216 | WP_001097552.1 | hypothetical protein | - |
| IXH55_RS13985 (IXH55_13925) | 2816555..2816818 | + | 264 | WP_001124157.1 | helix-turn-helix domain-containing protein | - |
| IXH55_RS13990 (IXH55_13930) | 2816831..2816992 | + | 162 | WP_001285954.1 | DUF1270 domain-containing protein | - |
| IXH55_RS13995 (IXH55_13935) | 2817071..2817394 | + | 324 | WP_000174998.1 | hypothetical protein | - |
| IXH55_RS14000 (IXH55_13940) | 2817409..2817771 | + | 363 | WP_000985972.1 | hypothetical protein | - |
| IXH55_RS14005 (IXH55_13945) | 2817768..2818934 | + | 1167 | WP_000762530.1 | DUF2800 domain-containing protein | - |
| IXH55_RS14010 (IXH55_13950) | 2818960..2819517 | + | 558 | WP_000645045.1 | DUF2815 family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 2806350..2832062 | 25712 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 82 a.a. Molecular weight: 9468.72 Da Isoelectric Point: 5.7783
>T181709 WP_001025401.1 NZ_CP064772:2815681-2815926 [Staphylococcus aureus]
MNIQEATKIATKNLVSMTRKDWKESHRTKILPTNDSFLQCIISNSDGTNLIRYWQPSADDLMANDWEVINPTRDQELLKQ
F
MNIQEATKIATKNLVSMTRKDWKESHRTKILPTNDSFLQCIISNSDGTNLIRYWQPSADDLMANDWEVINPTRDQELLKQ
F
Download Length: 246 bp
>T181709 NZ_CP086105:494707-495012 [Ralstonia sp. RS650]
ATGACGATGGCCCAACGCACCATCAAGACCCGGCCGTGGGATTCGGCCGAACACCTCCGGACCGAAGCGGACATCGCCGC
CTACCTCGACGCCTGCCTGGAAGAAGCCGGAGATGACCCCGCCTTCATCACGCATGCGCTGGGCGTGGTCGCGCGCTCGC
GCGGCATGACGCAGCTCGCCCGCGAGACCGGGATGACCCGCGAAGGGCTGTACAAGGCGCTTTCCGAGGGCGGCAATCCG
AGCTTTGCGACCGTGCTGAAGGTCATCCGGGCGCTCGGCATCCGGCTGCACGCCGTGCCGACCTGA
ATGACGATGGCCCAACGCACCATCAAGACCCGGCCGTGGGATTCGGCCGAACACCTCCGGACCGAAGCGGACATCGCCGC
CTACCTCGACGCCTGCCTGGAAGAAGCCGGAGATGACCCCGCCTTCATCACGCATGCGCTGGGCGTGGTCGCGCGCTCGC
GCGGCATGACGCAGCTCGCCCGCGAGACCGGGATGACCCGCGAAGGGCTGTACAAGGCGCTTTCCGAGGGCGGCAATCCG
AGCTTTGCGACCGTGCTGAAGGTCATCCGGGCGCTCGGCATCCGGCTGCACGCCGTGCCGACCTGA
Antitoxin
Download Length: 366 bp
>AT181709 NZ_CP064772:c2816260-2815895 [Staphylococcus aureus]
ATGCCCTTGATATCTGATGAATTTGATACACTTACTAAAGACCAACAATATATCTTGTCCGTACTCTACAAAGATTATTT
AGAATGTGTAAAGTTAGGTTCGGTTAAATTAACCTGCAATAATTTTGGAAGTGCTAAAGATATACATACAAAGTATTTTC
AAAAACTACATTTCGAAGATGTAAAATACGATTTAAATAAACTTAAAAACTCTGGGTTCCTAAACGGCGTGTATGCTAGT
AACACTATTTATCATGTAACAATTTCAGACAAGACTGTTGTTTACTTTGAAAATGAGTTTAAAAACAATTTAAAAAGTAT
CATTGATAGCATTTCTAAAATTGCTTCAATAATTCCTGGTCTCTAG
ATGCCCTTGATATCTGATGAATTTGATACACTTACTAAAGACCAACAATATATCTTGTCCGTACTCTACAAAGATTATTT
AGAATGTGTAAAGTTAGGTTCGGTTAAATTAACCTGCAATAATTTTGGAAGTGCTAAAGATATACATACAAAGTATTTTC
AAAAACTACATTTCGAAGATGTAAAATACGATTTAAATAAACTTAAAAACTCTGGGTTCCTAAACGGCGTGTATGCTAGT
AACACTATTTATCATGTAACAATTTCAGACAAGACTGTTGTTTACTTTGAAAATGAGTTTAAAAACAATTTAAAAAGTAT
CATTGATAGCATTTCTAAAATTGCTTCAATAATTCCTGGTCTCTAG
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
